Ready, Set, Snooz! A web-delivered, prescriptive intervention for pediatric sleep

准备好，开始，打瞌睡！

• 批准号: 8455977
• 负责人: Candice A Alfano
• 金额: $ 25.79万
• 依托单位: VIRTUALLY BETTER, INC.
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8455977
• 关键词: Acute; Address; Adult; Age; Alcohol or Other Drugs use; Anxiety; Architecture; Asthma; Award; Behavior; Behavior Therapy; Behavioral; Caregivers; Caring; Child; Childhood; Clinical; Collection; Computer software; Computers; Congresses; Data; Decision Making; Decision Trees; Development; Devices; Diabetes Mellitus; Disease; Early Intervention; Education; Educational Assessment; Educational process of instructing; Electronic Mail; Emotional; Ensure; Environment; Esthetics; Evidence based treatment; Extinction (Psychology); FDA approved; Family; Feedback; Food Hypersensitivity; Goals; Habits; Health Professional; Home environment; Hygiene; Hyperactive behavior; Infant; Internet; Intervention; Interview; Investigation; Knowledge; Lead; Learning; Light; Link; Measures; Mental Depression; Methodology; Methods; Motivation; Obesity; Online Systems; Outcome; Overweight; Parent-Child Relations; Parents; Pattern; Pharmaceutical Preparations; Phase; Play; Population; Problem Solving; Problem behavior; Public Health; Questionnaires; Randomized; Relaxation Therapy; Reporting; Research; Research Personnel; Resources; Rewards; Role; Schedule; School-Age Population; Self Efficacy; Self Management; Services; Sleep; Sleep Disorders; Small Business Innovation Research Grant; Social Environment; Stimulus; Structure; System; Tablets; Techniques; Technology; Telephone; Testing; Text; Time; Toddler; Token Economy; Training; Treatment outcome; United States Dept. of Health and Human Services; Video Games; active control; age group; base; behavior influence; behavioral health; clinical efficacy; commercialization; conduct problem; cost; data management; design; efficacy evaluation; evidence base; experience; improved; inattention; innovation; intervention program; novel; novel strategies; programs; prospective; psychoeducation; public health relevance; rehearsal; service intervention; skills; social; statistics; treatment program; treatment trial; trial comparing; usability; user-friendly; virtual; virtual reality

DESCRIPTION (provided by applicant): Insufficient sleep in children is recognized by Congress and the Department of Health and Human Services as a high priority target for clinical scientific investigation given its consist link with enduring physical, emotional and behavioral problems, including overweight/obesity, inattention, hyperactivity, learning problems, conduct problems, substance use, anxiety, and depression. Behaviorally-based interventions have been proven efficacious for pediatric sleep difficulties and disorders, but they remain under utilized, with approximately 80% [37] of children being prescribed sleep medication despite no FDA approved medications for this population. Given that up to 70% of children in the U.S. age 10 and under experience a sleep problem several times per week [1], and researchers have shown behavioral sleep interventions to be efficacious, we must address this under-utilization by developing more accessible, affordable, and engaging interventions for children and their caregivers. Software-based interventions offer an improved means of disseminating empirically-supported treatments for sleep directly to families, just as they have other pediatric conditions such as diabetes, asthma, and social anxiety. However, in light of the myriad of web-based interventions currently available, software alone does not address issues associated with under-utilization. Development and incorporation of more interactive, experiential, and game-based components such as virtual reality (VR) and token economies, will lead to greater engagement and motivation for use, ultimately resulting in better treatment outcomes. This technological paradigm shift to more experientially, context-based, and interactive content offers distinct advantages over traditional interventions in its ability to provide virtual skills-based practice with real-time feedback, opportunities for entertaining gaming, and more engaging formats of psychoeducation. Utilization of VR technology as part of an internet-delivered behavioral treatment program for children is a novel approach to ensuring access to evidence-based care and optimizing outcomes. This intervention will be the first program for children with sleep problems to leverage a web-based platform that is engaging, educational, skills-based, and easily accessible. This Phase I SBIR will build an intervention called Ready, Set, Snooz", a user-friendly, interactive, and affordable web-based treatment program with a high potential for broad dissemination, adaptation and commercialization across different disease conditions beyond Phase II. This web-based intervention will consist of three Clinical Components: 1) Sleep Tracking, 2) Education/Skill Development, and 3) Virtual Sleep Training. All information will be presented in a sequenced format as to build upon skills already learned/practiced. Additionally, an imbedded virtual game will be available to all users who can exchange virtual tokens earned during the intervention for virtual game content and access to new game levels, a methodology common among many smart device games today. We will evaluate the feasibility, credibility, and acceptability of the treatment program, as well as initial clinical efficacy basedon knowledge, motivation/self- efficacy, and changes in actual sleep patterns and behaviors. Our intervention, Ready, Set, Snooz", will represent the first prescriptive, engaging, and interactive web-based intervention for school-aged children with sleep difficulties, requiring active participation by both the child and parent. We believe this intervention will surpass existing approaches for child-focused software programs based on its novelty, aesthetics, ease of use, and acceptance/promotion by health care professionals and families. If successful, we envision that the VR program will serve as a template for interactive VR interventions for children with other conditions requiring self-management, such as asthma, diabetes, and food allergies. The promise of commercial opportunity is significant in an era in which there is increasingly widespread access to and everyday use of computers, smart phones, and tablet technologies.

描述（由申请人提供）：儿童睡眠不足被国会和卫生与公众服务部确认为临床科学研究的高度优先目标，因为其与持久的身体，情绪和行为问题有关，包括超重/肥胖，注意力不集中，多动，学习问题，行为问题，物质使用，焦虑和抑郁。基于行为的干预措施已被证明对儿童睡眠困难和障碍有效，但它们仍然没有得到充分利用，尽管没有FDA批准的药物用于这一人群，但大约80%的儿童被处方睡眠药物。鉴于美国10岁及以下儿童中高达70%的人每周都会经历几次睡眠问题，研究人员已经证明行为睡眠干预是有效的，我们必须通过为儿童及其照顾者开发更容易获得，负担得起和参与的干预措施来解决这种利用不足的问题。 基于软件的干预措施提供了一种改进的方法，可以直接向家庭传播医学支持的睡眠治疗，就像他们患有糖尿病，哮喘和社交焦虑等其他儿科疾病一样。然而，鉴于目前可利用的网络干预措施繁多，软件本身并不能解决与利用不足有关的问题。开发和整合更具互动性，体验性和基于游戏的组件，如虚拟现实（VR）和代币经济，将导致更大的参与和使用动机，最终导致更好的治疗结果。这种技术范式向更注重体验、基于情境和互动的内容的转变，与传统干预相比具有明显的优势，因为它能够提供基于技能的虚拟实践，并提供实时反馈、娱乐游戏的机会以及更具吸引力的心理教育形式。利用VR技术作为互联网提供的儿童行为治疗计划的一部分，是确保获得循证护理和优化结果的一种新方法。这项干预将是第一个针对睡眠问题儿童的计划，利用一个基于网络的平台，该平台具有吸引力，教育性，技能性，易于访问。 这一第一阶段SBIR将建立一个名为“准备，设置，Snooz”的干预措施，这是一个用户友好，互动和负担得起的基于网络的治疗计划，具有广泛传播，适应和商业化的潜力，超过了第二阶段的不同疾病条件。这种基于网络的干预将包括三个临床部分：1）睡眠跟踪，2）教育/技能发展，3）虚拟睡眠训练。所有信息将以有序的格式呈现，以建立在已经学习/实践的技能基础上。此外，嵌入式虚拟游戏将提供给所有用户，他们可以交换在虚拟游戏内容干预期间获得的虚拟令牌并访问新的游戏级别，这是当今许多智能设备游戏中常见的方法。我们将评估治疗方案的可行性、可信度和可接受性，以及基于知识、动机/自我效能以及实际睡眠模式和行为变化的初步临床疗效。 我们的干预，准备，设置，Snooz”，将代表第一个规定的，从事和互动的网络为基础的干预学龄儿童的睡眠困难，需要积极参与的儿童和家长。我们相信，这种干预将超越现有的方法，以儿童为中心的软件程序的基础上，其新奇，美观，易用性，并接受/推广的医疗保健专业人员和家庭。如果成功的话，我们设想VR项目将作为交互式VR干预的模板，用于患有其他需要自我管理的疾病的儿童，如哮喘，糖尿病和食物过敏。在计算机、智能手机和平板电脑技术日益普及和日常使用的时代，商业机会的前景非常重要。