Aniaml Shared Resources

动物共享资源

• 批准号: 8340282
• 负责人: BRUCE W. STILLMAN
• 金额: $ 48.47万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-17 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8340282
• 关键词: Animal Experimentation; Animal Model; Animals; Antibody Formation; Antigens; Basic Science; Cancer Center; Cancer Center at Cold Spring Harbor Laboratory; Cancer Model; Gene Targeting; Generations; Goals; Grant; Housing; Individual; Instruction; Laboratories; Modeling; Molecular Genetics; NCI Center for Cancer Research; Radiation; Research; Resource Sharing; Services; Therapeutic; Tissue Procurements; animal care; anticancer research; base; in vivo Model; innovation; member; model design; novel; response; tumor; tumorigenesis

PROJECT SUMMARY (See instructions): The Animal Shared Resource provides CSHL Cancer Center members with a service vital to their research. The goal of this Shared Resource is to support the use of animals in cancer research by providing housing, essential services, and technical support that cover all aspects of animal care and use. The need for research animals among individual laboratories that make up the Cancer Center ranges from the production of antibodies specific for tumor-related antigens, to tissue procurement, to the generation of novel cancer models designed to elucidate the genetic and molecular basis of tumorigenesis. In addition to providing these key services, the Animal Shared Resource provides space for two independent Shared Resources: the Gene Targeting and the Radiation Shared Resource.

项目总结（见说明）： 动物共享资源为CSHL癌症中心成员提供了对其研究至关重要的服务。 这个共享资源的目标是通过提供住房，基本服务和技术支持，涵盖动物护理和使用的各个方面，支持在癌症研究中使用动物。组成癌症中心的各个实验室对研究动物的需求范围从肿瘤相关抗原特异性抗体的生产到组织采购，再到旨在阐明肿瘤发生的遗传和分子基础的新型癌症模型的产生。除了提供这些关键服务外，动物共享资源还为两个独立的共享资源提供空间：基因靶向和辐射共享资源。