Neural sensing of hunger links homeostatic and reward pathways

饥饿的神经感知将稳态和奖励途径联系起来

• 批准号: nhmrc : GNT1126724
• 负责人: A/Pr Zane Andrews
• 金额: $ 44.44万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/neural-sensing-hunger-reward-pathways/1347569
• 关键词: Neural; sensing; hunger; links; homeostatic

Cells in the brain that respond to signals of hunger also increase motivation to obtain food and there reward value of food. This proposal examines how these hunger cells, called AgRP cells, sense changes in metabolic state in order to increase motivation and food reward pathways. We believe that understanding this process may help us understand why obese individuals overeat foods high in sugar and fat.

大脑中对饥饿信号做出反应的细胞也会增加获取食物的动力，并奖励食物的价值。该提案研究了这些饥饿细胞（称为 AgRP 细胞）如何感知代谢状态的变化，以增加动力和食物奖励途径。我们相信，了解这个过程可能有助于我们理解为什么肥胖者会过量食用高糖和高脂肪的食物。