Improving Family Cancer History Collection using Social Network, Human Centered Design, and Implementation Science Approaches

利用社交网络、以人为本的设计和实施科学方法改进家族癌症史收集

• 批准号: 10652994
• 负责人: Caitlin Gloeckner Allen
• 金额: $ 10.11万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10652994
• 关键词: Adult; African American; African American population; Award; Belief; Cancer Burden; Clinic; Clinical; Collection; Color; Communication; Communities; Community Clinical Oncology Program; Community Health; Complex; Continuity of Patient Care; Data Analyses; Death Rate; Development; Disparity; Early Diagnosis; Effectiveness of Interventions; Environment; Ethnic Population; Evaluation; Family; Family Cancer History; Family dynamics; Family health status; Family member; Fellowship; Genetic; Genetic Research; Genetic Risk; Goals; Health; Health Technology; Individual; Intervention; Interview; Knowledge; Learning; Link; Literature; Malignant Neoplasms; Maps; Medical; Mentors; Mentorship; Methodology; Methods; Minority Groups; NCI-Designated Cancer Center; Network-based; Outcome; Participant; Pathway Analysis; Patients; Personal Behavior; Phase; Positioning Attribute; Postdoctoral Fellow; Prevention strategy; Provider; Public Health Schools; Recording of previous events; Reporting; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Research Project Summaries; Resource-limited setting; Resources; Risk; Risk Reduction; Site; Social Network; Techniques; Technology Assessment; Training; Translating; Translational Research; Translations; Underrepresented Populations; Universities; Update; Work; Writing; academic preparation; cancer care; cancer genetics; cancer prevention; cancer risk; career; career development; clinical decision-making; design; effectiveness outcome; evidence base; family influence; follow-up; genetic information; human centered design; implementation outcomes; implementation research; implementation science; improved; innovation; marginalized population; member; novel; population health; pragmatic trial; primary care setting; programs; racial population; research and development; research data dissemination; risk stratification; screening; skills; systematic review; tool; training opportunity; underserved minority; uptake

PROJECT SUMMARY The research strategy and training plan included in this F99/K00 proposal will enhance the career development and research independence of Caitlin G. Allen, MPH. This research plan aims to advance knowledge of how to expand the reach and uptake of existing evidence-based genetics tools such as family cancer history (FCH) among underserved minority populations. FCH collection is a simple, proven way to identify individual's genetic risk for developing cancer that can encourage tailored cancer prevention and risk-stratified screening. Despite national efforts, FCH collection remains suboptimal with especially noteworthy disparities in collection among African American (AA) families. Ms. Allen's F99 research and training will focus on developing her skills in social network analysis to study individual and family network factors that contribute to poor knowledge of FCH. Ms. Allen has already completed two complementary dissertation studies that directly inform the proposed F99 research: 1) a systematic review of family health collection tools, and 2) development of a valid and reliable scale used to identify family network members that are highly likely to share FCH information. She will complete her dissertation research in the F99 phase of this award, which will involve: 1) 50 AA participants completing their FCH using a FCH collection tool (ItRunsInMyFamily), and 2) characterizing individual- and network-level factors that influence FCH collection by conducting personal network interviews using the Colored Eco-Genetic Relationship Map technique. To accomplish these aims, her F99 training objectives are to: 1) hone professional skills in grantsmanship, academic writing, and research dissemination, 2) develop scientific independence by strengthening methodological and analytic skills in social network analysis and relevant research methods, and 3) identify a postdoctoral site and K00 mentor. Ms. Allen's F99 training plan is bolstered by strong support from an excellent mentorship team at the Rollins School of Public Health and the research infrastructure at Emory University, creating an optimal training environment. Ms. Allen's postdoctoral research (K00 phase) will expand upon F99 work by enhancing a FCH collection tool (ItRunsInMyFamily) through human centered design approaches and implementing this tool in community-based clinical settings. Her training goals aligned with this phase of research includes: 1) building knowledge in human centered design and health technology assessment, 2) becoming an expert in implementation science, and 3) enhancing professional and research skills to prepare for an academic research position. Collectively, the integrated research plan and training goals are critical to establishing a successful, innovative, and meaningful academic career focused on extending cancer-specific genetics discoveries to marginalized and underrepresented populations by supporting evidence-based solutions such as FCH to improve cancer prevention and early-detection.

项目摘要 本F99/K 00提案中包含的研究策略和培训计划将促进职业发展 和研究的独立性。艾伦公共卫生硕士这项研究计划旨在促进了解如何 扩大现有循证遗传学工具的覆盖范围和使用，如家族癌症史（FCH） 在服务不足的少数群体中。FCH收集是一种简单，行之有效的方法来确定个人的遗传 这可以鼓励量身定制的癌症预防和风险分层筛查。尽管 在国家努力下，FCH收集仍然不是最佳的，特别值得注意的是， 非裔美国人（AA）艾伦女士的F99研究和培训将侧重于发展她的社交技能。 网络分析，研究个人和家庭网络因素，有助于FCH知识不足。女士 艾伦已经完成了两个互补的论文研究，直接通知拟议的F99 研究：1）对家庭健康收集工具进行系统审查，2）开发有效可靠的量表 用于识别很可能共享FCH信息的家庭网络成员。她会完成她的 该奖项的F99阶段的论文研究，将涉及：1）50名AA参与者完成他们的 使用FCH收集工具（ItRunsInMyFamily）的FCH，以及2）表征个体和网络级因素 通过使用有色生态遗传学进行个人网络访谈来影响FCH收集 关系图技术。为了实现这些目标，她的F99培训目标是：1）磨练专业 在语法，学术写作和研究传播的技能，2）发展科学的独立性， 加强社会网络分析和相关研究方法的方法和分析技能， 3)确定博士后站点和K 00导师。艾伦女士的F99培训计划得到了以下方面的大力支持： 罗林斯公共卫生学院的优秀导师团队和埃默里大学的研究基础设施 大学，创造最佳的培训环境。艾伦女士的博士后研究（K 00阶段）将扩大 通过以人为本的设计增强FCH收集工具（ItRunsInMyFamily）， 方法，并在社区为基础的临床环境中实施这一工具。她的训练目标与此一致 研究阶段包括：1）建立以人为本的设计和健康技术评估的知识， 2)成为实施科学方面的专家，以及3）提高专业和研究技能， 一个学术研究职位总的来说，综合研究计划和培训目标对以下方面至关重要： 建立一个成功的，创新的，有意义的学术生涯，专注于扩展癌症特异性 通过支持基于证据的解决方案，将遗传学发现提供给边缘化和代表性不足的人群 例如FCH，以改善癌症预防和早期检测。

项目成果

Basic behavioral science research priorities in minority health and health disparities.

• DOI: 10.1093/tbm/ibab143
• 发表时间: 2021-11-30
• 期刊: Translational behavioral medicine
• 影响因子: 3.6
• 作者: Halbert CH;Allen CG
• 通讯作者: Allen CG

Precision Public Health Initiatives in Cancer: Proceedings from the Transdisciplinary Conference for Future Leaders in Precision Public Health.

• DOI: 10.1186/s12919-022-00234-x
• 发表时间: 2022-07-07
• 期刊: BMC proceedings
• 作者: Allen, Caitlin G;Turbitt, Erin;Smit, Amelia K;Passero, Lauren E;Olstad, Dana Lee;Hatch, Ashley;Landry, Latrice;Roberts, Megan C
• 通讯作者: Roberts, Megan C

Hepatitis B Testing Among Vietnamese in Metropolitan Atlanta: The Role of Healthcare-Related and Acculturation-Related Factors.

• DOI: 10.1007/s10900-020-00947-0
• 发表时间: 2021-08
• 期刊: Journal of community health
• 影响因子: 5.9
• 作者: Vu M;Huynh VN;Berg CJ;Allen CG;Nguyen PH;Tran NA;Srivanjarean Y;Escoffery C
• 通讯作者: Escoffery C

Barriers and Facilitators for Population Genetic Screening in Healthy Populations: A Systematic Review.

• DOI: 10.3389/fgene.2022.865384
• 发表时间: 2022
• 期刊: Frontiers in genetics
• 影响因子: 3.7

Association between Neighborhood Social Deprivation and Stage at Diagnosis among Breast Cancer Patients in South Carolina.

• DOI: 10.3390/ijerph182211824
• 发表时间: 2021-11-11
• 期刊: International journal of environmental research and public health
• 作者: Babatunde OA;Zahnd WE;Eberth JM;Lawson AB;Adams SA;Boakye EA;Jefferson MS;Allen CG;Pearce JL;Li H;Halbert CH
• 通讯作者: Halbert CH