Mentoring patient-oriented research on the health consequences of polydrug use

摘要 博士Elise Riley是哈佛大学艾滋病毒、传染病和全球医学系的教授， 加州大学旧金山分校弗朗西斯科。作为一名流行病学家，她已经指导了57名 博士后研究员和早期职业教师在她的职业生涯，同时领导 研究的重点是艾滋病毒和吸毒对健康的影响。她目前由 NIDA将进行一项关于多种药物使用、病毒载量和炎症影响的研究 艾滋病毒感染者的小血管疾病。在这里，她提出了一个扩展的 父母的研究，包括措施的色氨酸cataline，这将提供一个更好的 脑血管功能障碍的认识，通过考虑多种 生理途径。在这次扩大的调查中，莱利博士将继续成长， 改善她个人指导计划的内容。与此同时，她将与 UCSF艾滋病研究中心（CFAR）创建一个新的虚拟指导模块， 现有的CFAR指导计划。拟议的活动将提供 为早期患者提供以患者为导向的研究和职业发展方面的多种培训机会 职业调查员

ABSTRACT Dr. Elise Riley is a Professor in the Division of HIV, Infectious Diseases and Global Medicine at the University of California, San Francisco. Trained as an epidemiologist, she has mentored 57 postdoctoral fellows and early-career faculty throughout her career while simultaneously leading research focused on the health consequences of HIV and drug use. She is currently funded by NIDA to conduct a study regarding the influences of polydrug use, viral load and inflammation on small vessel disease in people living with HIV. Here she proposes an expansion of the parent study to include measures of tryptophan catabolism, which will provide a better understanding of cerebrovascular dysfunction through the consideration of multiple physiological pathways. Within this expanded investigation, Dr. Riley will continue growing and improving the content of her individual-level mentoring program. In parallel, she will partner with the UCSF Center for AIDS Research (CFAR) to create a new virtual mentoring module within the existing CFAR mentoring program. In combination, the proposed activities will provide multiple opportunities for training in patient-oriented research and career development for early career investigators.