Strengthening behavioral and social science research capacity to address the evolving challenges in HIV care and prevention in Uganda

加强行为和社会科学研究能力，应对乌干达艾滋病毒护理和预防方面不断变化的挑战

• 批准号: 10584483
• 负责人: Carol Suzanne Camlin
• 金额: $ 30.06万
• 依托单位: MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10584483
• 关键词: Address; African; Behavior; Behavioral; Biomedical Research; Biometry; California; Caring; Collaborations; Decision Making; Degree program; Doctor of Philosophy; Epidemic; Faculty; Fellowship; Fostering; Future; HIV; Health Personnel; Health Sciences; Health Services Research; Health system; Individual; Interpersonal Relations; Intervention; Lead; Leadership; Master of Science; Mentors; Mentorship; Outcome; Persons; Play; Policy Maker; Prevention; Principal Investigator; Public Health; Research; Research Methodology; Research Personnel; Research Project Grants; Research Training; Role; San Francisco; Scientist; Training; Training Programs; Uganda; Universities; behavioral and social science; biomedical scientist; career; clinical epidemiology; evidence base; experience; implementation science; insight; next generation; pragmatic implementation; pragmatic trial; programs; research faculty; skills; social; social culture; social science research; sociology/anthropology; theories; uptake

Principal Investigators /Program Directors (last first, middle): Kamya, Moses, R; Katahoire, Anne, R; Camlin, Carol, S Strengthening behavioral and social science research capacity to address evolving challenges in HIV care and prevention in Uganda Project Summary/Abstract Despite recent gains, major gaps remain to attaining optimal HIV care cascade outcomes and prevention targets in Uganda. Advances will require a deeper understanding of the challenges faced by people living with HIV and their healthcare providers, robust interventions targeted towards these challenges, and insights to advance uptake of biomedical preventions; behavioral and social science research (BSSR) is crucial to this endeavor. A systematic understanding of the drivers of individuals’ behavior, the role interpersonal relations play in behavioral decisions, and the influence of socio-cultural and health systems contexts on decisions and outcomes, is critical towards achieving targets and ending the epidemic. However, there are two major hurdles on the path towards inclusion of BSSR to address gaps and develop informed interventions: first, lack of systematic integration of behavioral, social science and biomedical research in pragmatic trials and implementation science research in HIV; and second, a scarcity of African-led BSSR in HIV. We propose to address these challenges by facilitating training and mentorship of Ugandan scientists in BSSR. This proposed program at Makerere University (MU), Uganda, will facilitate cross-disciplinary research that integrates BSSR into biomedical HIV interventions, and supports, trains, and mentors the next generation of African scientists to inform and lead this research. The program will: 1) provide BSSR training and mentorship to address evolving HIV care and prevention challenges; 2) strengthen the inter-disciplinarity of the MU Implementation Science (ImS) training program through inclusion of BSSR training; 3) promote the integration of BSSR in ongoing HIV ImS research projects; 4) facilitate regular interaction among BSS researchers, biomedical scientists, policy makers, and HIV program stakeholders, in order to strengthen BSSR informed evidence-based decision making; and 5) foster collaborations between BSSR faculty in Uganda and the U.S. to enable capacity-building and skills transfer. This program leverages existing collaborations among social, behavioral, and biomedical scientists at MU and its HIV programs, the University of California, San Francisco (UCSF), and Yale University. The program will provide short and long-term non-degree and degree training to strengthen BSSR expertise for trainees at diverse career stages. A pool of experienced faculty will develop and deliver training and mentored field research experiences. The proposed program will: 1) train future Ugandan leaders at MU in four-year PhD training in the health sciences focusing on BSSR; 2) support trainees in MU Master’s degree programs in Health Services Research, Clinical Epidemiology and Biostatistics, Public Health, Sociology and Anthropology with mentored BSSR opportunities; 3) offer long-term non-degree fellowship training including a UCSF online ImS course; and 4) provide intensive short courses in qualitative and mixed research methods, theory and practice of BSSR in HIV, and training in ImS. We anticipate the project to result in strong scientific leadership and expertise in BSSR in HIV in Uganda. 1

首席调查人员/项目主任(后一，中)：卡米亚，摩西，右；卡塔霍尔，安妮，右；卡姆林，卡罗尔，S 加强行为和社会科学研究能力，以应对艾滋病毒不断变化的挑战 乌干达的护理和预防 项目摘要/摘要 尽管最近取得了进展，但在实现最佳艾滋病毒护理级联成果和预防方面仍然存在重大差距 乌干达的目标。进步将需要更深入地理解与之生活在一起的人面临的挑战 艾滋病毒及其医疗保健提供者，针对这些挑战的强有力的干预措施，以及对 推进生物医学预防；行为和社会科学研究(BSSR)是关键 努力吧。系统地理解个人行为的驱动因素、角色、人际关系 在行为决策中发挥作用，以及社会文化和卫生系统背景对决策和 结果，对于实现目标和结束这一流行病至关重要。然而，有两个主要障碍 在纳入BSSR以弥补差距和制定知情干预措施的道路上：第一，缺乏 在务实试验中系统地整合行为、社会科学和生物医学研究 第一，艾滋病毒方面的实施科学研究；第二，在艾滋病毒方面缺乏由非洲领导的BSSR。我们建议 通过促进在BSSR对乌干达科学家的培训和指导来应对这些挑战。 这项在乌干达Makerere大学(MU)拟议的项目将促进跨学科研究， 将BSSR整合到生物医学艾滋病毒干预中，并支持、培训和指导下一代 非洲科学家为这项研究提供信息并领导这项研究。该计划将：1)提供BSSR培训和指导 应对不断变化的艾滋病毒护理和预防挑战；2)加强医疗机构的跨学科 实施科学(IMS)培训计划，纳入BSSR培训；3)促进一体化 在正在进行的艾滋病毒/艾滋病综合管理系统研究项目中促进生物科学研究；4)促进生物科学研究人员之间的定期互动， 生物医学科学家、政策制定者和艾滋病毒项目利益攸关方，以加强BSSR的知情 基于证据的决策；5)促进乌干达和美国BSSR教职员工之间的合作。 促进能力建设和技能转让。该计划利用现有的社交、 加州大学旧金山分校行为和生物医学科学家及其艾滋病毒项目 (加州大学旧金山分校)和耶鲁大学。该计划将为以下人员提供短期和长期非学位和学位培训 为处于不同职业阶段的学员加强BSSR专业知识。将培养和培养一批经验丰富的教职员工 提供培训和有指导的实地研究经验。拟议的计划将：1)培养未来的乌干达人 墨尔本大学领导参加为期四年的健康科学博士培训，重点是BSSR；2)支持墨尔本大学的受训人员 卫生服务研究、临床流行病学和生物统计学、公共卫生、 社会学和人类学，有指导的BSSR机会；3)提供长期非学位奖学金 培训，包括加州大学旧金山分校的在线IMS课程；以及4)提供定性和混合的短期强化课程 艾滋病毒BSSR的研究方法、理论和实践，以及IMS的培训。我们期待这个项目能取得成果。 在乌干达艾滋病毒BSSR领域具有强大的科学领导力和专业知识。 1