Bioinformatics "Train the Trainer" (T3): The Integration of Bioinformatics into an Undergraduate Biology Curriculum

项目摘要-摘要 高通量技术在生物医学、行为学和临床研究中的应用已成为 广泛，需要专业技能来有效地设计实验，分析大型数据集， 将新数据与现有的大型数据集集成，以解决这些领域的复杂问题。学生在STEM 专业学生需要获得这些技能，以便在生物医学，行为和临床研究中发挥作用 职场我们拟议的生物信息学“培训培训者”（T3）项目将促进和支持以下方面的培训： 生物信息学技能的学院和大学本科科学导师，使他们能够有效地 将生物信息学纳入科学课程，帮助学生为21世纪做好准备 职场该项目有三个创新组成部分。第一部分是为期7天的短期课程， 本科生导师与实践活动，灌输能力和信心，生物信息学。 该课程将有两个湿台实验室和生物信息学的经验，其中的组合，我们 我相信，这是充分理解基因组结构背后的生物学以及基因组之间关系的关键。 这些结构和进化、遗传、疾病和人类健康。第二个是一个专门的网站， 链接到资源，生物信息学工具，项目档案，案例研究，以及建立一个社区的论坛， 生物信息学培训师，以便课程参与者可以分享课程后的经验，交流想法，并提供 点对点指导该项目的第三个组成部分是一个严格的评估计划， 领导者对课程的反馈，确定生物信息学整合的挑战和成功， 本科课程，并确定项目的有效性方面的干保留和干 大学生的职业抱负。

Project Summary-Abstract The application of high-throughput technologies in biomedical, behavioral, and clinical research has become widespread and requires specialized skills to effectively design experiments, analyze large datasets and integrate new data with existing large datasets to solve complex problems in these fields. Students in STEM majors will need to acquire these skills in order to be effective in the biomedical, behavioral, and clinical research workplace. Our proposed Bioinformatics “Train the Trainer” (T3) Project will promote and support training in bioinformatics skills for college and university undergraduate science instructors so that they can effectively integrate bioinformatics into their science curricula and help their students be prepared for the 21st century workplace. The project has three innovative components. The first component is a 7-day short course for undergraduate instructors with hands-on activities for instilling competence and confidence in bioinformatics. The course will have both wet-bench laboratory and bioinformatics experiences, the combination of which, we believe, is key to fully understanding the biology underlying genome structures and the relationship between those structures and evolution, inheritance, disease, and human health. The second is a dedicated website with links to resources, bioinformatics tools, project archives, case studies, and a forum for building a Community of Bioinformatics Trainers so course participants can share post-course experiences, exchange ideas, and provide peer-to-peer mentoring. The third component of the project is a rigorous evaluation plan that will provide project leaders with feedback on the course, identify challenges and successes with bioinformatics integration into undergraduate curriculum, and determine the effectiveness of the project in terms of STEM retention and STEM career aspirations for undergraduates.