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Biomedical Engineering Core

Biomedical Engineering Core
生物医学工程核心
批准号:
10635425
负责人:
Abraham Teunissen
金额:
$4.47万
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
未结题
起止时间:
2017-03-17 至 2028-07-31

项目摘要

项目成果

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中文摘要
翻译
核心C摘要 生物医学工程核心C将支持该计划项目的纳米研究。核心 将在纳米技术专家Abraham Teunissen博士的指导下在西奈山运作 和有机化学。Teunissen博士在领导科学家团队方面也拥有丰富的专业知识, 他担任西奈山放射化学设施主任和我们纳米医学实验室的联合主任。的 核心将提供训练有素的免疫抑制纳米生物制剂,用于调节应激诱导的免疫 在项目2和3中重新编程。核心将按需提供这些纳米治疗药物,并安排 他们的运输给所有的合作者。此外,Teunissen博士的专业知识使该核心能够有效地 通过开发新的纳米制剂来应对新发现的治疗靶点。
英文摘要
SUMMARY FOR CORE C The Biomedical Engineering Core C will support this program project's nanotherapeutic studies. The Core will operate from Mount Sinai under the direction of Dr. Abraham Teunissen, an expert in nanotechnology and organic chemistry. Dr. Teunissen also has extensive expertise in leading teams of scientists through his roles as Director of Mount Sinai’s Radiochemistry Facility and co-Director of our Nanomedicine lab. The Core will provide trained immunity-inhibiting nanobiologics for modulating stress-induced immune reprogramming in Projects 2 and 3. The Core will provide these nanotherapeutics on demand and arrange their transport to all collaborators. Moreover, Dr. Teunissen’s expertise enables this Core to efficiently respond to newly discovered therapeutic targets by developing novel nanoformulations.
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Studying and regulating trained immunity in mouse transplant models
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