HIV and Substance Use Cohort Coordinating Center for Emerging and High Impact Scientific Cross Cohort Studies: HIV SUCCESS
HIV and Substance Use Cohort Coordinating Center for Emerging and High Impact Scientific Cross Cohort Studies: HIV SUCCESS
批准号:
10676432
负责人:
GEETANJALI CHANDER
金额:
$93.9万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-04-01 至 2028-03-31
关键词:
AbbreviationsAccelerationAcquired Immunodeficiency SyndromeAddressAdherenceAgingAmericanAreaAwardBiological MarkersBiological Specimen BanksBiometryCOVID-19 riskCaringClinicalClinical InformaticsCodeCohort StudiesCollaborationsCommunitiesComplexDataData AnalysesData CollectionData LinkagesData ScienceData SourcesDevelopmentDisparateDisparityDissemination and ImplementationDocumentationDrug usageEnsureEpidemicEpidemiologistEpidemiologyEvaluationFundingFutureFuture GenerationsGenerationsGeneticHIVHIV/AIDSHealthIndividualInfrastructureInfusion proceduresInterventionKnowledgeLeadershipLearningLinkLongitudinal cohortMentorsMentorshipMethamphetamineMethodologyMolecular EpidemiologyNational Institute of Drug AbuseNorth AmericaOpioidOutcomePatient Outcomes AssessmentsPatternPersonsPopulationPopulation HeterogeneityPositioning AttributePrevalenceProviderPublic HealthPublic Health InformaticsPublicationsPublishingRegimenResearchResearch PersonnelResearch PriorityResourcesRiskRisk FactorsRunningRuralScientistSiteStatistical MethodsStimulantSubgroupSystemTarget PopulationsTestingTrainingTranslationsUnited StatesWorkadjudicationantiretroviral therapyclinical careclinical epidemiologyclinical research sitecohortcomorbiditydata harmonizationdata integrationdata managementdata repositorydata toolsdesignexperiencehealth dataimplementation interventionimprovedinformatics infrastructureinnovationmethod developmentmultidisciplinaryopioid epidemicopioid usepre-exposure prophylaxisprogramsprotocol developmentsocial health determinantsspellingsubstance usesubstance use treatmentsyndemictooltool developmenttransmission processuptakeweb siteworking group
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The purpose of the HIV and Substance Use Cohort Coordinating Center for Emerging and High Impact
Scientific Cross Cohort Studies: HIV SUCCESS is to support National Institute on Drug Abuse funded cohorts
as they implement research strategies to better understand and address substance use and its consequences
among people with HIV (PWH). Substance use prevalence among PWH is high, and substance use patterns,
including increasing concurrent methamphetamine/opioid use as part of the 4th wave of the opioid epidemic,
continue to evolve. Substantial challenges remain to improve understanding and implementation of
interventions to address substance use and its impacts among PWH. Addressing these challenges is the
overarching purpose of the cohorts and requires a coordinating center (CC) experienced in data integration
and harmonization, health informatics, multi-site coordination, clinical care and intervention experience, and
HIV and substance use research to support the cohorts and comprehensively integrate cross-cohort data. The
resulting resource of comprehensively integrated data will give researchers the potential to address important
scientific and public health questions that would otherwise not be possible in individual cohorts. We will work
with cohorts to allow complex, careful and complete analyses of outcomes and results across diverse
populations using harmonized data. We will bring in data from other cohorts and studies as needed to ensure
that adequate clinical, biomarker, and/or genetic data are available to address key questions. Careful data
harmonization where appropriate will improve the statistical power to identify areas or sub-groups for research
focus and to understand what interventions are proving successful in the broader context of the whole
population of PWH (as opposed to the target population of a single cohort). This team brings vast experience
with HIV cohort data; data linkage and harmonization; methods development; statistical support including
causal inference from longitudinal observational data; health informatics platform and tool infrastructure and
development including data repositories and tools for efficient and accurate electronically collected patient
reported outcomes and outcomes adjudication; providing overall coordination for large collaborations of
cohorts and studies; a strong background in clinical epidemiology of HIV and substance use; and expertise in
applying this information to clinical care and interventions. We also have a comprehensive mentoring approach
to develop a new generation of HIV and substance use researchers. We will support cohorts to enhance data
collection where appropriate, merge and harmonize data when feasible, and work together to address key
questions on HIV, substance use, and outcomes that cannot be addressed by individual cohorts. By providing
project management, mentorship, and support, as well as developing a robust data repository, and
accomplishing the integration and linkage of data, we will achieve a multi-disciplinary integrated network with
multi-site data with sufficient sizes needed to address substance use and its impacts among PWH.
期刊论文(0)
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会议论文
Training in Equity and Structural Solutions in Addictions (TESSA)
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批准号:10625735
-
项目类别:
-
资助金额:$19.36万
-
财政年份:2023
-
负责人:GEETANJALI CHANDER
-
依托单位:
Mentoring and Patient Oriented Research at the Nexus of Unhealthy Alcohol Use and HIV
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批准号:10608555
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项目类别:
-
资助金额:$17.39万
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财政年份:2022
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负责人:GEETANJALI CHANDER
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依托单位:
Mentoring and Patient Oriented Research at the Nexus of Unhealthy Alcohol Use and HIV
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批准号:10685992
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项目类别:
-
资助金额:$16.86万
-
财政年份:2022
-
负责人:GEETANJALI CHANDER
-
依托单位:
Alcohol Research Consortium in HIV: Implementation Research Arm
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批准号:10304375
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项目类别:
-
资助金额:$69.5万
-
财政年份:2021
-
负责人:GEETANJALI CHANDER
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依托单位:
Alcohol Research Consortium in HIV: Ending the HIV Epidemic through interventions and Epidemiology at the intersection of the alcohol and HIV care Continua
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批准号:10304371
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项目类别:
-
资助金额:$145.48万
-
财政年份:2021
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负责人:GEETANJALI CHANDER
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依托单位:
Alcohol Research Consortium in HIV: Administrative Core
-
批准号:10304372
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项目类别:
-
资助金额:$14.68万
-
财政年份:2021
-
负责人:GEETANJALI CHANDER
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依托单位:
Impact of alcohol reduction on Tuberculosis drug levels, TB adherence and gut microbiome
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批准号:10544859
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项目类别:
-
资助金额:$10.79万
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财政年份:2020
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负责人:GEETANJALI CHANDER
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依托单位:
Hybrid trial for Alcohol reduction among people with TB and HIV in India (HATHI)
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批准号:10658901
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项目类别:
-
资助金额:$59.11万
-
财政年份:2020
-
负责人:GEETANJALI CHANDER
-
依托单位:
Hybrid trial for Alcohol reduction among people with TB and HIV in India (HATHI)
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批准号:10252751
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项目类别:
-
资助金额:$60.45万
-
财政年份:2020
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负责人:GEETANJALI CHANDER
-
依托单位:
Hybrid trial for Alcohol reduction among people with TB and HIV in India (HATHI)
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批准号:10435573
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项目类别:
-
资助金额:$58.25万
-
财政年份:2020
-
负责人:GEETANJALI CHANDER
-
依托单位:
Mentoring and Patient Oriented Research at the Nexus of Unhealthy Alcohol Use and HIV
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批准号:10247600
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项目类别:
-
资助金额:$1.93万
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财政年份:2019
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负责人:GEETANJALI CHANDER
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依托单位:
Using CBPR to Engage Hazardous Drinking Women in the HIV Prevention and Care Continuum
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批准号:9768880
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项目类别:
-
资助金额:$19.42万
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财政年份:2017
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负责人:GEETANJALI CHANDER
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依托单位:
1/3 Alcohol Research Consortium in HIV - Administrative Core (ARCH-AC)
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批准号:10426405
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项目类别:
-
资助金额:$11.11万
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财政年份:2011
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负责人:GEETANJALI CHANDER
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依托单位:
1/3 Alcohol Research Consortium in HIV - Administrative Core (ARCH-AC)
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批准号:9206261
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项目类别:
-
资助金额:$26.96万
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财政年份:2011
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负责人:GEETANJALI CHANDER
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依托单位:
1/3 Alcohol Research Consortium in HIV - Administrative Core (ARCH-AC)
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批准号:9341058
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项目类别:
-
资助金额:$26.93万
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财政年份:2011
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负责人:GEETANJALI CHANDER
-
依托单位:
1/3 Alcohol Research Consortium in HIV - Administrative Core (ARCH-AC)
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批准号:10161321
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项目类别:
-
资助金额:$11.24万
-
财政年份:2011
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负责人:GEETANJALI CHANDER
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依托单位:
1/3 Alcohol Research Consortium in HIV - Administrative Core (ARCH-AC)
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批准号:9767519
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项目类别:
-
资助金额:$24.82万
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财政年份:2011
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负责人:GEETANJALI CHANDER
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依托单位:
Computerized BI for Binge Drinking HIV At-Risk & Infected African-American Women
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批准号:8307379
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项目类别:
-
资助金额:$44.0万
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财政年份:2009
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负责人:GEETANJALI CHANDER
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依托单位:
Computerized BI for Binge Drinking HIV At-Risk & Infected African-American Women
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批准号:7942033
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项目类别:
-
资助金额:$43.19万
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财政年份:2009
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负责人:GEETANJALI CHANDER
-
依托单位:
Computerized BI for Binge Drinking HIV At-Risk & Infected African-American Women
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批准号:7841445
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项目类别:
-
资助金额:$42.14万
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财政年份:2009
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负责人:GEETANJALI CHANDER
-
依托单位:
海外基金