Muscle thermogenesis in models of predisposition to obesity

肥胖倾向模型中的肌肉生热作用

• 批准号: nhmrc : 1005935
• 负责人: A/Pr Zane Andrews
• 金额: $ 31.29万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/muscle-thermogenesis-models-predisposition-obesity/109125
• 关键词: Muscle; thermogenesis; models; predisposition; obesity

Obesity is a major health crisis, but effective treatments remain elusive. Body weight is determined by a balance of food intake and energy expenditure. Understanding both sides of this equation is essential to combating obesity. This project will show that the rate at which muscle uses energy is an important determinant of energy balance and contributes to the propensity to become obese. The work will define muscle as a target for developing anti-obesity therapies.

肥胖是一个主要的健康危机，但有效的治疗方法仍然难以捉摸。体重是由食物摄入和能量消耗的平衡决定的。了解这个等式的两边对于对抗肥胖至关重要。该项目将表明，肌肉使用能量的速率是能量平衡的重要决定因素，并有助于肥胖的倾向。这项工作将肌肉定义为开发抗肥胖疗法的目标。