Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda

加强行为和社会科学研究能力，应对乌干达艾滋病毒护理和预防方面不断变化的挑战

• 批准号: 10381688
• 负责人: Carol Suzanne Camlin
• 金额: $ 30.11万
• 依托单位: MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10381688
• 关键词: Address; African; Behavior; Behavioral; Biomedical Research; Biometry; California; Caring; Collaborations; Decision Making; Degree program; Doctor of Philosophy; Epidemic; Faculty; Fellowship; Fostering; Future; HIV; Health Personnel; Health Sciences; Health Services Research; Health system; Individual; Interpersonal Relations; Intervention; Lead; Leadership; Master' s Degree; Mentors; Mentorship; Outcome; Persons; Play; Policy Maker; Prevention; Principal Investigator; Public Health; Research; Research Methodology; Research Personnel; Research Project Grants; Research Training; Role; San Francisco; Scientist; Training; Training Programs; Transferable Skills; Uganda; Universities; behavioral/social science; biomedical scientist; career; clinical epidemiology; evidence base; experience; faculty research; implementation science; insight; next generation; pragmatic implementation; pragmatic trial; programs; social; social culture; social science research; sociology/anthropology; theories; uptake

Principal Investigators /Program Directors (last first, middle): Kamya, Moses, R; Katahoire, Anne, R; Camlin, Carol, S Strengthening behavioral and social science research capacity to address evolving challenges in HIV care and prevention in Uganda Project Summary/Abstract Despite recent gains, major gaps remain to attaining optimal HIV care cascade outcomes and prevention targets in Uganda. Advances will require a deeper understanding of the challenges faced by people living with HIV and their healthcare providers, robust interventions targeted towards these challenges, and insights to advance uptake of biomedical preventions; behavioral and social science research (BSSR) is crucial to this endeavor. A systematic understanding of the drivers of individuals’ behavior, the role interpersonal relations play in behavioral decisions, and the influence of socio-cultural and health systems contexts on decisions and outcomes, is critical towards achieving targets and ending the epidemic. However, there are two major hurdles on the path towards inclusion of BSSR to address gaps and develop informed interventions: first, lack of systematic integration of behavioral, social science and biomedical research in pragmatic trials and implementation science research in HIV; and second, a scarcity of African-led BSSR in HIV. We propose to address these challenges by facilitating training and mentorship of Ugandan scientists in BSSR. This proposed program at Makerere University (MU), Uganda, will facilitate cross-disciplinary research that integrates BSSR into biomedical HIV interventions, and supports, trains, and mentors the next generation of African scientists to inform and lead this research. The program will: 1) provide BSSR training and mentorship to address evolving HIV care and prevention challenges; 2) strengthen the inter-disciplinarity of the MU Implementation Science (ImS) training program through inclusion of BSSR training; 3) promote the integration of BSSR in ongoing HIV ImS research projects; 4) facilitate regular interaction among BSS researchers, biomedical scientists, policy makers, and HIV program stakeholders, in order to strengthen BSSR informed evidence-based decision making; and 5) foster collaborations between BSSR faculty in Uganda and the U.S. to enable capacity-building and skills transfer. This program leverages existing collaborations among social, behavioral, and biomedical scientists at MU and its HIV programs, the University of California, San Francisco (UCSF), and Yale University. The program will provide short and long-term non-degree and degree training to strengthen BSSR expertise for trainees at diverse career stages. A pool of experienced faculty will develop and deliver training and mentored field research experiences. The proposed program will: 1) train future Ugandan leaders at MU in four-year PhD training in the health sciences focusing on BSSR; 2) support trainees in MU Master’s degree programs in Health Services Research, Clinical Epidemiology and Biostatistics, Public Health, Sociology and Anthropology with mentored BSSR opportunities; 3) offer long-term non-degree fellowship training including a UCSF online ImS course; and 4) provide intensive short courses in qualitative and mixed research methods, theory and practice of BSSR in HIV, and training in ImS. We anticipate the project to result in strong scientific leadership and expertise in BSSR in HIV in Uganda. 1

首席研究员/项目总监（最后一位，中间）：Kamya, Moses, R；卡塔霍尔，安妮，R；卡罗尔·S·卡姆林 加强行为和社会科学研究能力，应对艾滋病毒不断变化的挑战 乌干达的护理和预防 项目概要/摘要 尽管最近取得了进展，但在实现最佳艾滋病毒护理级联结果和预防方面仍存在重大差距 目标是乌干达。进步需要更深入地了解患有这种疾病的人们所面临的挑战 艾滋病毒及其医疗保健提供者、针对这些挑战的强有力的干预措施以及对 提前采用生物医学预防措施；行为和社会科学研究（BSSR）对此至关重要 努力。系统地了解个人行为的驱动因素、人际关系的作用 行为决策中的作用，以及社会文化和卫生系统背景对决策和决策的影响 成果，对于实现目标和结束疫情至关重要。然而，有两个主要障碍 在纳入 BSSR 以弥补差距并制定知情干预措施的道路上：首先，缺乏 在务实试验中系统地整合行为、社会科学和生物医学研究 艾滋病毒的实施科学研究；其次，缺乏非洲主导的艾滋病毒 BSSR。我们建议 通过促进 BSSR 中乌干达科学家的培训和指导来应对这些挑战。 乌干达麦克雷雷大学 (MU) 的这一拟议项目将促进跨学科研究， 将 BSSR 纳入艾滋病毒生物医学干预措施中，并支持、培训和指导下一代 非洲科学家为这项研究提供信息和领导。该计划将： 1) 提供 BSSR 培训和指导 应对不断变化的艾滋病毒护理和预防挑战； 2）加强MU的跨学科性 通过纳入 BSSR 培训来实施科学 (ImS) 培训计划； 3）促进融合 BSSR 参与正在进行的 HIV IMS 研究项目； 4) 促进 BSS 研究人员之间的定期互动， 生物医学科学家、政策制定者和艾滋病毒项目利益相关者，以加强 BSSR 知情 基于证据的决策； 5) 促进乌干达和美国 BSSR 教师之间的合作 以促进能力建设和技能转让。该计划利用了社会、 密歇根大学及其艾滋病毒项目、加州大学旧金山分校的行为和生物医学科学家 （加州大学旧金山分校）和耶鲁大学。该计划将提供短期和长期的非学位和学位培训 加强不同职业阶段学员的 BSSR 专业知识。将培养和培养一批经验丰富的教师队伍 提供培训和指导的实地研究经验。拟议的计划将：1）培训未来的乌干达人 密苏里大学领导者进行为期四年的健康科学博士培训，重点关注 BSSR； 2）支持MU的学员 卫生服务研究、临床流行病学和生物统计学、公共卫生、 社会学和人类学，提供 BSSR 指导机会； 3）提供长期非学位奖学金 培训包括 UCSF 在线 ImS 课程； 4）提供定性和混合强化短期课程 HIV BSSR 的研究方法、理论和实践以及 ImS 培训。我们预计该项目将取得成果 在乌干达艾滋病毒 BSSR 领域拥有强大的科学领导力和专业知识。 1