Colorado Clinical and Translational Sciences Institute: UL1 Diversity KL2 Supplement

科罗拉多临床和转化科学研究所：UL1 多样性 KL2 补充材料

• 批准号: 10288971
• 负责人: RONALD J. SOKOL
• 金额: $ 14.58万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10288971
• 关键词: Academic Medical Centers; Address; Affect; African American; Amputation; Antihypertensive Agents; Atlases; Award; Behavior; Belief; Biomedical Research; COVID-19; COVID-19 patient; Caring; Child; Clinical; Clinical Sciences; Collaborations; Colorado; Communication; Communities; Computer software; Data; Development; Diagnosis; Disease; Disease Management; Drug Prescriptions; Elderly; Ensure; Environment; Ethnic Origin; Faculty; Feedback; Fostering; Funding; Future; Goals; Grant; Grant Review; Guidelines; Health; Health Services Accessibility; Health system; Healthcare; Healthcare Systems; Hispanic Americans; Hispanics; Home; Hospitals; Individual; Informatics; Infrastructure; Institutes; Interdisciplinary Study; Intervention; Interview; K-Series Research Career Programs; Knowledge; Learning; Lower Extremity; Measures; Medical; Medical center; Mentors; Methodology; Methods; Minority; NCI Scholars Program; Not Hispanic or Latino; Nursery Schools; Nursing Faculty; Outcome; Parents; Patient Care; Patient Recruitments; Patient-Focused Outcomes; Patients; Perception; Peripheral arterial disease; Pharmaceutical Preparations; Phase; Population; Positioning Attribute; Preventive treatment; Principal Investigator; Procedures; Process; Program Development; Program Reviews; Protocols documentation; Provider; Public Health; Race; Rare Diseases; Recommendation; Research; Research Personnel; Research Proposals; Research Training; Resources; Risk; Risk Factors; Role; Safety; Science; Self Management; Services; Special Population; Surveys; Testing; Training; Training Support; Training and Education; Translational Research; Translations; Underserved Population; United States National Institutes of Health; Universities; Work; adherence rate; adverse outcome; care delivery; care outcomes; career; career development; community engagement; community organizations; design; disparity elimination; effectiveness implementation study; effectiveness implementation trial; ethnic minority population; evidence base; experience; formative assessment; health care availability; health care delivery; health care disparity; health care settings; health difference; health disparity; health inequalities; implicit bias; improved; innovation; medical specialties; medication compliance; meetings; member; modifiable behavior; novel; pandemic disease; patient population; peer; programs; racial and ethnic; racial and ethnic disparities; racial difference; research and development; risk perception; safety net; social health determinants; therapy design; therapy development; translational scientist; treatment disparity

Principal Investigator (Last, first, middle): Sokol, Ronald (Diversity Candidate: McNeal, Demetria, M) SUMMARY Abstract of NCATS-Funded UL1 Project Funded by NIH in 2008, 2013 and 2018 the Colorado Clinical and Translational Sciences Institute (CCTSI) at the University of Colorado Anschutz Medical Campus (CUAMC) has transformed and improved the biomedical; research and training enterprise in the Colorado region and accelerated and catalyzed the translation of discoveries into improved patient care and public health. The CCTSI, a partnership of CUAMC, CU Boulder, Colorado State University, six hospitals and 20 community organizations, has established new infrastructure, streamlined processes and expanded existing resources and services for investigators and stakeholders; tripled the number of training and education programs supporting development of a translational workforce; promoted team science and interdisciplinary research; established an extensive community engagement program; created an academic home for clinical & translational scientists and trainees; and actively engaged in CTSA network activities. CCTSI has five overall strategic goals: Goal 1: Develop, educate and sustain a diverse translational science workforce to ensure the highest research innovation, quality and safety. Goal 2: Create a translational research environment in which team science and local and national collaboration are facilitated, supported and valued. Goal 3: Engage local and national communities and stakeholders in all phases of the translational research process. Goal 4: Create novel methodologies and resources to support and integrate research in special populations, including children, the elderly, the underserved and those with rare diseases. Goal 5: Further innovate and streamline our processes and enhance our informatics capacity for research start-up, implementation and oversight to promote quality, efficiency, & safety of our research and our active participation in the national CTSA Trial Innovation Network. Dr. McNeal's proposal capitalizes on CCTSI's goals one and four and their accompanying resources in the following ways. First, to support attainment of CCTSI goal 1, the CCTSI has established new programs and offers resources designed to support the development of early stage career faculty. Existing programs and resources create the ideal environment for Dr. McNeal, a junior and minority faculty member, to advance and thrive as an independent scholar. To prepare for this submission, Dr. McNeal has already participated in one CCTSI sponsored program (CCTSI Research Studio) in which a team of interdisciplinary senior scholars reviewed this project proposal and provided feedback to further refine the research question and methodology. Dr. McNeal has been competitively selected to participate in two research and career development programs: The National Institutes of Health Programs to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE) and the CCTSI-sponsored Clinical Faculty Scholars Program. Additionally, Dr. McNeal has completed two Atlas.ti courses to learn software management for qualitative data. To support learning opportunities identified in the Mentoring Plan (see figure 2), Dr. McNeal will have access to both coursework and hands on experiences over the course of the award period. Specific CCTSI training includes course work through the Clinical Sciences Graduate Program, the KL2 career in progress monthly meetings, the Pre-K grant review program and the Research Studio. Additional CCTSI trainings that Dr. McNeal will use include Regulatory Knowledge and Support, Protocol Submission and Recruiting Participants (see table 3). Second, in alignment with CCTSI goal 4, the study has an explicit focus on underserved populations. Dr. McNeal is investigating Black and Hispanic American populations. The project will identify underlying clinician and patient related factors that contribute to health disparities in outcomes and health inequities in care delivery among African American and Hispanic patients with peripheral artery disease (PAD). This is an important and novel project that is the first step in addressing health disparities and fits very well within the Parent U1 grant and the functions of the CCTSI.

主要研究者（最后、第一、中间）：索科尔、罗纳德（多样性候选人：McNeal、Demetria、M） 总结 NCATS-Funded UL1项目摘要 由NIH在2008年，2013年和2018年资助的科罗拉多临床和转化科学研究所（CCTSI）， 科罗拉多大学安舒茨医学院（CUAMC）已经改变和改善了生物医学; 研究和培训企业在科罗拉多地区，并加速和催化翻译 改善病人护理和公共卫生的新发现。CCTSI是CUAMC，CU Boulder， 科罗拉多州立大学、6家医院和20个社区组织，建立了新的基础设施， 简化程序，扩大现有资源和为调查人员和利益攸关方提供的服务; 将支持翻译工作队伍发展的培训和教育项目数量增加两倍; 促进团队科学和跨学科研究;建立广泛的社区参与 计划;为临床和转化科学家和学员创建了一个学术之家;并积极参与 CTSA网络活动。CTSI有五个总体战略目标： 目标1：发展、教育和维持多样化的转化科学工作队伍，以确保最高水平的研究 创新、质量和安全。 目标2：创造一个转化研究的环境，在其中团队科学和地方和国家合作 得到促进、支持和重视。 目标3：让地方和国家社区及利益攸关方参与转化研究的所有阶段 过程 目标4：创造新的方法和资源，以支持和整合对特殊人群的研究， 包括儿童、老年人、得不到充分服务的人和患有罕见疾病的人。 目标5：进一步创新和精简我们的程序，加强我们的研究信息能力 启动，实施和监督，以提高质量，效率，我们的研究和我们的积极安全 参与国家CTSA试验创新网络。 博士McNeal的提案利用了CCTSI的目标一和四及其在 遵循方式。首先，为了支持实现CCTSI目标1，CCTSI制定了新的计划， 提供旨在支持早期职业教师发展的资源。现有的程序和 资源为麦克尼尔博士，一个初级和少数民族教师创造了理想的环境，以促进和 作为一个独立的学者。为了准备这次提交，McNeal博士已经参加了一个 CCTSI赞助的项目（CCTSI研究工作室）中，跨学科的高级学者团队 审查了该项目提案并提供反馈以进一步完善研究问题和方法。 博士麦克尼尔已竞争性地选择参加两个研究和职业发展计划： 美国国立卫生研究院计划增加与健康相关的个人之间的多样性 研究（PRIDE）和CCTSI赞助的临床教师学者计划。此外，McNeal博士 完成了两个Atlas. ti课程，学习质量数据软件管理。来支持学习 机会中确定的指导计划（见图2），麦克尼尔博士将有机会获得这两门课程 并在获奖期间亲身体验。具体的CCTSI培训包括课程工作 通过临床科学研究生课程，KL2职业发展每月会议，Pre-K 资助审查计划和研究工作室。McNeal博士将使用的其他CCTSI培训包括 法规知识和支持、方案提交和招募参与者（见表3）。二是 该研究与《儿童与社会服务倡议》的目标4相一致，明确关注得不到充分服务的人口。麦克尼尔医生 调查黑人和西班牙裔美国人该项目将确定潜在的临床医生和 与患者相关的因素，导致结果中的健康差异和护理提供中的健康不平等 非裔美国人和西班牙裔外周动脉疾病（PAD）患者。这是一个重要的， 一个新颖的项目，这是解决健康差距的第一步，非常适合父母U1赠款 以及CCTSI的功能。