Developmental Funds
发展基金
基本信息
- 批准号:8340172
- 负责人:
- 金额:$ 45.83万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-05-23 至 2015-11-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
PROJECT SUMMARY (See instructions):
Developmental Funds
Building on superb recruitment. core facility development, pilot project productivity, and sparring but effective use of interim support, the Cancer Center requests $700,000 per year in developmental funds for faculty recruitment ($450,000), core facility enhancement ($75,000) and innovative pilot project funding ($175,000).
Going forward. the Center does not request funds specifically for interim (bridge) funding but would plan to use. as necessary and with justification, a small portion of the funds for that purpose, To assist with the Center's continued expansion, the budget requests a $50,000 (8%) increase over the current level. The Center's recruitment track record is outstanding. During the past six years, the Center has worked with 16 departments to support recruitment of 29 faculty with CCSG funds. All 29 faculty remain at UNC Chapel Hill and the UNC Lineberger. In 2009, this group of new faculty held ~$17.2 million yearly (total costs) in external funding. The Center also used Developmental Funds to develop five new core services, all of which have been incorporated into CCSG-supported shared resources. Developmental Funds also supported 45 pilot projects awards; 40 (89%) had produced a grant award or a publication by 2009. Pilot projects led to more than grant 20 major external funding awards. In addition, an emerging opportunity investment of Developmental Funds became a funded POI focused on DNA damage and repair in melanoma.
项目总结(见说明):
发展基金
建立在优秀的招聘基础上。核心设施的发展,试点项目的生产力,和争吵,但有效地利用临时支持,癌症中心要求每年700,000美元的发展资金用于教师招聘(450,000美元),核心设施的增强(75,000美元)和创新试点项目的资金(175,000美元)。
继续该中心不要求资金专门用于临时(桥梁)资金,但将计划使用。必要时,并有正当理由,一小部分资金用于这一目的,以协助中心的持续扩张,预算要求50,000美元(8%)增加比目前的水平。该中心的征聘记录非常出色。在过去的六年里,该中心已与16个部门合作,支持29名教师与CCSG基金的招聘。所有29名教师仍然在圣查佩尔山和圣莱恩伯格。在2009年,这组新的教师持有约1720万美元(总成本)的外部资金。该中心还利用发展基金开发了五项新的核心服务,所有这些服务都已纳入CCSG支持的共享资源。发展基金还支助了45个试点项目奖;到2009年,40个项目(89%)已获得赠款或出版物。试点项目促成了20多项重大外部资金赠款。此外,发展基金的一项新兴机会投资成为一项受资助的POI,重点关注黑色素瘤中的DNA损伤和修复。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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H. Shelton Earp其他文献
A Calcium-dependent Tyrosine Kinase Splice Variant in Human Monocytes
人单核细胞中钙依赖性酪氨酸激酶剪接变体
- DOI:
- 发表时间:
1998 - 期刊:
- 影响因子:4.8
- 作者:
Xiong Li;Deborah Hunter;John S. Morris;J. Stephen Haskill;H. Shelton Earp - 通讯作者:
H. Shelton Earp
Colorectal adenocarcinomas have increased EGFR ligand expression
- DOI:
10.1016/j.jamcollsurg.2006.05.219 - 发表时间:
2006-09-01 - 期刊:
- 影响因子:
- 作者:
Abigail S. Caudle;Laura Caskey;H. Shelton Earp;Benjamin Calvo - 通讯作者:
Benjamin Calvo
TAM family kinases as therapeutic targets at the interface of cancer and immunity
TAM 家族激酶作为癌症与免疫相互作用界面的治疗靶点
- DOI:
10.1038/s41571-023-00813-7 - 发表时间:
2023-09-04 - 期刊:
- 影响因子:82.200
- 作者:
Deborah DeRyckere;Justus M. Huelse;H. Shelton Earp;Douglas K. Graham - 通讯作者:
Douglas K. Graham
Exploiting structural variability in the kinase back-pocket to modulate polypharmacology of TAM inhibitors
利用激酶后袋的结构变异性来调节TAM抑制剂的多药理学特性
- DOI:
10.1016/j.ejmech.2025.117561 - 发表时间:
2025-06-05 - 期刊:
- 影响因子:5.900
- 作者:
Megan D. Hopkins;Dehui Zhang;Zhilong Chen;Andrew L. McIver;Justus M. Huelse;Jyoti P. Mahajan;Kaikai Lyu;Xiangbo Yang;Michael A. Stashko;Brittany Smith;Tsz Y. Yeung;H. Shelton Earp;Stephen V. Frye;Deborah DeRyckere;Dmitri Kireev;Douglas K. Graham;Xiaodong Wang - 通讯作者:
Xiaodong Wang
The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer
TAM 家族:在癌症中出错的磷脂酰丝氨酸感应受体酪氨酸激酶
- DOI:
10.1038/nrc3847 - 发表时间:
2014-11-24 - 期刊:
- 影响因子:66.800
- 作者:
Douglas K. Graham;Deborah DeRyckere;Kurtis D. Davies;H. Shelton Earp - 通讯作者:
H. Shelton Earp
H. Shelton Earp的其他文献
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{{ truncateString('H. Shelton Earp', 18)}}的其他基金
Divergent Roles of MerTK,Tyro3, and Axl in Pancreatic Cancer and Metastasis
MerTK、Tyro3 和 Axl 在胰腺癌和转移中的不同作用
- 批准号:
10601958 - 财政年份:2022
- 资助金额:
$ 45.83万 - 项目类别:
MerTK and the Innate Immune Response to Melanoma
MerTK 和对黑色素瘤的先天免疫反应
- 批准号:
9231607 - 财政年份:2017
- 资助金额:
$ 45.83万 - 项目类别:
Ack1: Activation and Consequences in Prostate Cancer
Ack1:前列腺癌中的激活和后果
- 批准号:
8270330 - 财政年份:2011
- 资助金额:
$ 45.83万 - 项目类别:
Ack1: Activation and Consequences in Prostate Cancer
Ack1:前列腺癌中的激活和后果
- 批准号:
8193120 - 财政年份:2011
- 资助金额:
$ 45.83万 - 项目类别:
NCCU-LCCC Partnership in Cancer Research (2 of 2)
NCCU-LCCC 癌症研究合作伙伴关系(2 of 2)
- 批准号:
8329650 - 财政年份:2010
- 资助金额:
$ 45.83万 - 项目类别:
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