USC Norris Comprehensive Cancer Center (CORE) Support

南加州大学诺里斯综合癌症中心 (CORE) 支持

• 批准号: 8788971
• 负责人: STEPHEN B GRUBER
• 金额: $ 0.42万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-01 至 2015-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8788971
• 关键词: Area; California; Cancer Center; Cancer Center Support Grant; Cancer Control Research; Cancer Hospital; Country; Development; Developmental Therapeutics Program; Diagnosis; Direct Costs; Epigenetic Process; Evaluation; Fostering; Funding; Grant; Head; Leadership; Malignant Neoplasms; Malignant neoplasm of gastrointestinal tract; Molecular Genetics; Peer Review; Pilot Projects; Prevention; Prevention education; Recruitment Activity; Regulation; Research; Research Infrastructure; Research Peer Review; Research Personnel; Resource Sharing; Resources; Translating; Translational Research; USC/Norris Comprehensive Cancer Center and Hospital; Universities; Urogenital Cancer; Wages; Woman; anticancer research; cancer epidemiology; cancer therapy; innovation; leukemia/lymphoma; member; population based; programs; research and development; tumor microenvironment

DESCRIPTION (provided by applicant): The USC Norris Comprehensive Cancer Center at the University of Southern California was founded in 1971 and has been continuously supported by a Cancer Center Support Grant since 1973. It has developed into a major regional and national resource for cancer research, treatment, prevention and education. Center facilities have been built and developed with support from the NCI, the University and the Kenneth Norris Jr. Cancer Hospital, which is an integral part of the Cancer Center. The Center underwent a major expansion with the addition of the Norman Topping Tower in 1996 and the Harlyne Norris Research Tower in 2007. The Center's 198 members are organized into five thematic and five translational research programs, including a "bridge" program in developmental therapeutics. The thematic programs are headed by senior investigators in the fields of molecular genetics, epigenetics and regulation, tumor microenvironment, cancer epidemiology and cancer control research. The translational programs, which provide focus to our transdisciplinary research efforts, are in developmental therapeutics, genitourinary cancers, gastrointestinal cancers, women's cancers and leukemia and lymphoma. This application is for: 1) partial salary support for the Center's senior leadership, who are responsible for planning and overseeing our research efforts; 2) support for program planning and evaluation to keep the Center at the forefront of cancer research; 3) support for the administrative infrastructure of the Center; 4) partial support for the Center's 11 shared resources which facilitate the conduct of our peer-reviewed research; and 5) support for developmental funds to help us recruit new investigators in areas we have targeted for expansion and to fund innovative pilot projects. Continued funding from the Cancer Center Core Support Grant will allow us to build on our strengths in basic and population-based research and to translate our underlying expertise into strong, peer-reviewed funded research programs focused on cancers of major consequence in this country. Cancer Center members currently hold grants totaling $125 million in direct costs, with $43 million of that coming from NCI (all exclusive of the CCSG).

描述(由申请人提供)：南加州大学南加州大学诺里斯综合癌症中心成立于1971年，自1973年以来一直得到癌症中心支持拨款的支持。它已发展成为癌症研究、治疗、预防和教育的主要区域和国家资源。中心设施已经在NCI、大学和小Kenneth Norris Jr.的支持下建造和发展。癌症医院，这是癌症中心不可或缺的一部分。该中心经历了一次重大的扩建，1996年增加了诺曼顶楼，2007年增加了哈林·诺里斯研究塔。该中心的198名成员被组织成五个主题研究项目和五个翻译研究项目，其中包括一个发展治疗学的“桥梁”项目。这些主题项目由分子遗传学、表观遗传学和调控、肿瘤微环境、癌症流行病学和癌症控制研究领域的高级研究人员领导。为我们的跨学科研究工作提供重点的翻译计划涉及发育疗法、泌尿生殖系癌症、胃肠道癌症、女性癌症以及白血病和淋巴瘤。这项申请用于：1)为负责规划和监督我们的研究工作的中心高级领导层提供部分工资支持；2)支持项目规划和评估，以保持中心在癌症研究方面的领先地位；3)支持中心的行政基础设施；4)部分支持中心的11个共享资源，以促进我们进行同行评议的研究；以及5)支持发展基金，以帮助我们在我们选定的扩张目标领域招募新的研究人员，并为创新的试点项目提供资金。癌症中心核心支持赠款的持续资助将使我们能够巩固我们在基础研究和基于人群的研究方面的优势，并将我们的潜在专业知识转化为强大的、同行评议资助的研究项目，重点关注这个国家的主要后果癌症。癌症中心成员目前持有总计1.25亿美元的直接成本赠款，其中4300万美元来自NCI(不包括CCSG)。