Disaster Research Response (DR2) Core

灾难研究响应 (DR2) 核心

• 批准号: 10707491
• 负责人: Thomas Joseph McDonald
• 金额: $ 9万
• 依托单位: TEXAS A&M UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10707491
• 关键词: Address; Analytical Chemistry; Basic Science; Catalogs; Certification; Collection; Communities; Community of Practice; Complex; Consultations; Data; Data Analyses; Databases; Decision Making; Dedications; Dependence; Dimensions; Disasters; Documentation; Electronics; Emergency Situation; Ensure; Environment; Equipment; Event; Exposure to; Faculty; Fire - disasters; Freeze Drying; Funding; Future; Hazardous Substances; Hazardous Waste Operations and Emergency Response; Health; Human; Human Resources; Hurricane; Industrialization; Infrastructure; Laboratories; Learning; Life; Measures; Methods; Modeling; Nongovernmental Organizations; Procedures; Process; Protocols documentation; Records; Reproducibility; Research; Resources; Risk; Safety; Sampling; Science; Services; Site; Soil; Superfund; System; Techniques; Technology; Testing; Texas; Time; Time trend; Training; Translating; Translational Research; Translations; Transportation; United States National Institutes of Health; Universities; Work; community engagement; data management; design; environmental chemistry; experience; experimental study; improved; innovation; instrumentation; laboratory equipment; method development; programs; quality assurance; repository; response; sample collection; tool; translational engagement; water sampling

Disaster Research Response (DR2) Core ABSTRACT The overall theme of the Texas A&M University Superfund Research Center is to develop, apply, and translate a comprehensive set of tools and models that will aid in mitigating the human health consequences of exposure to hazardous mixtures during environmental emergency-related contamination events. In the past funding period (since 2017), the Center responded to a number of disasters to collect samples and respond to concerns from community partners, non-governmental organizations, and local and state agencies. Activities included sampling of water, sediment, and soils in response to Hurricane Harvey (2017), Hurricane Florence (2018), and the large- scale industrial fire at the Intercontinental Terminals Company (ITC) facility (2019). Sampling was conducted to establish both spatial and temporal dimensions of the extent of re-distribution of hazardous substances in the environment that may impact human health. While several of the Texas A&M University Superfund Research Center’s projects and cores have contributed to these efforts and provided sampling supplies, field personnel, training, and quality assurance/control (QA/QC) documentation, we now propose to establish a dedicated service core for these activities. Therefore, this new DR2 Core will support the Center, and the rigor and reproducibility of its DR2 activities, by ensuring the Center’s ability to respond to disasters through creation of a centralized resource to support DR2 infrastructure, methods, supplies, and training. The central hypothesis of the DR2 Core is that the rigor and reproducibility of DR2 activities will be ensured and the Center’s ability to respond to future disasters with translational research will be improved by creating a centralized resource and infrastructure to support disaster research response encompassing environmental assessment capabilities that can be rapidly deployed anywhere. The DR2 Core responds to Superfund mandate (3), the development of methods and technologies to detect hazardous substances in the environment, and will focus on four specific Aims. First, the DR2 Core will maintain sampling supplies, field and laboratory equipment, and instrumentation required for collection of environmental samples during and after disasters. Second, the DR2 Core will coordinate collection, processing, and storage of environmental samples. Third, this Core will facilitate DR2 activities by the projects and cores and integrate with NIH DR2 programs. Finally, the DR2 Core will ensure that Center personnel can conduct fieldwork safely and properly for baseline sampling and in response to disasters. Overall, the efforts of the DR2 Core will specifically enhance interactions among Center projects and other cores, increasing their impact by ensuring alignment of measured/human/test system exposures from real-life environmental samples and increasing the translation of basic science in decision making, translation, and community engagement.

灾难研究响应（DR 2）核心摘要 德州农工大学超级基金研究中心的总体主题是开发、应用和翻译 一套全面的工具和模型，将有助于减轻暴露对人类健康的影响 在与环境紧急情况有关的污染事件中，在过去的资助期间， （自2017年以来），该中心应对了一些灾难，收集样本并回应了来自 社区伙伴、非政府组织以及地方和国家机构。活动包括取样 水，沉积物和土壤响应飓风哈维（2017年），飓风佛罗伦萨（2018年），和大- 洲际码头公司（ITC）设施的规模工业火灾（2019年）。取样的目的是 确定危险物质在全球范围内重新分布的空间和时间范围， 可能影响人类健康的环境。虽然德克萨斯A&M大学超级基金研究的几个 中心的项目和核心为这些努力做出了贡献，并提供了取样用品、现场人员， 培训和品质保证/控制文件，我们现建议设立一个专责服务， 这些活动的核心。因此，这款新的DR 2 Core将支持中心， 其DR 2活动，通过建立一个集中的 支持DR 2基础设施、方法、供应和培训的资源。DR 2核心的核心假设 DR 2活动的严谨性和可重复性将得到确保，中心应对未来挑战的能力将得到加强。 将通过建立集中的资源和基础设施来改善灾害转化研究， 支持灾害研究反应，包括环境评估能力， 部署在任何地方。DR 2核心响应超级基金任务（3），方法的开发和 该项目将重点关注四个具体目标。一是 DR 2核心将维护取样供应品、现场和实验室设备以及 在灾害期间和灾害后收集环境样本。第二，DR 2核心将协调收集， 环境样品的处理和储存。第三，该核心文件将促进项目开展DR 2活动， 和核心，并与NIH DR 2程序集成。最后，DR 2核心将确保中心人员能够 安全和适当地进行实地工作，以进行基线取样和应对灾害。总的来说， DR 2核心将特别增强中心项目和其他核心之间的相互作用， 通过确保实测/人体/测试系统暴露与实际环境样本的一致性来产生影响 增加基础科学在决策、翻译和社区参与中的翻译。