Comprehensive Mechanisms in Reproductive Sciences

项目摘要和摘要 我们的计划目标是为研究密集型和与研究相关的职业培养有才华的年轻科学家 在生殖生物学方面。贝勒医学院是生殖生物学研究的长期领先者。 博士后和博士后学员接受生物医学研究和职业发展方面的指导培训 获得各种职业道路所需的技能。博士前项目结合了最先进的培训 在一流的生殖生物学实验室和授课学习中。博士后研究员参加课程和 除了他们的研究培训外，他们还参加了研讨会。这两家公司都将设立专门的研究和职业咨询委员会。 这包括一次正式的口头陈述。学员指导以特定于项目的个人发展为指导 计划(IDP)，与导师和一名核心执行委员会成员共同制定。活动至 加强教学、临床/翻译工作和创业方面的技能，由BCM和邻近的 世界上最大的医疗中心内的合作机构。计划特定活动包括受指导的 期刊俱乐部，一年一度的小型研讨会，研究咨询委员会，NRMN导师模块 培训、对口头交流的正式批评、协助发展研究金申请，以及 个人职业规划计划。这些方案还辅之以负责任的行为培训 研究和专门为这项提议设计的新的“生殖健康伦理学习单元”。这13个 教师被选为当代生殖生物学研究兴趣的对象，他们是 目前由超过1400万美元的资金支持，仅NICHD的资金就有600万美元(占PI总额的43% 资金)。他们的研究领域正好属于NICHD的任务范围，并包括关键生殖研究 雄性和雌性生殖组织的正常和病理生理学、遗传和 影响生育力的环境因素和翻译研究(男性避孕开发和 成人疾病的发育起源)。培训教师使用尖端方法来研究生殖 使用遗传模型、患者样本、体外模型和临床数据的过程。我们的计划是为 三名博士后学生和四名博士后研究员。我们计划为实习生提供两年的支持，并提供 参加第三年的比赛。由于BCM和AN的长期生殖生物学研究计划 积极的国家招聘战略，我们目前在我们的培训实验室有一个强大的申请者池，从中可以 选择学员，包括来自UR小组的博士后和博士后学员。总的来说，我们的计划提供了 为下一代科学家为成功和多样化的职业生涯做准备所需的技能和经验 在生殖生物学方面。

Project Summary and Abstract Our program goal is to train talented young scientists for research-intensive and research-related careers in reproductive biology. Baylor College of Medicine is a long-standing leader in reproductive biology research. Predoctoral and postdoctoral trainees receive mentored training in biomedical research and career development to obtain skills necessary for a variety of career paths. The predoctoral program combines state-of-the-art training in premier reproductive biology laboratories along with didactic learning. Postdoctoral fellows attend courses and seminars alongside their research training. Both will have structured committees for research and career advising that include a formal oral presentation. Trainee mentorship is guided by program-specific Individual Development Plans (IDP), developed in conjunction with the mentor and a core executive committee member. Activities to enhance skills in teaching, clinical/translational work, and entrepreneurship, is offered by BCM and neighboring collaborative institutions within the world's largest medical center. Program specific activities include a mentored journal club, an annual mini-symposium, research advisory committees, NRMN modules for mentor-mentee training, formal critiques of oral communications, assistance with development of fellowship applications, and individual career planning programs. These programs are supplemented with training in responsible conduct of research and a novel “ethics in reproductive health learning unit” specifically designed for this proposal. The 13 faculty members have been selected for contemporary research interests in reproductive biology and are currently supported by over $14 million in funding with $6 million in NICHD funding alone (43% of total PI funding). Their research areas fall squarely within the mission of NICHD, and includes studies of key reproductive biology proteins, normal and pathophysiology of male and female reproductive tissues, genetic and environmental factors that affect fertility, and translational research (male contraceptive development and developmental origins of adult disease). The training faculty use cutting edge approaches to study reproductive processes using genetic models, patient samples, in vitro models, and clinical data. Our program is designed for three predoctoral students and four postdoctoral fellows. We plan to support trainees for two years with an option to compete for a third year. Due to the long-standing reproductive biology research program at BCM and an active national recruiting strategy, we currently have a strong applicant pool in our training labs from which to select trainees, including pre- and postdoctoral trainees from UR groups. In total, our program provides necessary skills and experience to prepare the next generation of scientists for successful and diverse careers in reproductive biology.