SMALL ANIMAL IMAGING RESEARCH PROGRAM

小动物影像研究计划

• 批准号: 8363912
• 负责人: RALPH P. MASON
• 金额: $ 0.8万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8363912
• 关键词: Anesthesia procedures; Animal Experimentation; Animals; Bioluminescence; Data; Development; Educational workshop; Equipment; Evaluation; Fluorescence; Funding; Grant; Human Resources; Image; Industry; Institution; International; Investigation; Magnetic Resonance Imaging; Metabolism; Modality; National Center for Research Resources; Positron-Emission Tomography; Principal Investigator; Protocols documentation; Radiolabeled; Radionuclide Imaging; Research; Research Infrastructure; Research Personnel; Resources; Small Animal Imaging Resource Programs; Source; United States National Institutes of Health; anticancer research; cancer imaging; cost; design; experience; implantation; in vivo; programs; radiotracer; symposium; tumor; tumor growth

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Small Animal Imaging Research Program at UT Southwestern provides critical infrastructure to facilitate small animal cancer imaging. Since inception, the SW-SAIRP has supported imaging in five modalities- MRI, PET, bioluminescence, fluorescence, and ¿-scintigraphy. As described below, these capabilities have been enhanced and expanded. SW-SAIRP investigators and support personnel advise on development of imaging protocols and optimal implementation of imaging investigations to enhance cancer research. Synthesis and radiolabeling are supported to generate materials not commercially available for imaging investigations. The experience of the investigators and availability of imaging infrastructure are designed to expand imaging opportunities for investigators at UT Southwestern and surrounding institutions, including academic centers and industry. New interactions are generated through an annual symposium, regular seminars, and participation in regional and international workshops and conferences. We have extensive experience in small animal research, tumor implantation, anesthesia and data evaluation. In addition, we can provide bioluminescence imaging to evaluate tumor growth. All five modalities are available and the MR components use the equipment within the Research Resource.

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 德克萨斯大学西南分校的小动物成像研究计划为促进小动物癌症成像提供了关键的基础设施。自成立以来，SW-SAIRP已经支持五种方式的成像-MRI、PET、生物发光、荧光和闪烁成像。如下所述，这些功能已得到增强和扩展。Sw-SAIRP研究人员和支持人员就成像方案的开发和成像研究的最佳实施提供建议，以加强癌症研究。支持合成和放射性标记，以产生不能用于成像研究的商业材料。研究人员的经验和成像基础设施的可用性旨在为德克萨斯大学西南分校和周边机构(包括学术中心和行业)的研究人员扩大成像机会。通过年度专题讨论会、定期研讨会以及参加区域和国际讲习班和会议，产生了新的互动。我们在小动物研究、肿瘤植入、麻醉和数据评估方面拥有丰富的经验。此外，我们可以提供生物发光成像来评估肿瘤的生长。所有五种模式都可用，MR组件使用研究资源中的设备。