Diversity supplement to R00AG071838: Well-being as a Protective Factoragainst Cognitive Decline and Dementia

项目摘要 这一行政补充将提供18个月的学士学位后研究培训 佩顿规则根据母项目R 00 AG 071838：嗯- 作为一个保护因素对认知能力下降和痴呆症（PI：博士Willlroth）。女士 鲁尔在纽约大学获得哲学-神经科学-心理学学士学位， 圣路易斯的华盛顿大学于2022年5月，并一直与Willroth博士和 博士从那时起，帕特里克希尔担任兼职实验室经理。鲁尔女士的最终目标是好好学习- 残疾/慢性病老年人的生存和恢复能力。与她的事业相一致 调查残疾人的幸福感和复原力的目标， 幸福感作为一种保护因素，破坏了流动性之间的双向联系 残疾和认知能力下降。补充目标将通过审查两个 数据集，拉什地图和火星，这两个解决移动性残疾利用罗索- 布雷斯劳量表。与母公司R 00类似，将采用多个纵向结构方程模型， 用于检查行动不便和 认知能力下降此外，将引入各种类型的福祉作为主持人， 测试是否较高水平的某些类型的福祉可能会减轻的强度， 运动障碍和认知能力下降之间的关系。本补充文件还将涉及 Rule女士的职业培训目标，包括定量方法、科学手稿和 补助金写作，以及认知老化和残疾研究方面的专业知识。补充的目的 解决促进科学研究的多样性NIH的目标，并将大大提高女士。 Rule在该领域的职业发展。

Project Summary This administrative supplement will provide an 18-month postbaccalaureate research training and mentorship program for Ms. Payton Rule under the parent project R00AG071838: Well- being as a Protective Factor against Cognitive Decline and Dementia (PI: Dr. Willlroth). Ms. Rule received her undergraduate degree in Philosophy-Neuroscience-Psychology at Washington University in St. Louis in May of 2022 and has been working with Dr. Willroth and Dr. Patrick Hill as a part-time lab manager since then. Ms. Rule’s ultimate goal is to study well- being and resilience among people aging with disability/chronic illness. In line with her career goals to investigate well-being and resilience in people with disabilities, Ms. Rule will examine well-being as a protective factor that disrupts bidirectional associations between mobility disability and cognitive decline. The supplement aims will be addressed by examining two datasets, Rush MAP and MARS, which both address mobility disability utilizing the Rosow- Breslau scale. Similar to the parent R00, multiple longitudinal structural equation models will be employed to to examine potential bidirectional associations between mobility disability and cognitive decline. Furthermore, various types of well-being will be introduced as moderators to test whether higher levels of certain types of well-being may mitigate the strength of the association between mobility disability and cognitive decline. This supplement will also address career training goals for Ms. Rule, including quantitative methods, scientific manuscript and grant writing, and expertise in cognitive aging and disability studies. The aims of the supplement address the NIH goals of promoting diversity in scientific research and will strongly enhance Ms. Rule’s career development within the field.