Core-008

核心008

• 批准号: 10414775
• 负责人: RONALD J. SOKOL
• 金额: $ 33.52万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-11-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10414775
• 关键词: Award; Capital Financing; Clinical; Clinical Sciences; Collaborations; Colorado; Course Content; Development; Economic Development; Ecosystem; Education; Entrepreneurship; Faculty; Fostering; Funding; Goals; Health; Infrastructure; Innovation Corps; Institutes; International; Investments; Lead; Mentorship; National Center for Advancing Translational Sciences; Process; Resources; Rewards; Science; Services; Trainers Training; Training; Training Programs; Translational Research; Translations; United States National Institutes of Health; Universities; career; commercialization; experience; graduate student; innovation; product development; programs; training opportunity

The Innovation Ecosystem (Partnering for Innovation Value Optimization and Accelerated Translation [PIVOT]) program will embrace innovation and commercial translation to advance biomedical discoveries into the marketplace. Through this Optional Function of the CCTSI, we will develop and sustain an innovation program to educate, train and develop our workforce in commercial value translation; to support the technical development of commercializable innovation; and to demonstrate value and health impact of clinical and translational science innovation by providing access to accelerator venture capital funding, domain expertise, and commercialization mentorship. The overall goal of PIVOT is to provide a seamless, multi-level investigatorfacing infrastructure supporting the commercialization and product development of innovative ideas and, in the process, support and academically reward entrepreneurship. We will achieve these goals through the following specific aims: Aim 1: Workforce. Catalyze an academic entrepreneur culture and workforce by (a) disseminating and expanding the reach of bio-entrepreneurship training opportunities, (b) fostering entrepreneurial networking, and (c) demonstrating career trajectories for faculty and graduate students who are clinical and translational science innovators. Aim 2: Development. Accelerate the development of commercializable innovation through customer discovery by Innovation-Corps (I-Corps™) teams and promote combined usage of I-Corps and Team Science training for innovation teams receiving CCTSI pilot awards. Aim 3: Demonstrate impact. Accelerate health impact demonstration through active navigation to resources within the CCTSI ecosystem which provide commercialization mentorship, domain expertise, and accelerator funding. The CCTSI PIVOT program will serve as an integrator-navigator and resource multiplier to expand and extend the reach of entrepreneurial investment and infrastructure support provided by University of Colorado and Colorado State University and the Colorado Office of Economic Development and International Trade. PIVOT will also capitalize on two unique NIH workforce training programs in Colorado: the Broadening Experiences in Scientific Training (BEST) award for graduate trainees in clinical and translational sciences; and the I-Corps™ Train-the-Trainer program at NCATS to develop a scalable short-course curriculum and common metrics adapted to the needs of clinical and translational science programs that will be disseminated across the CTSA consortium. In collaboration with an extensive network of state-wide, national and institutional innovation and entrepreneurship partnerships, PIVOT will lead a major academic shift within the CCTSI ecosystem by embracing innovation and commercial translation to advance biomedical discoveries into the marketplace. We will foster a culture that supports startup incubation and provides education and practical training to help academic ventures develop commercially-viable products and services.

创新生态系统（合作创新价值优化和加速转化） [PIVOT]）计划将拥抱创新和商业转化，将生物医学发现推进到 市场。通过 CCTSI 的这一可选功能，我们将开发和维持创新 教育、培训和发展我们的商业价值翻译员工队伍的计划；以支持技术 商业化创新的发展；并证明临床和健康的价值和影响 通过提供加速器风险投资资金、领域专业知识、 和商业化指导。 PIVOT 的总体目标是提供一个无缝的、多层次的面向调查人员的平台 支持创新理念商业化和产品开发的基础设施， 过程、支持和学术奖励创业精神。我们将通过以下方式实现这些目标 具体目标： 目标 1：劳动力。通过以下方式促进学术企业家文化和劳动力：（a）传播 扩大生物创业培训机会的范围，(b) 促进创业网络， (c) 展示临床和转化教师和研究生的职业轨迹 科学创新者。目标2：发展。通过以下方式加速商业化创新的发展 Innovation-Corps (I-Corps™) 团队发现客户并促进 I-Corps 和 Team 的结合使用 为获得 CCTSI 试点奖项的创新团队提供科学培训。目标 3：展示影响力。加速 通过主动导航 CCTSI 生态系统内的资源来展示健康影响，这些资源提供 商业化指导、领域专业知识和加速器资金。 CCTSI PIVOT 计划将服务于 作为整合者、领航者和资源倍增器，扩大和延伸创业投资的范围 科罗拉多大学、科罗拉多州立大学和科罗拉多大学提供的基础设施支持 经济发展和国际贸易办公室。 PIVOT 还将利用 NIH 的两名独特劳动力 科罗拉多州的培训计划：毕业生科学培训拓宽经验 (BEST) 奖 临床和转化科学的实习生；以及 NCATS 的 I-Corps™ 培训师培训计划，以开发 适应临床和转化需求的可扩展的短期课程和通用指标 将在 CTSA 联盟中传播的科学计划。与广泛的合作 PIVOT 将在全州、国家和机构的创新和创业合作伙伴关系网络中引领 通过拥抱创新和商业翻译，CCTSI 生态系统内发生了重大学术转变 将生物医学发现推向市场。我们将培育支持初创企业孵化的文化 并提供教育和实践培训，帮助学术企业开发商业上可行的产品 和服务。