权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Research Training in the Neuroscience of Aging

衰老神经科学研究培训

基本信息

批准号：
10672196
负责人：
Joseph Michael Castellano
金额：
$ 32.12万
依托单位：
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-01 至 2025-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10672196
关键词：
Aging Neurosciences Research Training

项目摘要

Project Summary The program on Research Training in the Neuroscience of Aging provides predoctoral students in Neuroscience with an integrated training experience in the laboratories of nationally and internationally recognized faculty. The predoctoral training program builds on an exciting, translationally relevant curriculum taught in years one and two of graduate school that has been awarded NIH support through the Jointly Sponsored Predoctoral Early Stage T32 Training Program mechanism (T32 MH087004). This training program is the first at Mount Sinai to focus specifically on the neuroscience of aging and age-related neurodegenerative diseases (primarily Alzheimer's disease), complementing Mount Sinai's historical concentration and strength in research in these areas. Outstanding training faculty in this program share common research interests in the mechanisms of brain function in health and disease, employing a diversity of experimental approaches and working at levels of analysis ranging from molecular neurobiology to human neuropsychology and neuroimaging. The training program specifically encourages participation of faculty mentors whose research grants directly focus on aging neuroscience research, while not excluding those whose research expertise is critically important for the interdisciplinary training we seek to impart. Through their coursework, predoctoral trainees will have received a solid foundation in basic neurobiology and the pathophysiology of neurological and psychiatric diseases, as well as biostatistics and the responsible conduct of research. Advanced coursework includes two seminar courses, one on the biology of aging and one on the neuroscience of aging, complementing the broad foundational coursework in neuroscience. Selection of a research mentor is made in a collaborative environment that actively promotes multidisciplinary, integrative research. Research training also has a ‘work in progress’ component, to foster important interdisciplinary interactions, hone presentation and writing skills, and improve awareness of ethical issues. This program began in September of 2015 with 4 predoctoral training slots and to date has supported 8 students, 2 of whom have already competed their PhD training. Using this approach, the program on Research Training in the Neuroscience of Aging provides predoctoral students with the guidance and experimental tools, in the laboratories of our training faculty, to launch successful, productive, and independent careers in aging research.

项目摘要在老龄化的神经科学研究培训计划提供神经科学的博士前学生在国内和国际公认的教师实验室的综合培训经验。的博士前培训计划建立在一个令人兴奋的，专业相关的课程，在第一年教授，两所研究生院已通过联合赞助的博士前早期获得NIH的支持阶段T32培训计划机制（T32 MH087004）。这个培训项目是西奈山第一个专注于衰老和与年龄相关的神经退行性疾病的神经科学（主要是阿尔茨海默氏症），补充西奈山的历史浓度和研究实力，在这些地区该项目的优秀培训教师在脑机制方面有着共同的研究兴趣在健康和疾病中发挥作用，采用多种实验方法，分析范围从分子神经生物学到人类神经心理学和神经成像。培训该计划特别鼓励教师导师的参与，他们的研究赠款直接集中在老龄化上神经科学研究，同时不排除那些研究专业知识是至关重要的，跨学科的培训，我们寻求传授。通过他们的课程，博士前学员将获得一个在基础神经生物学和神经和精神疾病的病理生理学的坚实基础，以及作为生物统计学和负责任的研究行为。高级课程包括两门研讨课程，一个关于衰老的生物学，一个关于衰老的神经科学，补充了广泛的基础知识，神经科学课程研究导师的选择是在一个积极的协作环境中进行的，促进多学科、综合研究。研究培训还有一个“正在进行的工作”部分，培养重要的跨学科互动，磨练演讲和写作技巧，提高对伦理问题该计划于2015年9月开始，有4个博士前培训名额，迄今已资助了8名学生，其中2人已经完成了博士培训。通过这种方法，该方案研究培训在衰老的神经科学提供了指导，实验工具，在我们的培训教师的实验室，推出成功的，富有成效的，和独立的从事老龄化研究

项目成果

期刊论文数量（11）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Memories light the corners of my mind.

回忆照亮了我心灵的角落。

DOI：
10.1038/s41593-019-0390-7
发表时间：
2019
期刊：
Nature neuroscience
影响因子：
25
作者：
Baxter,MarkG;Upright,NicholasA
通讯作者：
Upright,NicholasA

Multimodal Assessment of Bottlenose Dolphin Auditory Nuclei Using 7-Tesla MRI, Immunohistochemistry and Stereology.

DOI：
10.3390/vetsci9120692
发表时间：
2022-12-13
期刊：
Veterinary sciences
影响因子：
2.4
作者：
Orekhova K;Selmanovic E;De Gasperi R;Gama Sosa MA;Wicinski B;Maloney B;Seifert A;Alipour A;Balchandani P;Gerussi T;Graïc JM;Centelleghe C;Di Guardo G;Mazzariol S;Hof PR
通讯作者：
Hof PR

Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity.

DOI：
10.1016/j.isci.2023.107525
发表时间：
2023-09-15
期刊：
ISCIENCE
影响因子：
5.8
作者：
Sarrafha, Lily;Neavin, Drew R.;Parfitt, Gustavo M.;Kruglikov, Ilya A.;Whitney, Kristen;Reyes, Ricardo;Coccia, Elena;Kareva, Tatyana;Goldman, Camille;Tipon, Regine;Croft, Gist;Crary, John F.;Powell, Joseph E.;Blanchard, Joel;Ahfeldt, Tim
通讯作者：
Ahfeldt, Tim

Navigating Social Space.