Child/Adolescent/Young Adult HIV Research Training

儿童/青少年/青年艾滋病毒研究培训

• 批准号: 10698265
• 负责人: LARRY K BROWN
• 金额: $ 44.4万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10698265
• 关键词: Adolescent; Child; HIV; Research Training; young adult

ABSTRACT In the next decade, well trained researchers are needed to address the challenge of HIV/AIDS especially among children, adolescents, and young adults. Effective intervention programs are needed for both the prevention and treatment of HIV. This research training program will prepare Ph.D. and M.D. fellows to carry out independent research. Our faculty in the Division of Child and Adolescent Psychiatry have expertise in HIV prevention and treatment, adolescent risk behaviors, normative development, psychopathology, and the psychology of physically ill youth. Additional faculty at Brown (through the Center for AIDS Research, Division of Infectious Disease, and School of Public Health) have expertise in the medical care of HIV infected youth and adults, HIV testing, treatment as prevention, Pre-Exposure Prophylaxis, sexually transmitted infections, substance abuse, and international health. The strong faculty record of NIH funded research ensures that trainees are exposed to thriving areas of programmatic research. Training involves interdisciplinary and translational elements to prepare trainees for the integration of the medical, psychiatric, and developmental issues and as they inform biobehavioral HIV/AIDS research. The program has a total of six postdoctoral trainees and one summer trainee each year. Two or three new psychology trainees are enrolled every year for a two-year fellowship (with an optional third year) and one new M.D. is enrolled in alternate training years. Consistent with each trainee’s individual needs, a graduated program for progressive independent research is designed. A formal training curriculum targets specific learning objectives to develop the skills needed for the next generation of HIV research. Core areas of learning include models of behavior and its change; the influence of heath disparities on HIV risk, infection, and treatment; the adaptation of evidence-based interventions and implementation science; the biology of HIV, its prevention and its treatment; and advanced statistical techniques such as comparative effectiveness, cost-effectiveness, and transmission network analyses. Curriculum needs are satisfied by HIV-specific seminars, general research design seminars, and tutorials in addition to formal courses at Brown or nearby universities. The postdoctoral graduates from our three cycles have been very successful - 19 of the 32 postdoctoral graduates (60%) have become PIs on NIH K or R series grants and the rate is similar in the current cycle (56%) and prior (61%). In addition, they have authored 260 relevant peer-reviewed publications related to their training, 102 of which were authored by graduates of this cycle. These outcomes suggest that our training program is meeting its goal of preparing trainees to conduct high quality, relevant, HIV research.

摘要 在未来十年，需要训练有素的研究人员来应对艾滋病毒/艾滋病的挑战， 在儿童、青少年和年轻人中。有效的干预方案是必要的， 预防和治疗艾滋病毒。这个研究培训计划将准备博士学位。和医学博士。伙计们抬着 独立研究。我们的教师在儿童和青少年精神病学司有艾滋病毒的专业知识 预防和治疗，青少年危险行为，规范发展，精神病理学， 身体不适的年轻人的心理。布朗大学的其他教师（通过艾滋病研究中心， 传染病学院和公共卫生学院）在艾滋病毒感染青年的医疗护理方面具有专门知识 艾滋病毒检测，预防治疗，暴露前预防，性传播感染， 药物滥用和国际卫生。美国国立卫生研究院资助的研究的强大教师记录确保， 受训人员接触到蓬勃发展的方案研究领域。培训涉及跨学科和 翻译元素，为学员准备整合医疗，精神病学，和发展 问题，并为生物行为艾滋病毒/艾滋病研究提供信息。该计划共有6名博士后 每年有一名实习生和一名暑期实习生。每年招收两三名新的心理学实习生， 一个为期两年的奖学金（可选第三年）和一个新的医学博士。在不同的培训年注册。 与每个学员的个人需求相一致，渐进式独立研究的毕业课程是 设计了正式的培训课程针对具体的学习目标， 下一代艾滋病研究学习的核心领域包括行为模式及其变化; 健康差异对艾滋病毒风险、感染和治疗的影响; 干预和实施科学;艾滋病毒的生物学，其预防和治疗;以及先进的 统计技术，如比较有效性，成本效益和传输网络 分析。课程需要通过专门针对艾滋病毒的研讨会、一般研究设计研讨会和 除了布朗大学或附近大学的正式课程外，还可以参加辅导课程。我们的博士后毕业生 三个周期非常成功-32名博士后毕业生中有19名（60%）成为NIH的PI K或R系列赠款，本周期（56%）和上一周期（61%）的比率相似。此外，他们还 撰写了260篇与培训相关的同行评审出版物，其中102篇由 这个周期的毕业生。这些结果表明，我们的培训计划正在实现其目标， 接受培训的人员进行高质量的、相关的艾滋病毒研究。

项目成果

Blood Donation, Sexual Practices, and Self-Perceived Risk for HIV in the United States Among Young Adult Men Who Have Sex With Men.

美国男男性行为青年男性的献血、性行为和自我感知的艾滋病毒风险。

• DOI: 10.1177/0033354918815182
• 发表时间: 2019
• 期刊: Public health reports (Washington, D.C. : 1974)
• 作者: Wentz,AnnaE;Merchant,RolandC;Clark,MelissaA;Liu,Tao;Rosenberger,JoshuaG;Bauermeister,JoséA;Mayer,KennethH
• 通讯作者: Mayer,KennethH

Nesting Environment Provides Sex-Specific Neuroprotection in a Rat Model of Neonatal Hypoxic-Ischemic Injury.

筑巢环境在新生儿缺氧缺血性损伤大鼠模型中提供性别特异性神经保护。

• DOI: 10.3389/fnbeh.2018.00221
• 发表时间: 2018
• 期刊: Frontiers in behavioral neuroscience
• 影响因子: 3
• 作者: Mason,Briana;Rollins,LG;Asumadu,Evans;Cange,Christina;Walton,Najah;Donaldson,STiffany
• 通讯作者: Donaldson,STiffany

Youth Who Have Lived in Alternative Care in Nigeria, Zambia, and Zimbabwe: Mental Health and Violence Outcomes in Nationally Representative Data.

尼日利亚、赞比亚和津巴布韦生活在替代性照料环境中的青年：国家代表性数据中的心理健康和暴力结果。

• DOI: 10.1016/j.jaacop.2023.05.002
• 发表时间: 2023
• 期刊: JAACAP open
• 作者: Neville,SarahElizabeth;Okunoren,Oladoyin;Crea,ThomasM
• 通讯作者: Crea,ThomasM

Alcohol Use Predicts Sexual Decision-Making: A Systematic Review and Meta-Analysis of the Experimental Literature.

• DOI: 10.1007/s10461-015-1108-9
• 发表时间: 2016-01
• 期刊: AIDS and behavior
• 影响因子: 4.4
• 作者: Scott-Sheldon LA;Carey KB;Cunningham K;Johnson BT;Carey MP;MASH Research Team
• 通讯作者: MASH Research Team

The Daily Relationship Between Aspects of Food Insecurity and Medication Adherence Among People Living with HIV with Recent Experiences of Hunger.

• DOI: 10.1007/s12160-016-9812-x
• 发表时间: 2016-12
• 期刊: Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
• 作者: Pellowski JA;Kalichman SC;Cherry S;Conway-Washington C;Cherry C;Grebler T;Krug L
• 通讯作者: Krug L