Core-003

翻译工作包括提议的CCTSI的两个关键职能：翻译 劳动力发展计划(TWD)和试点翻译和临床研究计划(PTC)。 临床和转化科学的成功需要具有互补专业知识的个人的团队合作。 TWD计划提出以高绩效为导向、基于能力的培训和准备，以创造 一支多元化、才华横溢、尽职尽责的员工队伍，能够加快临床转化科学的进程 改善社会健康状况。TWD将沿着一系列计划提供教育和培训 从学生和实习生开始，扩展到包括所有教职员工级别的职业发展(教师 教授)和工作人员(从事临床或转化性研究的任何人)。我们将实现这些目标 通过以下具体目标：目标1：培养和留住一支高素质的跨学科团队 员工队伍准备进行严格的临床转化性研究(CTR)。目标1.1。确保整个 CTR工作人员接受良好临床实践、负责任的研究行为、 研究道德和法规遵从性。目标1.2。作为团队提高CCTSI的员工工作效率 通过在团队科学、领导力和指导方面提供专业发展倡议。目标1.3。 开发、试点和评估专业研究助理的职业阶梯，以规范专业 在他们的职业轨迹中的发展和能力。目标1.4。弥合学习差距 CCTSI员工通过提供大数据/信息学、企业家精神和 传播和实施科学。PTC计划将加快临床和翻译研究 通过一项战略性试点拨款计划，旨在为创新想法、研究方法和 CCTSI工作人员的协作。该方案将重点支持新的研究，将催化 将科学发现转化为治疗方法，开发新的方法来推进翻译 科学，促进社区参与翻译和团队科学，并促进年轻人的发展 临床和转化性研究的研究人员。我们将通过以下具体措施实现这些目标 目标：目标2：实施全面的试点翻译和临床研究计划(PTC)以加快 CCTSI合作伙伴分支机构中的高质量协作CTR。目标3：进行严格、透明的行为 对PTC申请进行同行审查，以确保只有潜在影响最大的项目才会得到 这个项目。目标4：建立和实施将用于监测临时技术合作影响的指标。这个 PTC将提供机会，解决CCTSI的具体优先事项，并为创新想法和 新技术的发展。该计划将促进所有学科的研究，并将优先考虑 促进翻译科学发展的研究建议。将通过NCATS和NCATS监控计划影响 共同指标以及为满足当地PTC的需求而制定的指标。

Translational Endeavors encompasses two critical functions for the proposed CCTSI: the Translational Workforce Development Program (TWD) and the Pilot Translational and Clinical Studies Program (PTC). Success in clinical and translational science requires teamwork of individuals with complementary expertise. The TWD program proposes high-performance oriented, competency-based training and preparation to create a diverse, talented and committed workforce with the capacity to accelerate clinical translational science to improve the health of society. The TWD will provide education and training along a pipeline of programs beginning with students and trainees and extending to include career development for all faculty levels (instructor to professor) and staff (any person working on clinical or translational research). We will achieve these goals through the following Specific Aims: Aim 1: Develop and retain a highly qualified interdisciplinary team-focused workforce prepared to conduct rigorous clinical translational research (CTR). Aim 1.1. Ensure that the entire CTR workforce receives comprehensive training in Good Clinical Practice, Responsible Conduct of Research, research ethics, and regulatory compliance. Aim 1.2. Enhance the CCTSI’s Workforce effectiveness as teams by providing professional development initiatives in Team Science, Leadership and Mentorship. Aim 1.3. Develop, pilot and evaluate a Career Ladder for Professional Research Assistants to standardize professional development and competencies across their career trajectory. Aim 1.4. Close learning gaps identified by the CCTSI Workforce by offering new educational programs in big data/informatics, entrepreneurship, and dissemination and implementation sciences. The PTC Program will accelerate clinical and translational research through a strategic pilot grant program designed to provide funding for innovative ideas, research methods and collaborations by the CCTSI workforce. The Program will focus on the support of new research that will catalyze the translation of scientific discoveries into treatments, develop new approaches to advance translational science, promote community engagement in translational and team science and foster the development of young investigators in clinical and translational research. We will achieve these goals through the following Specific Aims: Aim 2: Implement a comprehensive Pilot Translational and Clinical Studies Program (PTC) to accelerate high quality collaborative CTR throughout the CCTSI partner affiliates. Aim 3: Conduct rigorous, transparent peer review of PTC applications to ensure that only projects with the greatest potential impact are supported by the program. Aim 4: Establish and implement metrics that will be used to monitor the impact of the PTC. The PTC will provide opportunities to address specific CCTSI priorities and open routes for innovative ideas and development of novel technologies. The Program will promote all disciplines of research and will prioritize research proposals that advance the science of translation. Program impact will be monitored both with NCATS Common Metrics and with metrics developed to meet the needs of the PTC locally.