Core-008

核心008

• 批准号: 10414775
• 负责人: RONALD J. SOKOL
• 金额: $ 33.52万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-11-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10414775
• 关键词: Award; Capital Financing; Clinical; Clinical Sciences; Collaborations; Colorado; Course Content; Development; Economic Development; Ecosystem; Education; Entrepreneurship; Faculty; Fostering; Funding; Goals; Health; Infrastructure; Innovation Corps; Institutes; International; Investments; Lead; Mentorship; National Center for Advancing Translational Sciences; Process; Resources; Rewards; Science; Services; Trainers Training; Training; Training Programs; Translational Research; Translations; United States National Institutes of Health; Universities; career; commercialization; experience; graduate student; innovation; product development; programs; training opportunity

The Innovation Ecosystem (Partnering for Innovation Value Optimization and Accelerated Translation [PIVOT]) program will embrace innovation and commercial translation to advance biomedical discoveries into the marketplace. Through this Optional Function of the CCTSI, we will develop and sustain an innovation program to educate, train and develop our workforce in commercial value translation; to support the technical development of commercializable innovation; and to demonstrate value and health impact of clinical and translational science innovation by providing access to accelerator venture capital funding, domain expertise, and commercialization mentorship. The overall goal of PIVOT is to provide a seamless, multi-level investigatorfacing infrastructure supporting the commercialization and product development of innovative ideas and, in the process, support and academically reward entrepreneurship. We will achieve these goals through the following specific aims: Aim 1: Workforce. Catalyze an academic entrepreneur culture and workforce by (a) disseminating and expanding the reach of bio-entrepreneurship training opportunities, (b) fostering entrepreneurial networking, and (c) demonstrating career trajectories for faculty and graduate students who are clinical and translational science innovators. Aim 2: Development. Accelerate the development of commercializable innovation through customer discovery by Innovation-Corps (I-Corps™) teams and promote combined usage of I-Corps and Team Science training for innovation teams receiving CCTSI pilot awards. Aim 3: Demonstrate impact. Accelerate health impact demonstration through active navigation to resources within the CCTSI ecosystem which provide commercialization mentorship, domain expertise, and accelerator funding. The CCTSI PIVOT program will serve as an integrator-navigator and resource multiplier to expand and extend the reach of entrepreneurial investment and infrastructure support provided by University of Colorado and Colorado State University and the Colorado Office of Economic Development and International Trade. PIVOT will also capitalize on two unique NIH workforce training programs in Colorado: the Broadening Experiences in Scientific Training (BEST) award for graduate trainees in clinical and translational sciences; and the I-Corps™ Train-the-Trainer program at NCATS to develop a scalable short-course curriculum and common metrics adapted to the needs of clinical and translational science programs that will be disseminated across the CTSA consortium. In collaboration with an extensive network of state-wide, national and institutional innovation and entrepreneurship partnerships, PIVOT will lead a major academic shift within the CCTSI ecosystem by embracing innovation and commercial translation to advance biomedical discoveries into the marketplace. We will foster a culture that supports startup incubation and provides education and practical training to help academic ventures develop commercially-viable products and services.

创新生态系统（创新价值优化和加速翻译合作 [Pivot]）计划将采用创新和商业翻译，以将生物医学发现推向 市场。通过CCTSI的这一可选功能，我们将开发和维持创新 教育，培训和发展我们的商业价值翻译劳动力的计划；支持技术 开发可商业化的创新；并展示临床和 转化科学创新通过提供加速器风险投资，领域专业知识的访问权限， 和商业化心态。枢轴的总体目标是提供无缝的多层次研究员 支持创新思想的商业化和产品开发的基础设施，并在 过程，支持并准确奖励企业家精神。我们将通过以下来实现这些目标 具体目的：目标1：劳动力。催化（a）传播的学术企业家文化和劳动力 并扩大生物企业家培训机会的影响力，（b）促进企业家网络， （c）为临床和翻译的教师和研究生展示职业轨迹 科学创新者。目标2：发展。加速通过商业化创新的发展 Innovation-Corps（I-Corps™）团队的客户发现，并促进了I-Corps和团队的综合使用 获得CCTSI试点奖的创新团队的科学培训。目标3：展示影响。加速 通过主动导航到CCTSI生态系统中的资源，健康影响示范 商业化精神验证，领域专业知识和加速器资金。 CCTSI枢轴计划将服务 作为集成商 - 武器和资源乘数，以扩展和扩展企业家投资的影响力 科罗拉多大学和科罗拉多州立大学和科罗拉多州提供的基础设施支持 经济发展和国际贸易办公室。 Pivot还将利用两个独特的NIH劳动力 科罗拉多州的培训计划：研究生的科学培训（最佳）奖的扩大经验 临床和翻译科学学员；以及NCAT的I-Corps™火车训练计划 适合临床和翻译需求的可扩展的短道课程和常见的指标 将在整个CTSA财团中传播的科学计划。与广泛的合作 国家，国家和机构创新与企业家伙伴关系网络，Pivot将领导 CCTSI生态系统内的重大学术转变，通过拥抱创新和商业翻译为 将生物医学的发现推向市场。我们将培养一种支持启动孵化的文化 并提供教育和实践培训，以帮助学术企业开发商业可行的产品 和服务。