Prevention Research Center: Parenting Among Women Who Are Opioid Users

预防研究中心：阿片类药物使用者的女性育儿

• 批准号: 10472797
• 负责人: Philip A Fisher
• 金额: $ 77.79万
• 依托单位: UNIVERSITY OF OREGON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10472797
• 关键词: 2019-nCoV; Address; Adoption; Affect; American; Area; CLIA certified; COVID-19; COVID-19 diagnostic; COVID-19 disparity; COVID-19 health disparity; COVID-19 pandemic; COVID-19 testing; Centers for Disease Control and Prevention (U.S.); Charge; Child Rearing; Communication; Communities; Community Outreach; County; Data Collection; Data Science; Development; Diagnostic tests; Equipment and Supplies; Evaluation; Event; Family; Feedback; Foundations; Friends; Future; Genomics; Goals; Health; Health Promotion; Health behavior; Hospitals; Individual; Infection; Infrastructure; Intervention; Laboratories; Laboratory Personnel; Latinx; Latinx population; Leadership; Location; Logistics; Methods; Modeling; Molecular; Molecular Biology; Morbidity - disease rate; Motivation; Oregon; Pamphlets; Penetration; Phase; Population; Prevention; Prevention Research; Protocols documentation; Public Health; RADx Underserved Populations; Ramp; Research; Research Personnel; Research Project Grants; Resources; SARS-CoV-2 infection; Science; Scientist; Site; Structure; System; Testing; Time; Underserved Population; United States; Vaccination; Virus; Visit; Woman; Work; base; behavior test; burden of illness; community based participatory research; community engagement; design; efficacious intervention; experience; health disparity; health literacy; implementation science; improved; laboratory experience; laboratory facility; mortality; operation; opioid user; outreach; outreach services; pandemic disease; programs; psychoeducation; randomized trial; recruit; research study; respiratory; response; scale up; social determinants; substance use; testing uptake; tool; transmission process; uptake; vulnerable community

PROJECT SUMMARY The global SARS-CoV-2 pandemic that causes the severe respiratory illness COVID-19 is the worst health crisis the United States has faced in a century. Although this highly contagious virus has infected millions of Americans already, the disease burdens are disproportionately born by historically underserved populations such as Latinx communities. Nationally, Latinx people with COVID-19 are hospitalized at four times the rate of Whites and have much higher rates of morbidity and mortality. This disparity is notable in Oregon, where the 13% of our population that is Latinx represents approximately 44% of COVID-19 cases. An urgent need exists to reach Oregon’s Latinx community with public health and prevention messages to increase testing. This project will implement a culturally-tailored community outreach and testing program to increase the reach, access, and uptake of testing in Latinx communities in Oregon. The project will bring together a world-class team of prevention scientists, public health experts, Latinx researchers, community partners, and biologists who have been working together to conduct SARS-CoV-2 diagnostic testing since March, soon after the pandemic first arrived in the U.S. This team has established a CLIA-certified laboratory and honed molecular testing protocols, hired and trained laboratory personnel and a field research team, procured diagnostic testing equipment and supplies, and partnered with county public health offices and hospitals throughout the state to conduct testing. The team also conducted a comprehensive community assessment using community-based participatory methods to gather Latinx community feedback on modes of communication, health messages, and testing protocols, and staffed multiple county-led testing sites serving Latinx communities. Using these resources and expertise as a foundation, a Sequential Multiple Armed Randomized Trial (SMART) will enable the evaluation of strategies for increasing testing rates and promoting health behaviors in Latinx communities. Specifically, culturally informed, community-oriented interventions will determine tools and best practices to increase testing rates and health behaviors. The efficacy of different types of approaches for increasing access to and utilization of testing will be evaluated. Lastly, the work will examine a set of county-level variables thought to affect communities’ abilities to sustain testing capacity. With support from a Latinx Community and Scientific Advisory Board, the project will ramp up to ultimately support 36 community testing sites across six counties in Oregon to serve Latinx communities. Over time, this project will help communities institutionalize optimal local testing frameworks supported by UO laboratory facilities for testing capacity, technical support for testing logistics, and collection of data on health behaviors, testing rates, and sustainability. The resulting structures and systems will be poised for future scale-up to other vulnerable communities and/or for other public health purposes (e.g., vaccination campaigns). If successful, this project will lead to a major reduction in COVID-19 health disparities in underserved populations.

项目摘要 导致严重呼吸道疾病COVID-19的全球SARS-CoV-2大流行是最糟糕的健康状况 这是美国世纪以来面临的最大危机。尽管这种高度传染性的病毒已经感染了数百万人， 在美国，疾病负担不成比例地由历史上服务不足的人群承担 例如拉丁裔社区。在全国范围内，患有COVID-19的拉丁裔人住院率是 白人的发病率和死亡率要高得多。这种差异在俄勒冈州尤为明显， 拉丁裔人口占我们人口的13%，占COVID-19病例的约44%。迫切需要 向俄勒冈州的拉丁裔社区提供公共卫生和预防信息，以增加检测。这 该项目将实施一个文化定制的社区推广和测试计划，以增加覆盖面， 在俄勒冈州的拉丁裔社区获得和接受测试。该项目将汇集一个世界级的 由预防科学家、公共卫生专家、Latinx研究人员、社区合作伙伴和生物学家组成的团队 他们自3月以来一直在合作进行SARS-CoV-2诊断测试， 这个团队已经建立了一个CLIA认证的实验室，并磨练了分子生物学。 测试协议，雇用和培训实验室人员和实地研究小组，采购诊断测试 设备和用品，并与全州的县公共卫生办公室和医院合作， 进行测试。该小组还利用基于社区的 参与式方法，收集拉丁社区对通信模式的反馈，健康信息， 和测试协议，并配备了多个县领导的测试站点服务拉丁社区。使用这些 以资源和专业知识为基础，序贯多组随机试验（SMART）将使 评估在拉丁裔社区提高检测率和促进健康行为的战略。 具体而言，了解文化、面向社区的干预措施将确定工具和最佳做法， 提高检测率和健康行为。不同类型的增加获得机会的办法的效力 将评估测试的有效性和利用率。最后，这项工作将审查一组县级变量 被认为会影响社区维持检测能力的能力。在拉丁裔社区的支持下， 科学咨询委员会，该项目将逐步扩大，最终支持36个社区测试地点在六个 县在俄勒冈州服务拉丁裔社区。随着时间的推移，这个项目将帮助社区 由UO实验室设施支持的最佳本地测试框架，以提高测试能力， 测试后勤，收集有关健康行为、测试率和可持续性的数据。所得 结构和系统将做好准备，以便将来扩大到其他脆弱社区和/或其他 公共卫生目的（例如，疫苗接种运动）。如果成功，该项目将导致 2019冠状病毒病在服务不足人群中的健康差距。