New England Center of Excellence in Vector-Borne Diseases

在新英格兰，主要的媒介传播疾病(VBD)负担是由于扁虱、扁虱控制和 压制做法几乎跟不上地区特有的情况，尽管新英格兰 扁虱有着悠久的历史。新英格兰仅占美国人口的4.5%，占确认人口的20% 美国莱姆病病例。该项目建议建立一个媒介传播的新英格兰卓越中心 疾病(NEWVEC)在防治壁虱和其他节肢动物病媒方面取得重大进展 新英格兰六州通过应用研究和技术评估方法预防病媒 防止蚊虫叮咬，抑制致病媒介，并促进公众采取媒介控制措施。维持 并放大这一公共卫生需求，NEWVEC将培训学生进入公共卫生昆虫学 员工解决VBD问题，并将通过实践社区与利益相关者接触，以帮助其 研究和培训努力仍然是相关的、有效的和有影响力的。NEWVEC战略有三个方面 内容：扁虱抑制的应用研究，培训具有以下专业知识的公共卫生昆虫学家 病媒传播疾病和实践共同体，以提高循证医学的区域效力 方法：研究方法。应用研究项目将遵循四个平行的流程：1)规范和优化个人 商业和住宅用保护和控制产品及应用；2)发现和 评估抑制扁虱和防止扁虱叮咬的新兴技术；3)设计和测试栖息地 以宿主为目标的干预措施，以抑制蜱类种群；以及4)评估人为因素和公共卫生 防治扁虱的方法。这些领域的工作将由新英格兰六所大学的研究人员进行 大学，由两个核心设施支持：用于病原体检测的分子分析实验室和分类学吧- 在马萨诸塞大学阿默斯特分校(UMA)进行编码，并在 罗德岛大学。以UMA为基础的公共卫生昆虫学多层次培训计划将 在本科生和研究生水平上发展集中和证书计划，以进行高质量的培训 胜任毕业生在该领域就业，同时提供一系列高素质的专业人才 商业银行公共卫生专业人员和技术人员发展培训经验 新英格兰各地的应用公司。NEWVEC的实践社区将促进学术外 在研究中进行合作，促进中心研究人员之间重要知识的双向传播， 它的学生和受训人员、公共卫生利益相关者社区以及其他关注媒介传播的人 新英格兰的疾病预防。NEWVEC将专注于最重要的新英格兰媒介， VBD进展的最具挑战性的障碍，以及最有希望和最有效的媒介控制干预措施和 方法：研究方法。由于在技术上是可信的，NEWVEC将受到VBD实践社区的依赖，因此 影响建议的采纳并促进可伸缩性，以覆盖新英格兰地区的所有地区。

In New England, where the predominant vector-borne disease (VBD) burden is due to ticks, tick control and suppression practices can barely keep up with regional endemicity conditions, despite the fact that New England has a long history with ticks. With just 4.5% of the U.S. population, New England accounts for 20% of confirmed Lyme disease cases in the U.S. This project proposes a New England Center of Excellence in Vector-Borne Diseases (NEWVEC) to make significant progress in combatting ticks and other arthropod disease vectors in the six New England states through applied research and technical evaluation of methods to prevent vector bites, suppress disease-causing vectors, and promote public adoption of vector-control measures. To sustain and amplify this public health imperative, NEWVEC will train students to enter the public health entomology workforce to address VBD, and will engage stakeholders through a community of practice that can help its research and training efforts remain relevant, effective, and impactful. The NEWVEC strategy has three components: Applied research on tick suppression, Training of public health entomologists with expertise in vector-borne diseases, and Community of Practice to enhance regional effectiveness of evidence-based methods. Applied research projects will follow four parallel streams: 1) Standardizing and optimizing personal protection and control products and applications for commercial and residential use; 2) Discovering and evaluating emerging technologies to suppress ticks and prevent tick biting; 3) Designing and testing habitat and host-targeted interventions for suppressing tick populations; and 4) Assessing human factors and public health approaches for tick control. Work in these areas will be conducted by researchers at six New England universities, supported by two core facilities: a Molecular Analysis lab for pathogen testing and taxonomic bar- coding at the University of Massachusetts Amherst (UMA), and a Tick rearing and experimental test bed at the University of Rhode Island. A multi-tiered training program in Public Health Entomology based at UMA will develop concentrations and certificate programs at both the undergraduate and graduate levels to train highly competent graduates for employment in the field, while providing a range of high-quality professional development training experiences for public health professional staff and technical employees of commercial applicator firms around New England. NEWVEC’s Community of Practice will promote extra-academic collaboration in its research, promoting two-way transmission of vital knowledge among the center’s researchers, its students and trainees, the public health stakeholder community, and others concerned with vector-borne disease prevention in New England. NEWVEC will concentrate on the most important New England vectors, most challenging barriers to VBD progress, and most promising and impactful vector control interventions and methods. By being technically credible, NEWVEC will be relied upon by the VBD practice community, thus influencing adoption of recommendations and promoting scalability to reach all areas in the New England region.