Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men
提高男性 ART 和 PrEP 采用率的自测策略和关联激励措施
基本信息
- 批准号:10214463
- 负责人:
- 金额:$ 60.32万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-09-01 至 2024-06-30
- 项目状态:已结题
- 来源:
- 关键词:AIDS preventionAcquired Immunodeficiency SyndromeAddressAdherenceAffectAfrica South of the SaharaBehaviorBehavior TherapyBiological AssayCaringClinicCluster randomized trialCommunitiesControl GroupsCountryEpidemicFishesFoundationsGenderHIVHIV SeronegativityHIV SeropositivityHIV antiretroviralHIV riskHealthHealth Services AccessibilityHuman immunodeficiency virus testImmunoassayIncentivesIncidenceInterventionKenyaMeasuresMethodsNetwork-basedOutcomeParticipantPathway interactionsPoliciesPopulationPositioning AttributePrevalencePreventionPricePrivacyPublic HealthRandomizedResearchRiskServicesSocial NetworkTenofovirTestingTrainingUrineWomanWorkantiretroviral therapybehavior influencebehavioral economicscostfinancial incentivegroup interventionhigh riskimprovedinnovationinsightmennew technologynovel strategiespeer influencepoint of carepre-exposure prophylaxisprevention servicepromoterrecruitreferral servicesscale upscreeningself testingsexsocial stigmatesting uptaketransmission processtreatment servicesuptakevoucher
项目摘要
Project Summary
Ending the AIDS epidemic in sub-Saharan will require further engagement of men in HIV testing, prevention,
and treatment, a challenging task given that nearly 50% of HIV-positive men in many countries are unaware of
their HIV status and men have lower uptake of HIV antiretroviral therapy (ART) and pre-exposure prophylaxis
(PrEP). This study focuses on a highly mobile population of men – fishermen – in Kenya’s Lake Victoria
shoreline communities, where HIV incidence rates are extremely high. Two recent innovations – HIV self-
testing (HIVST) and social network-based interventions – hold promise for overcoming barriers to HIV testing
and linkage to services for both HIV-positive and HIV-negative men. This study seeks to determine if an HIV
status-neutral, social network-based approach, along with low-cost incentives, can promote HIV testing,
linkage to care and prevention, and better health outcomes in men. It will pursue three aims:
Aim 1: Determine whether providing HIV self-tests to network-central men for distribution to other men
in their close social networks increases men’s HIV testing uptake. We will conduct social network
mapping in study communities in Siaya Country, Kenya to identify distinct close social networks of men.
We will then randomize these social networks to intervention and control groups. Network-central, highly-
connected men in each network will be recruited as “promoters”, and receive HIVST training. Promoters in
networks assigned to the intervention will then receive self-tests for distribution to men in their networks.
Promoters in networks assigned to the control will instead distribute vouchers for free self-tests at nearby
health clinics. We hypothesize higher HIV testing among men in networks that receive the intervention.
Aim 2: Determine whether network-central promoters and small incentives can increase ART and PrEP
uptake among men. We will test whether network-central promoters can enhance linkage to ART and PrEP
after self-testing, thereby addressing a key limitation of HIVST. Promoters in the Aim 1 intervention group
will be asked to distribute information and transport vouchers for ART or PrEP to men in their networks. Our
primary hypothesis is that the intervention will result in higher rates of linkage to ART or PrEP (confirmatory
testing and ART referral for positives, and PrEP screening for negatives). We also hypothesize higher ART
and PrEP uptake within 3 months among men in social networks assigned to the intervention group.
Aim 3: Test the impact of interventions on ART or PrEP retention and adherence. We will measure 6-
and 12-month VL and tenofovir levels, using a recently-developed low-cost, point-of-care PrEP adherence
urine immunoassay. Across all aims, we will use qualitative and mixed methods to identify the pathways
of intervention action, and understand how social networks and incentives affect testing and ART and PrEP
uptake and retention. This study promises high scientific and public health impact, by testing new
approaches to improve the prevention and care cascades in high-risk, mobile men in high priority settings.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Carol Suzanne Camlin其他文献
Carol Suzanne Camlin的其他文献
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{{ truncateString('Carol Suzanne Camlin', 18)}}的其他基金
Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda
加强行为和社会科学研究能力,应对乌干达艾滋病毒护理和预防方面不断变化的挑战
- 批准号:
10872340 - 财政年份:2023
- 资助金额:
$ 60.32万 - 项目类别:
Mentoring Clinical Investigators in Patient Oriented Research on Human Mobility and HIV
指导临床研究人员进行以患者为中心的人类流动性和艾滋病毒研究
- 批准号:
10257799 - 财政年份:2021
- 资助金额:
$ 60.32万 - 项目类别:
Mentoring Clinical Investigators in Patient Oriented Research on Human Mobility and HIV
指导临床研究人员进行以患者为中心的人类流动性和艾滋病毒研究
- 批准号:
10597982 - 财政年份:2021
- 资助金额:
$ 60.32万 - 项目类别:
Mentoring Clinical Investigators in Patient Oriented Research on Human Mobility and HIV
指导临床研究人员进行以患者为中心的人类流动性和艾滋病毒研究
- 批准号:
10374173 - 财政年份:2021
- 资助金额:
$ 60.32万 - 项目类别:
Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda
加强行为和社会科学研究能力,应对乌干达艾滋病毒护理和预防方面不断变化的挑战
- 批准号:
10381688 - 财政年份:2019
- 资助金额:
$ 60.32万 - 项目类别:
Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda
加强行为和社会科学研究能力,应对乌干达艾滋病毒护理和预防方面不断变化的挑战
- 批准号:
10005514 - 财政年份:2019
- 资助金额:
$ 60.32万 - 项目类别:
Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men
提高男性 ART 和 PrEP 采用率的自测策略和关联激励措施
- 批准号:
10433985 - 财政年份:2019
- 资助金额:
$ 60.32万 - 项目类别:
Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda
加强行为和社会科学研究能力,应对乌干达艾滋病毒护理和预防方面不断变化的挑战
- 批准号:
9768612 - 财政年份:2019
- 资助金额:
$ 60.32万 - 项目类别:
Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men
提高男性 ART 和 PrEP 采用率的自测策略和关联激励措施
- 批准号:
10632006 - 财政年份:2019
- 资助金额:
$ 60.32万 - 项目类别:
Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda
加强行为和社会科学研究能力,应对乌干达艾滋病毒护理和预防方面不断变化的挑战
- 批准号:
10584483 - 财政年份:2019
- 资助金额:
$ 60.32万 - 项目类别:
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