Rio Grande Valley Alzheimer's Resource Center for Minority Aging Research: Partnerships for Progress

里奥格兰德河谷阿尔茨海默病少数族裔老龄化研究资源中心：合作促进进步

• 批准号: 9532548
• 负责人: Gladys E. Maestre
• 金额: $ 65.76万
• 依托单位: UNIVERSITY OF TEXAS RIO GRANDE VALLEY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9532548
• 关键词: Achievement; Address; Affect; Aging; Alzheimer' s Disease; Alzheimer' s disease risk; Behavior; Behavioral; Behavioral Research; Biomedical Research; Cardiovascular Diseases; Cardiovascular system; Cognitive; Communities; Community Health Centers; Complex; Data Collection; Development; Diabetes Mellitus; Diagnosis; Discipline; Discrimination; Disease; Economic Burden; Educational Background; Elderly; Ethnic group; Exhibits; Exposure to; Faculty; Family; Fostering; Funding; Genetic; Goals; Growth; Health; Health Personnel; Health Promotion; Healthcare; Healthcare Systems; High Prevalence; Hispanic-serving Institution; Hispanics; Individual; Institutes; Institution; Intervention; Kansas; Knowledge; Latino; Lead; Leadership; Life Style; Measurement; Mentors; Mentorship; Mexico; Minority; Minority-Serving Institution; Modeling; Neuropsychology; Neurosciences; Obesity; Pathway interactions; Personal Satisfaction; Pilot Projects; Population; Positioning Attribute; Poverty; Prevention; Public Health; Research; Research Infrastructure; Research Personnel; Research Training; Resources; Risk; Risk Factors; Social Change; Source; South Texas; Statistical Data Interpretation; Testing; Texas; Textiles; Time; Training; Training Programs; Training and Education; Underrepresented Groups; Universities; Vision; Washington; career; career development; cohort; community organizations; early life adversity; education research; educational atmosphere; evidence base; experience; health disparity; health economics; improved; innovation; minority health; multidisciplinary; neuroimaging; programs; racial and ethnic; recruit; social; socioeconomics; trait; working group

Summary OVERALL Alzheimer´s disease (AD) is an aging-associated disorder that disproportionately impacts Hispanics/Latinos, who exhibit AD rates 1.5 times higher and average onset 7 years earlier than do older whites. Predicted growth of the US Hispanic population, particularly faster in Texas, portends further exacerbation of the disproportion- ate health and economic burdens of elevated AD in Hispanics. There is a shortage of researchers focused on AD and related disorders (ADRD) in Hispanics, particularly from underrepresented racial/ethnic groups. To overcome these barriers, the proposed AD Resource Center for Minority Aging Research (AD-RCMAR) at the University of Texas Rio Grande Valley (UTRGV), one of the nation's largest Hispanic-serving institutions, will combine evidence-based mentoring and support mechanisms to develop and promote a first-rate regional and national cadre of researchers, particularly from under-represented groups, to analyze the complex mecha- nisms and interacting factors that contribute to Hispanics' disparate vulnerabilities to AD. The Center will sup- port identification of pathways and developmental time points at which changes in social circumstances and behavior can exert the largest favorable impacts on prevention and progression of AD among Hispanics. The UTRGV AD-RCMAR will exploit its unique resources to develop infrastructure and data collections that will at- tract and support researchers from multiple disciplines and at different scientific career stages, and allow them to conduct research aimed at reducing the impacts of AD on Hispanics. The socio-demographic profile of UTRGV reflects that of its local community, positioning the Center uniquely to advance studies of disparities in health and health care and contribute innovative solutions to improve minorities' health. We will achieve the Center's goals via 4 specific aims: 1) to identify, engage, mentor, and provide high-quality training and individu- alized career development support to outstanding faculty, especially from underrepresented groups; 2) to sup- port innovative, high-impact multidisciplinary pilot projects; 3) to provide expertise and resources for culturally- sensitive measurement and analysis of cognitive risk factors in older Hispanics, including behavioral, neuro- psychological, neuroimaging, and cardiovascular and genetic traits; and 4) to create the necessary expertise and resources to establish longitudinal research cohorts of older Hispanics and their families. We will achieve these aims through the creation of 4 Cores (Administrative; Research Education; Analysis; and Community Liaison/Recruitment) to support AD research. The Center will build upon the experience of investigators at the UTRGV Institute of Neuroscience and collaborators at the South Texas Diabetes & Obesity Institute, and Washington University's AD Research Center.

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