Multidisciplinary Training in Cancer Research

描述(由申请人提供)：我们建议的培训计划专门针对癌症研究领域的博士后学生和博士后研究员进行多学科培训。为了实现这一目标，我们开发了一个跨学科的癌症培训计划，该计划将把信号转导、基因结构和功能、受体生物学、DNA修复、结构生物学、生物工程和药物发现方面已经建立和成功的计划与临床暴露结合在一起。学生和研究员将接受积极参与基础科学癌症研究和前沿临床应用的专家教师的实验室培训和教学指导。此外，我们的目标是，我们的学生和研究员也将被培养成科学界的积极成员，他们能够清楚地交流想法，批判性地评估生物医学研究，并在科学学术方面指导其他人。 我们汇集了来自9个不同部门和多个学科的31名培训人员。这是一个由基础研究人员和临床科学家组成的具有凝聚力和协作性的团队，他们毕生致力于癌症患者的基本发现和治疗。在过去的10年里，我们的项目教师培训了112名博士后和180名博士后研究员，他们拥有指导这群受训人员以真正多学科方式进行研究的经验和跨学科重点。我们希望我们的学生和研究员能够熟练地利用传统的假设驱动的方法以及以发现为导向的实验设计来探索这些问题。最终目标是培养一批未来的科学家，他们可以参与分子生物学、基因组学/蛋白质组学、生物工程和临床护理的交叉，成为综合和团队方法的领导者，了解癌症的复杂问题，因为它与潜在的预防和创新治疗策略有关。此外，UTMB在培训少数族裔医生、研究人员和学生方面处于全国领先地位，因此，我们计划的另一个目标是利用现有的计划，确保我们正在培训不同背景和种族的个人，以更好地服务于我们多样化的社会。

DESCRIPTION (provided by applicant): Our proposed training program is specifically focused on the multidisciplinary training of predoctoral students and postdoctoral fellows in the field of cancer research. To achieve this goal we have developed an interdisciplinary cancer training program which will synthesize already established and successful programs in signal transduction, gene structure and function, receptor biology, DNA repair, structural biology, bioengineering and drug discovery with clinical exposure into one cohesive program. Students and fellows will receive laboratory training and didactic instruction from expert faculty actively involved in both basic science cancer research and leading edge clinical applications. Moreover, it is our goal that our students and fellows will also be trained to function as active members of the scientific community who can clearly communicate ideas, critically evaluate biomedical research and mentor others in scientific scholarship. We have assembled 31 training faculty from 9 different departments and multiple disciplines. This cohesive and collaborative group of basic researchers and clinician scientists who are dedicated to a lifetime of basic discovery and treatment of cancer patients. In the past 10 years our program faculty has trained 112 predoctoral and 180 postdoctoral fellows and has the experience as well as the interdisciplinary focus to guide this group of trainees to function in teams pursuing research in a truly multidisciplinary fashion. We want our students and fellows to be adept at utilizing traditionally hypothesis driven methods as well as discovery oriented experimental designs to explore these problems. The ultimate goal is to develop a cadre of future scientists who can participate at the intersection of molecular biology, genomics/proteomics, bioengineering and clinical care to become leaders in integrative and team approaches to understand the complex issues of cancer as it relates to potential prevention and innovative treatment strategies. In addition, UTMB is a national leader in the training of minority physicians, researchers and students and, therefore, another goal of our program is to utilize established programs to ensure that we are training individuals of diverse backgrounds and ethnicities to better serve our diverse society.