Comparative Biomedical Research Training for Veterinarians

兽医比较生物医学研究培训

• 批准号: 10645056
• 负责人: ALBERT MULENGA
• 金额: $ 22.72万
• 依托单位: TEXAS A&M AGRILIFE RESEARCH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-07 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10645056
• 关键词: Biomedical Research; Research Training; Veterinarians; comparative

Project Summary/Abstract The critical national shortage of veterinary scientists with PhD training who can provide their unique expertise in biomedical research recognized. The National Institutes of Health (NIH) and National Research Council have recognized that veterinarians are broadly trained health professionals who are uniquely qualified to lead biomedical research, having an understanding of disease in the context of the whole organism. The Texas A&M College of Veterinary Medicine (TAMU CVM) T32 training program is a three-year post-doctoral training program with the objective of providing PhD training to veterinarians in cutting edge biomedical research approaches and address the national need for this expertise. This renewal builds upon two previous successful project periods, 2010-2014 and 2015-2020, under the directorship of Dr. Ann Kier, who will assume an Advisor role to the PD (Albert Mulenga) and this renewal and serve on student committees. The TAMU CVM T32 will recruit outstanding trainees DVMS. In previous budget periods, trainees were recruited after they had completed their DVM residency program at the TAMU CVM or other schools in different specialties and had passed their specialty boards. During the residency program, prospective trainees with expressed desire to join the T32 program are advised to take relevant coursework pertinent to the PhD training. In this way, trainees will focus on conducting their dissertation research and complete PhD degree requirement within the three years that is supported under T32 funding. In the event that the trainee does not meet requirement for PhD graduation during the three-year T32 support, the mentor will provide support. During the two project periods, the program recruited 14 DVMs into graduate school. Of the 14 trainees, eight have graduated with their PhDs and seven have taken employment in biomedical research, one is in a temporary private practice, one is on schedule to complete her PhD, and five are still in training. Of the five; one trainee on track to finish in spring of 2020. Of the five, one trainee is on track to finish in spring of 2020 and the remaining are scheduled to graduate during this renewal: one trainee in year one of this renewal, and two in year two, and one in year 3. The NIH has recognized the fact that although the veterinary curriculum is analogous to medical school training, it provides an added benefit, the comparative nature of training in normal anatomy/physiology and abnormal disease states, providing an excellent basis for biomedical disease inquiry. This specialized training uniquely prepares veterinarian researchers to contribute to biomedical research in the modeling of human pathophysiology using laboratory animal models. The NIH Roadmap for Medical Research is designed to open up new opportunities to tackle the multifactorial causes of diseases not yet understood, particularly those associated with a longer lived, aging population, including heart disease, obesity, diabetes mellitus, autoimmunity, and increased susceptibility to infectious diseases. The comparative nature of their training equips veterinarians with insight and expertise to conduct clinical research.

项目摘要/摘要 兽医科学家和博士学位培训的兽医科学家的严重短缺，可以提供其独特的 认可生物医学研究的专业知识。美国国立卫生研究院（NIH）和国家研究 理事会已经认识到兽医是经过广泛培训的卫生专业人员，具有独特的资格 领导生物医学研究，在整个生物体的背景下了解疾病。这 德克萨斯州A＆M兽医学院（TAMU CVM）T32培训计划是一项三年的博士后 培训计划的目的是向较前沿生物医学研究提供博士学位培训 方法并满足国家对这种专业知识的需求。这种更新建立在两个以前的成功的基础上 根据Ann Kier博士的董事职位，2010- 2014年和2015 - 2020年项目期间，他将担任顾问 PD（Albert Mulenga）和此更新的角色，并在学生委员会任职。 Tamu CVM T32将 招募出色的学员DVM。在以前的预算期内，学员完成后招募了 他们在TAMU CVM或其他专业的其他学校的DVM居住计划，并通过了 专业委员会。在居住计划期间，有代表渴望加入T32的准学员 建议计划与博士培训有关的相关课程工作。这样，学员将专注于 在三年内进行论文研究和完整的博士学位要求 根据T32资金支持。如果受训者在期间不符合博士毕业的要求 三年的T32支持，导师将提供支持。在两个项目期间，该计划招募 14个DVM进入研究生院。在14名学员中，有8名已经获得了博士学位，七个毕业 在生物医学研究中的就业，一个正在临时私人执业中，一个人按计划完成她 博士学位和五个仍在培训中。五个；一名训练人正准备在2020年春季结束。在五个中，一个 受训者有望在2020年春季结束，其余的计划在此续签期间毕业： 该续约第一年的一名学员，第二年的两名学员，在第三年中有一名。 NIH认识到一个事实，尽管兽医课程类似于医学院 培训，它为正常解剖学/生理学和 异常疾病状态，为生物医学疾病查询提供了极好的基础。这个专门的培训 独特地准备兽医研究人员为人类建模的生物医学研究做出贡献 使用实验室动物模型的病理生理学。 NIH的医学研究路线图旨在开放 为解决尚不理解的疾病的多因素原因的新机会，尤其是那些 与较长的人口较长的人口相关，包括心脏病，肥胖，糖尿病，糖尿病， 自身免疫性，并增加了对传染病的敏感性。他们的培训的比较性质平等 具有洞察力和专业知识的兽医来进行临床研究。

项目成果

Retrospective Analysis of Aetiological Agents Associated with Pulmonary Mycosis Secondary to Enteric Salmonellosis in Six Horses by Panfungal Polymerase Chain Reaction.

• DOI: 10.1016/j.jcpa.2019.10.002
• 发表时间: 2020-01
• 期刊: Journal of comparative pathology
• 影响因子: 0.8
• 作者: Hensel M;Meason-Smith C;Plumlee QD;Myers AN;Coleman MC;Lawhon S;Rodrigues Hoffmann A;Rech RR
• 通讯作者: Rech RR

Granulomatous Rhinitis in a Horse due to Mycobacterium intracellulare Infection.

由于细胞内分枝杆菌感染而导致的马肉芽肿性鼻炎。

• DOI: 10.1016/j.jcpa.2019.04.001
• 发表时间: 2019
• 期刊: Journal of comparative pathology
• 影响因子: 0.8
• 作者: Vail,KJ;Stranahan,LW;Richardson,LM;Yanchik,AE;Arnold,CE;Porter,BF;Wiener,DJ
• 通讯作者: Wiener,DJ

A Salmonella Regulator Modulates Intestinal Colonization and Use of Phosphonoacetic Acid.

• DOI: 10.3389/fcimb.2017.00069
• 发表时间: 2017-01-01
• 期刊: Frontiers in cellular and infection microbiology
• 影响因子: 5.7
• 作者: Elfenbein, Johanna R;Knodler, Leigh A;Andrews-Polymenis, Helene L
• 通讯作者: Andrews-Polymenis, Helene L

Brucellosis in Dogs and Public Health Risk.

• DOI: 10.3201/eid2408.171171
• 发表时间: 2018-08
• 期刊: Emerging infectious diseases
• 影响因子: 11.8
• 作者: Hensel ME;Negron M;Arenas-Gamboa AM
• 通讯作者: Arenas-Gamboa AM

Mango polyphenolics reduce inflammation in intestinal colitis-involvement of the miR-126/PI3K/AKT/mTOR axis in vitro and in vivo.

• DOI: 10.1002/mc.22484
• 发表时间: 2017-01
• 期刊: MOLECULAR CARCINOGENESIS
• 影响因子: 4.6
• 作者: Kim, Hyemee;Banerjee, Nivedita;Barnes, Ryan C.;Pfent, Catherine M.;Talcott, Stephen T.;Dashwood, Roderick H.;Mertens-Talcott, Susanne U.
• 通讯作者: Mertens-Talcott, Susanne U.