Northwestern University Molecular and Translational Cardiovascular Training Program

西北大学分子与转化心血管培训项目

• 批准号: 9358906
• 负责人: Hossein Ardehali
• 金额: $ 16.82万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9358906
• 关键词: Cardiovascular system; Molecular; Training Programs; Universities

This proposal is a new application for basic cardiovascular Research Training at Northwestern University Feinberg School of Medicine. We have witnessed rapid advances in the scientific knowledge in cardiovascular (CV) disease in the past few years, and this has created unparalleled opportunities for new discoveries that can potentially lead to better treatment options. The objective of the Northwestern University Molecular and Translational Cardiovascular Training Program (NMTCTP) is to request funding for a unique and comprehensive program that is designed to train the next generation of researchers interested in CV physiology and disease. This first time proposal request comes at a time of substantial and sustained growth in cardiovascular research and the research enterprise of the Feinberg School of Medicine. NMTCTP is unique in that it will encompass three distinct areas of CV concentration: genomics/proteomics, biology of vessels, and metabolism. The program will include 23 outstanding research scientists as mentors, who have extensive experience in pre- and postdoctoral training and have collaborated with other mentors or scientists nationally and internationally, and a statistical mentor. Our program will also use the expertise of a group of investigators who will serve as translational advisors to assist our mentees with the clinical implications of their basic science findings, and to provide career advice to them. This will provide a training environment that enables trainees to obtain the full range of exposure and training they need to become the next generation of researchers and leaders in CV disease. There is no current program that emphasizes the basic mechanisms of CV disease at Northwestern University. Predoctoral trainees will come from the Driskill Graduate Program in Life Sciences (DGP) and the Medical Scientist Program (MSTP), while postdoctoral trainees will be PhD and MD research fellows. The program will be regularly and rigorously evaluated using different mechanisms, including evaluation by an Executive Committee, an External Advisory Committee, the trainees, and by tracking the progress of former trainees. We have started a CV didactic course and a Northwestern CV Research Day, which will highlight the accomplishments of our trainees and will allow close interaction between our mentees and the invited speaker. NMTCTP also has mechanisms in place to catalyze interactions between our trainees with scientists at other institutions (by supporting our trainees to attend national conferences) and by allowing them to invite and host outside speakers. The program requests support for 2 postdoctoral fellows and 1 predoctoral student per year in the first year, and 4 postdoctoral and 2 predoctoral trainees in years 2-5 of the grant. Each trainee will be supported for a total of 2 years. Funding of NMTCTP will provide Northwestern with the means to stimulate cross-disciplinary collaboration, and train the next generation of scientists that will work at the forefront of CV research, and understand the translational implication of their findings.

该建议是西北大学基本心血管研究培训的新申请 费恩伯格医学院。我们目睹了科学知识的快速发展 在过去的几年中，心血管疾病（简历）疾病，这为新的机会创造了无与伦比的机会 有可能导致更好治疗选择的发现。西北大学的目标 分子和转化的心血管训练计划（NMTCTP）是要为独特的 旨在培训对CV感兴趣的下一代研究人员的综合计划 生理和疾病。第一次提案请求是在实质性和持续增长的时候出现的 在Feinberg医学院的心血管研究和研究企业中。 NMTCTP是 独特的是，它将包括简历浓度的三个不同领域：基因组学/蛋白质组学，生物学 血管和代谢。该计划将包括23位杰出的研究科学家作为导师 在学前和博士后培训方面的丰富经验，并与其他导师或科学家合作 在国内和国际上，以及统计导师。我们的计划还将使用一组的专业知识 将担任转化顾问的调查人员，以协助我们的受训者实现临床意义 他们的基础科学发现，并向他们提供职业建议。这将提供培训环境 这使学员能够获得他们成为下一个的全部曝光和培训 CV疾病的研究人员和领导者的产生。没有当前的程序强调基本 西北大学简历疾病的机制。托里斯特学员将来自driskill 生命科学研究生课程（DGP）和医学科学家计划（MSTP），而博士后 学员将是博士和医学博士研究研究员。该程序将定期和严格评估 不同的机制，包括执行委员会，外部咨询委员会的评估， 受训者，并通过跟踪前学员的进步。我们已经开始了简历教学课程和 西北简历研究日，将重点介绍我们学员的成就，并将允许关闭 我们的受训者与受邀演讲者之间的互动。 NMTCTP也具有适当的机制 催化学员与其他机构科学家之间的互动（通过支持我们的受训者 参加民族会议），并允许他们邀请和主持外部演讲者。程序请求 支持2个博士后研究员和第一年的1名前学生，以及4个博士后和 2授予赠款2 - 5年的2年学员。每个学员将得到总计2年的支持。资金 NMTCTP将为西北地区提供刺激跨学科合作和训练的手段 下一代的科学家将在简历研究的最前沿工作，并了解 他们发现的翻译意义。