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Mentoring in community engaged implementation research to reduce cardiovascular disparities

指导社区参与实施研究以减少心血管差异

基本信息

批准号：
10671467
负责人：
NAMRATHA R KANDULA
金额：
$ 12.15万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-01 至 2026-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10671467
关键词：
Acceleration Address Adolescent Adult Affect American Heart Association Asian Americans Atherosclerosis Behavior Blood Pressure Cardiovascular Diseases Cardiovascular system Clinical Clinical Research Communities Daughter Diabetes Mellitus Diet Disparity Disparity population East Asian Education Effectiveness Effectiveness of Interventions Enrollment Environment Equity Ethnic Population Evaluation Evidence based intervention Family Female Adolescents Funding Future Gender Glucose Goals Health Health Educators Heart Diseases High Prevalence Hispanic Populations Hypertension Immigrant Immigration Income Individual Infrastructure Intervention Intervention Trial Investments Knowledge Language Leadership Link Lipids Measures Mediator Medicine Mentors Mentorship Methods Midcareer Investigator Award in Patient-Oriented Research Minority Modeling Mothers National Heart, Lung, and Blood Institute Neighborhood Health Center Neighborhoods Not Hispanic or Latino Outcome Participant Physical activity Population Prevention strategy Preventive Medicine Public Health Research Research Methodology Research Personnel Resources Risk Factors Scholarship Science South Asian Testing Time Training United States United States National Institutes of Health Universities Vulnerable Populations Weight Woman Work cardiovascular disorder prevention cardiovascular disorder risk cardiovascular health community based participatory research community burden community engaged research community engagement community partnership community setting contextual factors disease disparity effectiveness evaluation effectiveness outcome epidemiology study evidence base exercise intervention future implementation health care availability health disparity health disparity populations health equity healthy lifestyle high risk hybrid type 1 design implementation evaluation implementation outcomes implementation research implementation science implementation strategy improved innovation lifestyle intervention medical schools men mid-career faculty mortality next generation physical inactivity practice setting racial population research to practice skills social social determinants social health determinants stakeholder perspectives structural determinants student mentoring treatment research

项目摘要

PROJECT SUMMARY This is a proposal for a K24 Midcareer Investigator Award in Patient-Oriented Research (POR) for Namratha Kandula, MD, MPH of Northwestern University Feinberg School of Medicine. Dr. Kandula is Associate Professor of Medicine and Preventive Medicine and co-Director of the Center for Community Health. Dr. Kandula's scholarship is focused on understanding the social and cultural determinants of cardiovascular disease (CVD) disparities in South Asian Americans and implementing evidence-based interventions (EBIs) using community-based participatory research (CBPR) methods. South Asian Americans, the majority of whom are immigrants, are disproportionately affected by CVD compared to non-Hispanic whites and other Asian Americans. While there is ample evidence that intensive diet and physical activity interventions improve CVD risk factors in adults, these EBIs have limited reach in South Asian and other vulnerable populations because most EBIs were developed in narrow clinical populations, lack cultural salience, do not account for multilevel social determinants of health, and are difficult to implement in new settings. Dr. Kandula has expertise in epidemiologic studies and community-based lifestyle intervention trials and has been actively mentoring students and junior investigators on health disparities and community engaged research. The objective of this K24 application is to promote science and mentorship in community engaged implementation research to optimally deliver and sustain EBIs focused on populations with a high burden of health disparities. Support from the K24 will provide Dr. Kandula with protected time to: 1) Devote more time to mentoring a diverse group of young investigators in community engaged implementation research; 2) Improve her implementation science research and mentoring skills through mentor training and guidance from senior mentors; 3) Extend her currently funded work to fill critical gaps in the science of delivering and sustaining EBIs for vulnerable populations; and 4) Assume leadership in new multisector, collaborative research on how to optimally deliver EBIs to eliminate health disparities. The current K24 proposal builds upon the scientific premise and extends the research and mentorship of the PI in the context of her two NIH-funded, community engaged lifestyle intervention trials to reduce CVD disparities in South Asian adults and adolescents (SAHELI and SAATH trials). The PI and her mentees will use mixed methods to: 1) Investigate social and structural determinants that contributed to differences in implementation outcomes of EBIs in the SAHELI and SAATH trials; 2) Evaluate sustainability of the EBIs implemented in the SAHELI and SAATH trials; and 3) Understand stakeholder perspectives on which implementation outcomes and evaluation strategies are most meaningful and feasible when implementing EBIs for CVD prevention in health disparity populations. Conduct of the proposed Aims will accelerate science and mentorship in building sustainable community partnerships and models to optimally deliver EBIs that improve the health of vulnerable populations and advance health equity.

项目总结