DIVISION OF REPRODUCTIVE SCIENCES

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 生殖科学司从事与了解人类生殖以及控制生殖障碍和生育有关的生殖生物学方面的基础和应用研究。此外，作为俄勒冈健康与科学大学的一部分，该分部为进入以科学为导向的职业的个人(例如博士后和博士后研究员、妇女生殖健康研究[WRHR]学者计划的新教师，OB/GYN)提供培训，并为其他人(例如学校教师)提供研究经验。最后，该司是生殖研究的区域、国家和国际资源，尤其是与非人类灵长类有关的生殖研究。分部科学家(主管R.L.Stouffer博士)的研究侧重于了解中枢(神经)和外周(内分泌、旁分泌和自分泌)控制生殖功能的机制，主要是在女性中。研究项目涵盖了从配子(卵子和精子)发育开始，到后代的出生和哺育结束的整个生殖过程。在所有实验室中，一个明显的总主题是利用旧大陆猴子作为与人类生殖直接相关的整个动物、细胞和分子研究的模型。通过更好地了解基本的生殖过程，研究人员正在考虑生殖障碍的病因和潜在的治疗方法，以及避孕的新方法。此外，研究人员正在考虑通过辅助生殖技术，包括灵长类胚胎干细胞的研究和应用，为未来的生物医学研究建立独特的非人类模型。许多进展可以直接转化为女性健康、癌症、糖尿病、心血管研究、老龄化、肥胖症、神经科学和行为方面的问题。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Division of Reproductive Sciences conducts basic and applied research on aspects of reproductive biology relevant to understanding human reproduction and to controlling reproductive disorders and fertility. In addition, the division, as part of the Oregon Health & Science University, provides training for individuals entering science-oriented careers (e.g., pre- and postdoctoral fellows, new faculty in the Women's Reproductive Health Research [WRHR] scholar program, OB/GYN) and research experience for others (e.g., school teachers). Finally, the division serves as a regional, national and international resource for reproductive research, especially as it relates to nonhuman primates. The research of Division scientists (Dr. R.L. Stouffer, Head) focuses on understanding the central (neural) and peripheral (endocrine, paracrine, and autocrine) mechanisms controlling reproductive function, primarily in females. Research projects span the continuum of reproduction that begins with gamete (egg and sperm) development and ends with the birth and nursing of an offspring. A general theme apparent in all laboratories is the utilization of Old World monkeys as a model for whole animal, cellular and molecular studies of direct relevance to human reproduction. Through a better understanding of basic reproductive processes, investigators are considering the etiology and potential treatment of reproductive disorders, as well as novel approaches for contraception. Also, researchers are considering unique nonhuman models for future biomedical research through assisted reproductive technologies, including the study and application of primate embryonic stem cells. Many advances can be directly translated to issues in women's health, cancer, diabetes, cardiovascular research, aging, obesity, neuroscience and behavior.