NRSA Training Core

NRSA 培训核心

• 批准号: 10654042
• 负责人: Emma Anne Meagher
• 金额: $ 31.49万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10654042
• 关键词: Appointment; Awareness; Biography; Caliber; Career Choice; Categories; Cities; Clinical; Code; Competence; Country; County; Coupled; Credentialing; Data Science; Dedications; Development; Discipline; Doctor of Philosophy; Education; Educational Curriculum; Educational workshop; Electronic Mail; First Name; Funding; Funding Opportunities; Grant; Health Priorities; Healthcare; Industry; K-Series Research Career Programs; Knowledge; Last Name; Lead; Master of Science; Mentors; Mission; Names; National Research Service Awards; Patient Care; Peer Review; Pennsylvania; Persons; Pharmacy facility; Positioning Attribute; Postdoctoral Fellow; Principal Investigator; Province; Publications; Research; Research Personnel; Review Literature; Role; Science; Scientist; Solid; Specific qualifier value; TNFSF15 gene; Telefacsimile; Telephone; Time; Training; Training Programs; Translating; Translational Research; Translations; United States; Universities; biomedical informatics; career; clinical care; clinical training; clinical translation; cohort; design; diversity and inclusion; expectation; expiration; flexibility; implementation science; improved; innovation; medical schools; next generation; pre-doctoral; programs; recruit; skills; skills training; training opportunity; translational therapeutics

Contact PD/PI: FITZGERALD, GARRET A NRSA-Training-001 (532) TL1 Abstract: NRSA Training Core The purpose of the Penn NRSA Training Core is to enhance training in clinical translational science (CTS) to expedite the translation of scientific discovery into therapy and improve the quality of patient care. The mission of our TL1 program is to (i) recruit and train a next generation of CTS investigators who are equipped with the awareness, knowledge and skills necessary to successfully translate discoveries into clinical care, and (ii) to prepare them for a range of research careers. Penn’s TL1 program is designed to attract, train and support a diverse cohort of predoctoral trainees from graduate research programs (PhD, MD/PhD, VMD/PhD) and clinical training programs (MD, VMD, DMD) as well as postdoctoral research scientists (PhD) and clinicians (MD, VMD, DMD). Appointees enter their CTS training from various educational trajectories and with diverse expectations and career aspirations; for this reason the Penn TL1 is flexible and inclusive of cross-disciplinary coursework and/or completion of a graduate-level certificate or Master’s degree. Appointment durations vary between one year for predoctoral appointees and either one or 2-3 years for postdoctoral appointees. Predoctoral trainees will complete the TL1 with a solid understanding of the discipline and core competencies for performing CTS research. Postdoctoral trainees will have demonstrated CTS research independence in the form of publication in peer-reviewed literature, appointment to a mentored career development award or other independent grant funding and an academic or industry appointment with continued substantial engagement in CTS. Coupled with a dedicated mentoring program and a robust diversity and inclusion effort, the objectives of the TL1 program are based on the following: 1. (i) Continue to provide a comprehensive curriculum in discovery-, entrepreneurial-, and regulatory science, translational therapeutics, and biomedical informatics; (ii) expand coursework to include data- and implementation science, investigational pharmacy, and health care innovation; and (iii) continue to increase the awareness of CTS training opportunities to recruit high caliber trainees. 2. (i) Continue development efforts on professional skills training, and (ii) add programs to support postdoctoral trainees at points of transition and prepare postdoctoral PhDs for diverse career paths. 3. Develop skills-based workshops and labs for all TL1 trainees that are responsive to real-time innovations in science, shifting health priorities and rapidly evolving learner needs. 4. Expand opportunities for pre- and postdoctoral trainees to immerse themselves in projects at the academic- industry interface through the creation of shared training programs so that they may partake in real-world scenarios of innovation being reduced to practice. Project Summary/Abstract Page 1246 Contact PD/PI: FITZGERALD, GARRET A NRSA-Training-001 (532) OMB Number: 4040-0010 Expiration Date: 12/31/2022 RESEARCH & RELATED Senior/Key Person Profile (Expanded) PROFILE - Project Director/Principal Investigator Prefix: First Name*: Emma Middle Name Anne Last Name*: Meagher Suffix: Position/Title*: Senior Associate Dean for Clinical Res Organization Name*: University of Pennsylvania Department: Division: Street1*: ITMAT - Perelman School of Medicine Street2: 3400 Spruce Street City*: PHILADELPHIA County: State*: PA: Pennsylvania Province: Country*: USA: UNITED STATES Zip / Postal Code*: 191040000 Phone Number*: 215-662-2174 Fax Number: E-Mail*: [e-mail] Credential, e.g., agency login: emeagher Project Role*: Other (Specify) Other Project Role Category: Project Lead Degree Type: MD Degree Year: 1987 Attach Biographical Sketch*: File Name: Attach Current & Pending Support: File Name: Page 1247 Tracking Number: GRANT13073932 Funding Opportunity Number: PAR-18-940 . Received Date: 2020-04-16T15:07:17.000-04:00

联系PD/PI：FITZGERALD，GARRET A NRSA-Training-001（532） TL 1摘要：NRSA培训核心 Penn NRSA培训核心的目的是加强临床转化科学（CTS）的培训， 加快将科学发现转化为治疗方法，提高病人护理质量。使命 我们的TL 1计划的目的是（i）招募和培训下一代CTS调查员，他们配备了 成功地将发现转化为临床护理所需的意识、知识和技能，以及（ii） 为他们的研究生涯做好准备。宾夕法尼亚大学的TL 1计划旨在吸引，培训和支持 来自研究生研究项目（博士，医学博士/博士，VMD/博士）和临床的博士前学员的多样化队列 培训计划（MD，VMD，DMD）以及博士后研究科学家（PhD）和临床医生（MD，VMD， DMD）。被任命者从不同的教育轨迹和不同的期望进入他们的CTS培训 和职业抱负;因此，宾夕法尼亚大学TL 1是灵活的，包括跨学科的课程 和/或完成研究生水平证书或硕士学位。任命期限在一个 博士前受聘者为1年，博士后受聘者为1年或2-3年。博士前实习生将 在充分理解执行CTS的规程和核心能力的情况下完成TL 1 research.博士后学员将以出版物的形式证明CTS研究的独立性 在同行评审的文献中，任命为指导职业发展奖或其他独立补助金 资金和学术或行业任命，并继续大量参与CTS。加上 一个专门的指导计划和一个强大的多样性和包容性的努力，TL 1计划的目标是 基于以下方面： 1. (i)继续提供发现，创业和监管科学的综合课程， 转化治疗学和生物医学信息学;（ii）扩大课程，包括数据-和 实施科学，研究药学和医疗保健创新;（iii）继续增加 了解CTS培训机会，招募高素质的学员。 2. (i)继续发展专业技能培训，以及（ii）增加支持博士后的项目 在过渡点培训学员，并准备博士后博士学位的不同职业道路。 3.为所有TL 1学员开发基于技能的研讨会和实验室，以响应实时创新， 科学，不断变化的健康优先事项和快速变化的学习者需求。 4.为博士前和博士后学员扩大机会，让他们沉浸在学术领域的项目中- 通过创建共享的培训计划，使他们可以参与现实世界的行业界面 将创新转化为实践。 项目摘要/摘要第1246页 联系PD/PI：FITZGERALD，GARRET A NRSA-Training-001（532） OMB编号：4040-0010 发布日期：12/31/2022 研究及相关高级/关键人员简介（扩展） 项目负责人/主要研究者 前缀：名字 *：Emma中间名Anne姓氏 *：Meagher后缀： 职位/头衔 *：临床研究高级副院长 学校名称：University of Pennsylvania 所属部门： 部门： Street 1 *：ITMAT -佩雷尔曼医学院 街道2：3400 Spruce Street 城市 *：PHILADELPHIA 县： 州名 *：PA：Pennsylvania 省份： 国家 *：美国：美国 邮编 *：191040000 电话号码 *：215-662-2174传真号码： E-Mail*：[e-mail] 凭证，例如，机构登录：emeagher 项目角色 *：其他（指定）其他项目角色类别：项目负责人 学位类型：MD学位年份：1987年 附上简历 *：文件名： 附加当前支持（& Pending Support）：文件名： 第1247页 跟踪编号：GRANT 13073932资助机会编号：PAR-18-940。接收日期： 2020-04-16T15：07：17.000-04：00

项目成果

Solitary chemosensory cells producing interleukin-25 and group-2 innate lymphoid cells are enriched in chronic rhinosinusitis with nasal polyps.

• DOI: 10.1002/alr.22142
• 发表时间: 2018-05-09
• 期刊: International forum of allergy & rhinology
• 影响因子: 6.4
• 作者: Patel NN;Kohanski MA;Maina IW;Triantafillou V;Workman AD;Tong CCL;Kuan EC;Bosso JV;Adappa ND;Palmer JN;Herbert DR;Cohen NA
• 通讯作者: Cohen NA

Multisystem Inflammatory Syndrome in Children: Examining Emerging Data and Identifying Key Knowledge Gaps.

• DOI: 10.1097/pec.0000000000002633
• 发表时间: 2022-02-01
• 期刊: Pediatric emergency care
• 影响因子: 1.4
• 作者: Sartori LF;Balamuth F
• 通讯作者: Balamuth F

Congenital polyvalvular disease expands the cardiac phenotype of the RASopathies.

• DOI: 10.1002/ajmg.a.62146
• 发表时间: 2021-05
• 期刊: American journal of medical genetics. Part A
• 作者: Matalon DR;Stevenson DA;Bhoj EJ;Santani AB;Keena B;Cohen MS;Lin AE;Sheppard SE;Zackai EH
• 通讯作者: Zackai EH

Cultivating Interest in Heart Failure Careers: Can We Reverse the Current Trend?: Cultivating Interest in Heart Failure Careers.

• DOI: 10.1016/j.cardfail.2021.04.009
• 发表时间: 2021-07
• 期刊: Journal of cardiac failure
• 影响因子: 6
• 作者: Chuzi S;Reza N
• 通讯作者: Reza N

Astrocyte ethanol exposure reveals persistent and defined calcium response subtypes and associated gene signatures.

• DOI: 10.1016/j.jbc.2022.102147
• 发表时间: 2022-08
• 期刊: JOURNAL OF BIOLOGICAL CHEMISTRY
• 影响因子: 4.8
• 作者: Kim, Hyun-Bum;Lu, Youtao;Oh, Seonkyung C.;Morris, Jacqueline;Miyashiro, Kevin;Kim, Junhyong;Eberwine, James;Sul, Jai-Yoon
• 通讯作者: Sul, Jai-Yoon