PATIENTS: PATient-centered Involvement in Evaluating effectivNess of Treatment

患者：以患者为中心参与评估治疗效果

• 批准号: 9357515
• 负责人: C. DANIEL MULLINS
• 金额: $ 96.41万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2019-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9357515
• 关键词: PATIENTS; PATient; centered; Involvement; Evaluating

DESCRIPTION (provided by the applicant): Incorporating patients' perspectives can improve healthcare research and delivery. When patients are included in healthcare research, they are empowered to ask and receive relevant answers to questions they have about their health. Patient-centered outcomes research (PCOR) is designed to provide meaningful evidence that enables informed healthcare decision making by patients and other stakeholders. The University of Maryland (UM) is applying the concept of continuous patient engagement to a long history of successful community based participatory research to propose an innovative approach to PATient-centered Involvement in Evaluating the effectiveNess of Treatments (PATIENTS). PATIENTS is designed to enhance existing UM infrastructure to: (1) Foster sustainable partnerships with local, regional, and national communities of diverse patients and healthcare systems to improve PCOR, investigators' cultural competency and, ultimately, health outcomes; (2) Conduct and expand PCOR in partnership with patients and healthcare delivery systems that will better inform patient-centered health care decision making and healthcare systems design; and (3) Advance dissemination and implementation strategies for PCOR findings for patients, health care providers, and healthcare systems to utilize evidence-based interventions. A major focus of PATIENTS will be to select health outcomes and comparator interventions that matter to diverse patients or their surrogates, address the applicability and feasibility of PCOR across healthcare systems, and accelerate adoption of effective interventions through implementation science. The cornerstone of the PATIENTS program is UM, including the Baltimore (UMB) and College Park (UMCP) campuses, the University of Maryland Medical Center (UMMC) and related clinics and hospitals within the UM network; however, it is the inclusion of diverse patient communities and healthcare systems into the infrastructure that will ensure meaningful stakeholder involvement. Four individual investigator research projects support the development of the PCOR infrastructure and add to the sustainability of partnerships.

描述（由申请人提供）：阐明患者的观点可以改善医疗保健研究和提供。当患者被纳入医疗保健研究时，他们有权询问并获得有关其健康问题的相关答案。以患者为中心的结果研究（PCOR）旨在提供有意义的证据，使患者和其他利益相关者能够做出明智的医疗决策。马里兰州大学（UM）正在将持续患者参与的概念应用于具有悠久历史的成功的基于社区的参与性研究，以提出一种创新的方法， 参与评估治疗的有效性（患者）。病人的目的是加强现有的UM基础设施：（1）促进可持续的伙伴关系，与当地，区域， （2）与患者和医疗保健提供系统合作开展和扩大变革和组织振兴方案，更好地为以患者为中心的医疗保健决策和医疗保健系统设计提供信息;和（3）推进PCOR结果的传播和实施战略，以便患者、医疗保健提供者和医疗保健系统利用循证干预措施。患者的一个主要重点是选择对不同患者或其代理人重要的健康结局和比较干预措施，解决PCOR在整个医疗保健系统中的适用性和可行性，并通过实施科学加速采用有效的干预措施。 患者计划的基石是UM，包括巴尔的摩（UMB）和学院公园（UMCP）校区、马里兰州大学医学中心（UMMC）以及UM网络内的相关诊所和医院;然而，将不同的患者社区和医疗保健系统纳入基础设施将确保有意义的利益相关者参与。四个独立调查员研究项目支持变革和组织振兴方案基础设施的发展，并增强了伙伴关系的可持续性。

项目成果

Patients' early engagement in research proposal development (PEER-PD): patients guiding the proposal writing.

患者早期参与研究提案制定（PEER-PD）：患者指导提案撰写。

• DOI: 10.2217/cer-2018-0129
• 发表时间: 2019
• 期刊: Journal of comparative effectiveness research
• 影响因子: 2.1
• 作者: Natafgi,Nabil;Tafari,ATsahai;Chauhan,Cynthia;Bekelman,JustinE;Mullins,CDaniel
• 通讯作者: Mullins,CDaniel

Insights Into the Experience of Liver Transplant Recipients With Alcoholic Liver Disease: A Descriptive Qualitative Study.

深入了解肝移植受者患有酒精性肝病的经历：一项描述性定性研究。

• DOI: 10.1097/txd.0000000000000951
• 发表时间: 2019
• 期刊: Transplantation direct
• 影响因子: 2.3
• 作者: Hochheimer,Martin;Moreland,MelissaL;Tuten,Michelle;LaMattina,John;Connelly,Mark;Sacco,Paul
• 通讯作者: Sacco,Paul

A framework for pharmacist-assisted medication adherence in hard-to-reach patients.

药剂师协助难以接触到的患者坚持用药的框架。

• DOI: 10.1016/j.sapharm.2014.11.010
• 发表时间: 2015
• 期刊: Research in social & administrative pharmacy : RSAP
• 作者: Wiener,EmilyS;Mullins,CDaniel;Pincus,KathleenJ
• 通讯作者: Pincus,KathleenJ

Querying stakeholders to inform comparative effectiveness research.

询问利益相关者，为比较有效性研究提供信息。

• DOI: 10.2217/cer-2016-0082
• 发表时间: 2017
• 期刊: Journal of comparative effectiveness research
• 影响因子: 2.1
• 作者: Hong,YoonDuk;Goto,Daisuke;Mullins,CDaniel
• 通讯作者: Mullins,CDaniel

Relieving acute pain (RAP) study: a proof-of-concept protocol for a randomised, double-blind, placebo-controlled trial.

缓解急性疼痛 (RAP) 研究：一项随机、双盲、安慰剂对照试验的概念验证方案。

• DOI: 10.1136/bmjopen-2019-030623
• 发表时间: 2019
• 期刊: BMJ open
• 影响因子: 2.9
• 作者: Colloca,Luana;Lee,SeEun;Luhowy,MeghanNichole;Haycock,Nathaniel;Okusogu,Chika;Yim,Soojin;Raghuraman,Nandini;Goodfellow,Robert;Murray,RobertScott;Casper,Patricia;Lee,Myounghee;Scalea,Thomas;Fouche,Yvette;Murthi,Sarah
• 通讯作者: Murthi,Sarah