Multidisciplinary Training in Ethnic Diversity and Cancer Disparities

健康差距的根源在于生物、社会、文化、行为和经济方面的多样性。 个人和群体的特征。对种族/民族差异的研究始于 了解各组的特征以及这些特征如何影响癌症的发展 和结果。这个新的申请联合T32博士后培训计划在夏威夷大学 癌症中心（UHCC）和南加州大学（USC）诺里斯综合癌症中心 （NCCC）利用独特的资源，多种族队列（MEC）研究， 一项基于人群的前瞻性队列研究，跟踪了非裔美国人、夏威夷土著人、日本人、 在过去的25年里，美国人，拉丁美洲人和白人。与癌症登记、医疗保险和其他数据的联系 来源为MEC和许多其他癌症差异研究提供了各种终点， 机构职能体系UHCC和南加州大学的互补研究得到了前沿核心和利益的支持 从多年的经验。拟议培训方案的具体目标是： 1.培养博士后研究员在不同人群中从事癌症研究的独立职业， 特别关注导致癌症健康的社会文化、营养、生活方式和生物风险因素 各种少数民族/种族之间的不平等。该计划是非常独特的，将利用长期- 两个NCI指定的癌症中心的研究项目之间的长期（30年以上）合作， 在流行病学研究的培训和工具方面有更广泛的经验。 2.在多学科环境中提供广泛的应用研究经验，重点是营养， 分子，遗传和转化流行病学，建立在多个独特的种族和民族 癌症的各种研究。加上强大的指导，这些研究将作为核心， 有效的跨学科培训，使受训者能够设计创新的高影响力项目， 并将为癌症健康差异研究的职业生涯做好准备。 在5年的资助期内，该培训项目将在夏威夷和洛杉矶分别培养8名和10名博士后研究员 洛杉矶。所有学员将接触到广泛的创新分子和传统的癌症预防 方法（流行病学，生物标志物，基因组学和营养），以解决广泛的癌症差异 通过密切合作，在夏威夷和加州的民族/种族人口的研究问题 在两个地点设立导师和定期互访。定期进行的两地培训包括： 交流访问，是拟议的培训计划的一个特别优势，因为它将提供接触多个， 机构和多学科的合作研究，建立在专业知识和长期的 UH和USC在研究，教育和培训方面的合作。

At the root of health disparities is the diversity in the biological, social, cultural, behavioral, and economic characteristics of individuals and populations. The study of ethnic/racial disparities begins with an understanding of the characteristics of each group and how these characteristics affect cancer development and outcomes. This new application for a joint T32 postdoctoral training program at University of Hawaii Cancer Center (UHCC) and the University of Southern California (USC) Norris Comprehensive Cancer Center (NCCC) addresses cancer health disparities utilizing a unique resource, the Multiethnic Cohort (MEC) Study, a population-based prospective cohort study that has followed African Americans, Native Hawaiians, Japanese Americans, Latinos, and whites for the past 25 years. Linkages to cancer registries, Medicare, and other data sources provide a variety of endpoints for MEC and many other cancer disparity studies conducted at both institutions. The complementary research at UHCC and USC is supported by cutting edge cores and benefits from many years of experience. The specific aims of the proposed training program are: 1. To train postdoctoral fellows for independent careers in cancer research in diverse populations, with a specific focus on the sociocultural, nutritional, lifestyle and biological risk factors leading to cancer health disparities in a variety of ethnic/racial minorities. This program is highly unique and will leverage the long- standing (30+ years) collaboration between research programs at two NCI-designated Cancer Centers to permit a broader experience in training and tools for epidemiological research. 2. To provide extensive applied research experience in a multidisciplinary environment focusing on nutritional, molecular, genetic and translational epidemiology that builds on multiple unique racial and ethnically diverse studies of cancer. Together with strong mentorship, these studies will serve as the centerpiece for an effective transdisciplinary training, which will allow trainees to design innovative high-impact projects, and will prepare trainees for careers in cancer health disparities research. During the 5-year grant period, the training program will educate 8 postdoctoral fellows in Hawaii and 10 in Los Angeles. All trainees will be exposed to a wide range of innovative molecular and traditional cancer prevention approaches (epidemiology, biomarkers, genomics, and nutrition) to address a wide range of cancer disparity research questions across the ethnic/racial populations in Hawaii and California through the close cooperation of mentors in both locations and regular exchange visits. The dual-site training, which regular includes exchange visits, is a particular strength of the proposed training program as it will provide exposure to multi- institutional and multi-disciplinary collaborative research that builds on the expertise and long-standing collaboration between UH and USC in research, education and training.