Engagement in Longevity and Medicine (ELM)

参与长寿与医学 (ELM)

• 批准号: 9793747
• 负责人: JOSHUA CHODOSH
• 金额: $ 95.14万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-15 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9793747
• 关键词: Address; Adult; Age; Aging; Alzheimer' s disease related dementia; Asians; Behavioral Research; Biomedical Research; Businesses; Censuses; Chronic; Chronic Disease; Clinic; Clinical; Clinical Research; Clinical Trials; Cognitive; Communication; Communities; Community Health; Community Health Aides; Community Networks; Competence; Complex; Computerized Medical Record; Consent; Country; Development; Diagnosis; Early Diagnosis; Education; Elderly; Electronic Health Record; Face; Family; Federally Qualified Health Center; Future; Goals; Growth; Health; Health Communication; Health Personnel; Healthcare; Hospitals; Human Subject Research; Immigrant; Impaired cognition; Impairment; Individual; Infrastructure; Intervention; Knowledge; Latino; Limited English Proficiency; Logistics; Longevity; Low income; Medicine; Methods; Minority; Modeling; Municipalities; National Institute on Aging; New York; New York City; Older Population; Outcomes Research; Participant; Patient Recruitments; Patient-Focused Outcomes; Patients; Plant Roots; Population; Population Heterogeneity; Population Research; Population trends; Prevention; Provider; Recording of previous events; Registries; Research; Research Infrastructure; Research Personnel; Science; Sensory; Social Work; System; Technology; Testing; Training; Training Programs; Treatment Protocols; United States; Universities; Ursidae Family; Veterans; Work; age group; aging population; base; community partnership; community setting; disparity reduction; ethnic minority population; experience; health disparity; health literacy; innovation; interest; member; multiple chronic conditions; novel; racial minority; recruit; repository; retention rate; service providers; simulation

PROJECT SUMMARY/ABSTRACT The goal of this project is to establish a centralized research infrastructure that harnesses New York University (NYU) Langone Health’s clinical and community partnerships throughout New York City to strengthen and advance the science of community engagement, recruitment and retention in aging and Alzheimer’s and related dementia (ADRD) research. Despite the tremendous growth in the older adult and elderly population, particularly among racial and ethnic minorities, these individuals are underrepresented in clinical research. Older age participants face challenges that differ from younger age populations in engagement, recruitment and retention in human subjects research. These include concerns about chronic disease complexities, mobility limitations, and cognitive and sensory impairments that may limit access to research opportunities or capacity to consent. As a result, the evidence of what works in healthcare interventions is less generalizable to older populations, particularly for minority and low-income communities despite the recognition of the disproportionate burden of health disparities among these communities. To address these concerns, the NYU Engagement in Longevity and Medicine (ELM) Research Collaborative will evaluate and disseminate best practices in engaging, recruiting and retaining older populations, stimulate the development and testing of innovative community-engaged and technology-based approaches to participant recruitment in clinical and community settings, and strengthen communication and messaging strategies tailored to diverse aging research populations that are inclusive of ADRD communities and representative of the National Institute on Aging’s priority populations. To increase engagement, recruitment, and retention of older age subjects into aging and ADRD research, the NYU ELM Research Collaborative will: 1) establish a centralized infrastructure including community members, clinical researchers, and patient and family stakeholders in aging and ADRD research; 2) analyze and evaluate what is currently known about successful strategies and challenges in recruitment and retention; 3) develop innovative approaches for education and engagement using electronic health record systems and community navigators rooted in the community health worker model; 4) build and deploy a novel training program for research teams using simulation with actors as potential subjects; and 5) develop a broad-based research registry of interested potential subjects reflective of the diversity of the older adult US population. This study will provide immediate benefit to ongoing aging and ADRD clinical trials and substantial support to future trials.

项目概要/摘要 该项目的目标是建立一个利用纽约大学的集中研究基础设施 (纽约大学) Langone Health 在整个纽约市的临床和社区合作伙伴关系，以加强和 推进老龄化、阿尔茨海默病及相关领域的社区参与、招募和保留科学 痴呆症（ADRD）研究。尽管老年人口和老年人口大幅增长，特别是 在少数种族和族裔中，这些人在临床研究中的代表性不足。年龄较大 参与者在参与、招募和保留方面面临着与年轻群体不同的挑战 在人类受试者研究中。这些包括对慢性疾病复杂性、行动限制的担忧， 认知和感觉障碍可能会限制获得研究机会或同意能力。 因此，医疗保健干预措施有效的证据不太适用于老年人群， 特别是对于少数族裔和低收入社区而言，尽管人们认识到 这些社区之间的健康差异。 为了解决这些问题，纽约大学长寿与医学 (ELM) 研究合作组织将 评估和传播吸引、招募和留住老年人口的最佳做法，刺激 开发和测试创新的社区参与和基于技术的参与者方法 在临床和社区环境中招募人员，并加强定制的沟通和信息传递策略 包括 ADRD 社区和国家代表在内的不同老龄化研究人群 老龄化研究所的优先人群。 为了增加老年受试者对老龄化和 ADRD 研究的参与、招募和保留， 纽约大学 ELM 研究合作组织将：1）建立一个包括社区成员在内的集中式基础设施， 老龄化和 ADRD 研究中的临床研究人员、患者和家庭利益相关者； 2）分析评价 目前对招聘和保留方面的成功战略和挑战有何了解； 3）开发 利用电子健康记录系统和社区进行教育和参与的创新方法 植根于社区卫生工作者模式的导航者； 4）制定并部署新颖的培训计划 研究团队使用以演员为潜在受试者的模拟； 5）开展基础广泛的研究 反映美国老年人口多样性的感兴趣的潜在主题的登记册。这项研究将 为正在进行的衰老和 ADRD 临床试验提供直接益处，并为未来的试验提供实质性支持。