Multi-sector, multi-level interventions for improving cancer prevention and control addressing persistent poverty

多部门、多层次的干预措施，改善癌症预防和控制，解决持续贫困问题

• 批准号: 10661437
• 负责人: Alexandra K. Adams
• 金额: $ 196.9万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-03 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661437
• 关键词: Address; Adoption; Advanced Malignant Neoplasm; American Indians; Area; Belief; Cancer Burden; Cancer Center; Cancer Control; Cancer Control Research; Cancer Prevention Intervention; Carcinogens; Censuses; Collaborations; Communities; Dissemination and Implementation; Eligibility Determination; Equity; Fostering; Funding; Goals; Health; Healthcare Systems; Individual; Infrastructure; Institution; Intervention; Latino; Leadership; Longevity; Malignant Neoplasms; Mentors; Methods; Montana; National Cancer Institute; Neighborhood Health Center; Oregon; Outcome; Pilot Projects; Policies; Population; Poverty; Poverty Areas; Prevention Research; Prevention program; Primary Care; Public Health; Recording of previous events; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Rural; Rural health equity; Scientist; Services; South Dakota; Structure; System; Tobacco Use Cessation; Tobacco use; Training Activity; Training Programs; Universities; Utah; Wisconsin; Work; cancer prevention; career; community engagement; community organizations; community partnership; diabetes prevention program; evidence base; experience; frontier; health equity; health goals; health inequalities; implementation research; implementation strategy; improved; innovation; low socioeconomic status; obesity prevention; patient oriented; programs; quitline; social health determinants; synergism; tobacco cessation intervention; translational research program; tribal community

OVERALL: PROJECT SUMMARY The overall, long-term goal of “HOPE & CAIRHE 2gether (HC2)” is to increase the reach of evidence-based cancer prevention and control interventions (EBIs) in areas of persistent poverty (PP). HC2 brings together the expertise, infrastructure, partnerships, and resources of the Center for Health Outcomes and Population Equity (HOPE), Huntsman Cancer Institute, and University of Utah, with the Center for American Indian and Rural Health Equity (CAIRHE) and Montana State University. HC2’s community level, translational research programs align with communities’ cultural beliefs, resources, and priorities; reach across the lifespan; and, strategically partner with key “anchor organizations,” public health agencies, healthcare systems, American Indian communities, and community organizations across five states. The HC2 Network brings together the robust community partnerships across institutions to create a unique resource for advancing cancer prevention in PP areas in the Mountain West, and HC2 is guided by a Community and Scientific Advisory Board. Projects 1 and 2 address the major drivers of the disproportionate burden of cancer among PP areas and populations. Project 1 partners with Community Health Centers (CHCs) to address tobacco cessation and mitigate the negative impacts of the social determinants of health (SDOH) among CHC patients in Utah who use tobacco and live in PP census tracts (majority Latino). Project 2 partners with Cooperative Extension Systems (CES) to address obesity prevention and SDOH among American Indian communities located in PP census tracts in Montana, Oregon, South Dakota, and Wisconsin (all census tracts are rural/frontier). Both Projects include Project Steering Committees and Project 2 includes Local Community Advisory Boards in each community. An overarching theme creating synergy across HC2 activities and research is increasing “Reach through Equitable Implementation.” As such, HC2 implementation strategies are specifically tailored to local and community contexts. HC2’s structure and function creates substantial synergy to advance cancer prevention research in areas and populations experiencing persistent poverty via: Complementary areas of expertise, experience, community engagement, and leadership across institutions; Innovative, comprehensive, multi- level, conceptual framework targeting Reach through Equitable Implementation, with shared research foci that drive the research programs; Multi-faceted, cross-institutional training program that leverages the complementary strengths and access to trainee populations across Utah and Montana; and, Combining deep and extensive community engagement and robust partnerships across institutions to create the HC2 Network, which will help bridge the gap between scientific discovery and the implementation of EBIs in areas of PP. In sum, HC2 will build on existing expertise, research infrastructures, and longstanding partnerships to serve as a regional and national leader in community-engaged cancer prevention and control research in areas of PP.

总体：项目摘要 “HOPE & CAIRHE 2gether（HC 2）”的总体长期目标是增加循证医学的覆盖面， 在持续贫困地区采取癌症预防和控制干预措施。HC 2汇集了 卫生成果和人口公平中心的专业知识、基础设施、伙伴关系和资源 （HOPE），亨茨曼癌症研究所，犹他州大学，美国印第安人和农村中心 健康公平（CAIRHE）和蒙大拿州立大学。HC 2的社区水平，转化研究 计划与社区的文化信仰、资源和优先事项保持一致;覆盖整个生命周期; 与主要“锚组织”、公共卫生机构、医疗保健系统、美国 印第安人社区和五个州的社区组织。HC 2网络汇集了 跨机构建立强大的社区伙伴关系，为推进癌症预防创造独特的资源 在西部山区的PP地区，HC 2由社区和科学咨询委员会指导。项目 1和2解决了PP地区和人群中癌症负担不成比例的主要驱动因素。 项目1与社区卫生中心（CHC）合作，解决戒烟问题， 犹他州吸烟的CHC患者中健康的社会决定因素（SDOH）的负面影响 生活在PP人口普查区（大多数是拉丁美洲人）。项目2与合作推广系统合作， 解决位于PP人口普查区的美国印第安人社区中的肥胖预防和SDOH问题， 蒙大拿州、俄勒冈州、南达科他州和威斯康星州（所有人口普查区域都是农村/边境）。这两个项目包括 项目指导委员会和项目2包括每个社区的地方社区咨询委员会。 在HC 2活动和研究中创造协同作用的一个首要主题是增加“通过 公平执行”。因此，HC 2实施战略是专门针对当地和 社区背景。HC 2的结构和功能为促进癌症预防创造了实质性的协同作用 通过以下方式对持续贫困的地区和人口进行研究： 经验，社区参与和跨机构的领导力;创新，全面，多 一级的概念框架，目标是通过公平执行实现目标，并有共同的研究重点 多方面的，跨机构的培训计划，利用 互补的优势和获得培训生人口横跨犹他州和蒙大拿州;和，结合深 以及广泛的社区参与和跨机构的强大伙伴关系，以创建HC 2网络， 这将有助于弥合科学发现和EBI在PP领域的实施之间的差距。在 总之，HC 2将建立在现有专业知识、研究基础设施和长期合作伙伴关系的基础上， 在PP领域的社区参与癌症预防和控制研究的区域和国家领导者。