Colorado Clinical and Translational Sciences Institute: UL1 Diversity KL2 Supplement

科罗拉多临床和转化科学研究所：UL1 多样性 KL2 补充材料

• 批准号: 10288971
• 负责人: RONALD J. SOKOL
• 金额: $ 14.58万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10288971
• 关键词: Academic Medical Centers; Address; Affect; African American; Amputation; Antihypertensive Agents; Atlases; Award; Behavior; Belief; Biomedical Research; COVID-19; COVID-19 patient; Caring; Child; Clinical; Clinical Sciences; Collaborations; Colorado; Communication; Communities; Computer software; Data; Development; Diagnosis; Disease; Disease Management; Drug Prescriptions; Elderly; Ensure; Environment; Ethnic Origin; Faculty; Feedback; Fostering; Funding; Future; Goals; Grant; Grant Review; Guidelines; Health; Health Services Accessibility; Health system; Healthcare; Healthcare Systems; Hispanic Americans; Hispanics; Home; Hospitals; Individual; Informatics; Infrastructure; Institutes; Interdisciplinary Study; Intervention; Interview; K-Series Research Career Programs; Knowledge; Learning; Lower Extremity; Measures; Medical; Medical center; Mentors; Methodology; Methods; Minority; NCI Scholars Program; Not Hispanic or Latino; Nursery Schools; Nursing Faculty; Outcome; Parents; Patient Care; Patient Recruitments; Patient-Focused Outcomes; Patients; Perception; Peripheral arterial disease; Pharmaceutical Preparations; Phase; Population; Positioning Attribute; Preventive treatment; Principal Investigator; Procedures; Process; Program Development; Program Reviews; Protocols documentation; Provider; Public Health; Race; Rare Diseases; Recommendation; Research; Research Personnel; Research Proposals; Research Training; Resources; Risk; Risk Factors; Role; Safety; Science; Self Management; Services; Special Population; Surveys; Testing; Training; Training Support; Training and Education; Translational Research; Translations; Underserved Population; United States National Institutes of Health; Universities; Work; adherence rate; adverse outcome; care delivery; care outcomes; career; career development; community engagement; community organizations; design; disparity elimination; effectiveness implementation study; effectiveness implementation trial; ethnic minority population; evidence base; experience; formative assessment; health care availability; health care delivery; health care disparity; health care settings; health difference; health disparity; health inequalities; implicit bias; improved; innovation; medical specialties; medication compliance; meetings; member; modifiable behavior; novel; pandemic disease; patient population; peer; programs; racial and ethnic; racial and ethnic disparities; racial difference; research and development; risk perception; safety net; social health determinants; therapy design; therapy development; translational scientist; treatment disparity

Principal Investigator (Last, first, middle): Sokol, Ronald (Diversity Candidate: McNeal, Demetria, M) SUMMARY Abstract of NCATS-Funded UL1 Project Funded by NIH in 2008, 2013 and 2018 the Colorado Clinical and Translational Sciences Institute (CCTSI) at the University of Colorado Anschutz Medical Campus (CUAMC) has transformed and improved the biomedical; research and training enterprise in the Colorado region and accelerated and catalyzed the translation of discoveries into improved patient care and public health. The CCTSI, a partnership of CUAMC, CU Boulder, Colorado State University, six hospitals and 20 community organizations, has established new infrastructure, streamlined processes and expanded existing resources and services for investigators and stakeholders; tripled the number of training and education programs supporting development of a translational workforce; promoted team science and interdisciplinary research; established an extensive community engagement program; created an academic home for clinical & translational scientists and trainees; and actively engaged in CTSA network activities. CCTSI has five overall strategic goals: Goal 1: Develop, educate and sustain a diverse translational science workforce to ensure the highest research innovation, quality and safety. Goal 2: Create a translational research environment in which team science and local and national collaboration are facilitated, supported and valued. Goal 3: Engage local and national communities and stakeholders in all phases of the translational research process. Goal 4: Create novel methodologies and resources to support and integrate research in special populations, including children, the elderly, the underserved and those with rare diseases. Goal 5: Further innovate and streamline our processes and enhance our informatics capacity for research start-up, implementation and oversight to promote quality, efficiency, & safety of our research and our active participation in the national CTSA Trial Innovation Network. Dr. McNeal's proposal capitalizes on CCTSI's goals one and four and their accompanying resources in the following ways. First, to support attainment of CCTSI goal 1, the CCTSI has established new programs and offers resources designed to support the development of early stage career faculty. Existing programs and resources create the ideal environment for Dr. McNeal, a junior and minority faculty member, to advance and thrive as an independent scholar. To prepare for this submission, Dr. McNeal has already participated in one CCTSI sponsored program (CCTSI Research Studio) in which a team of interdisciplinary senior scholars reviewed this project proposal and provided feedback to further refine the research question and methodology. Dr. McNeal has been competitively selected to participate in two research and career development programs: The National Institutes of Health Programs to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE) and the CCTSI-sponsored Clinical Faculty Scholars Program. Additionally, Dr. McNeal has completed two Atlas.ti courses to learn software management for qualitative data. To support learning opportunities identified in the Mentoring Plan (see figure 2), Dr. McNeal will have access to both coursework and hands on experiences over the course of the award period. Specific CCTSI training includes course work through the Clinical Sciences Graduate Program, the KL2 career in progress monthly meetings, the Pre-K grant review program and the Research Studio. Additional CCTSI trainings that Dr. McNeal will use include Regulatory Knowledge and Support, Protocol Submission and Recruiting Participants (see table 3). Second, in alignment with CCTSI goal 4, the study has an explicit focus on underserved populations. Dr. McNeal is investigating Black and Hispanic American populations. The project will identify underlying clinician and patient related factors that contribute to health disparities in outcomes and health inequities in care delivery among African American and Hispanic patients with peripheral artery disease (PAD). This is an important and novel project that is the first step in addressing health disparities and fits very well within the Parent U1 grant and the functions of the CCTSI.

首席研究员（最后、第一、中间）：Sokol、Ronald（多元化候选人：McNeal、Demetria、M） 概括 NCATS资助的UL1项目摘要 2008 年、2013 年和 2018 年由 NIH 资助科罗拉多临床和转化科学研究所 (CCTSI) 科罗拉多大学安舒茨医学校区 (CUAMC) 改变并改进了生物医学； 科罗拉多地区的研究和培训企业，并加速和催化了 改善患者护理和公共卫生的发现。 CCTSI 是 CUAMC、CU Boulder 的合作伙伴， 科罗拉多州立大学、六家医院和20个社区组织，建立了新的基础设施， 为调查人员和利益相关者简化流程并扩大现有资源和服务； 支持转化型劳动力发展的培训和教育项目数量增加了两倍； 促进团队科学和跨学科研究；建立了广泛的社区参与 程序;为临床和转化科学家和实习生创建了一个学术之家；并积极投身于 CTSA 网络活动。 CCTSI 有五个总体战略目标： 目标 1：培养、教育和维持多元化的转化科学劳动力，以确保最高水平的研究 创新、质量和安全。 目标 2：创建一个转化研究环境，在其中进行团队科学以及地方和国家合作 得到促进、支持和重视。 目标 3：让地方和国家社区以及利益相关者参与转化研究的所有阶段 过程。 目标 4：创建新的方法和资源来支持和整合特殊人群的研究， 包括儿童、老年人、服务不足的人和患有罕见疾病的人。 目标 5：进一步创新和简化我们的流程，增强我们的信息学研究能力 启动、实施和监督，以提高我们研究和活动的质量、效率和安全性 参与国家 CTSA 试验创新网络。 McNeal 博士的提案利用了 CCTSI 的目标一和四以及它们在 以下方式。首先，为了支持 CCTSI 目标 1 的实现，CCTSI 制定了新的计划和 提供旨在支持早期职业教师发展的资源。现有计划和 资源为麦克尼尔博士（一名初级和少数族裔教员）创造了理想的环境，以推动和发展 作为一名独立学者茁壮成长。为了准备本次提交，麦克尼尔博士已经参加了一项 CCTSI赞助项目（CCTSI研究工作室），由跨学科资深学者组成的团队 审查了该项目提案并提供反馈以进一步完善研究问题和方法。 麦克尼尔博士被竞争性地选拔参加两个研究和职业发展项目： 美国国立卫生研究院旨在增加从事健康相关工作的个人多样性的计划 研究 (PRIDE) 和 CCTSI 赞助的临床教师学者计划。此外，麦克尼尔博士还 完成了两门 Atlas.ti 课程，学习定性数据的软件管理。支持学习 指导计划中确定的机会（见图 2），麦克尼尔博士将有权访问这两个课程 并在颁奖期间积累实践经验。具体的 CCTSI 培训包括课程作业 通过临床科学研究生计划、KL2 职业发展月度会议、Pre-K 拨款审查计划和研究工作室。 McNeal 博士将使用的其他 CCTSI 培训包括 监管知识和支持、方案提交和招募参与者（见表 3）。其次，在 与 CCTSI 目标 4 一致，该研究明确关注服务不足的人群。麦克尼尔博士是 调查黑人和西班牙裔美国人。该项目将确定潜在的临床医生和 导致结果健康差异和护理服务健康不平等的患者相关因素 患有外周动脉疾病（PAD）的非裔美国人和西班牙裔患者。这是一个重要且 新颖的项目是解决健康差异的第一步，非常适合家长 U1 补助金 以及 CCTSI 的职能。