Diversity supplement to R00AG071838: Well-being as a Protective Factoragainst Cognitive Decline and Dementia

项目摘要 本行政副刊将提供为期18个月的毕业后研究培训。 和Payton Rule女士在母公司项目R00AG071838下的指导计划：嗯- 作为认知衰退和痴呆症的保护因素(PI：Willlroth博士)。女士。 鲁尔获得哲学-神经科学-心理学学士学位 2022年5月在圣路易斯的华盛顿大学，他一直在与威罗斯博士和 帕特里克·希尔博士从那时起担任兼职实验室经理。鲁尔女士的最终目标是学习好-- 残疾/慢性病老年人的生存能力和复原力。与她的事业相一致 调查残疾人幸福感和韧性的目标，鲁尔女士将研究 幸福感是破坏流动之间双向联系的保护性因素 残疾和认知能力下降。附录的目标将通过审查两个 数据集，Rush MAP和MARS，这两个数据集都利用Rosow解决了行动障碍- 布雷斯劳等级。与父R00类似，多个纵向结构方程模型将 用来研究行动不便和行动不便之间潜在的双向联系 认知能力下降。此外，将引入各种类型的福祉作为主持人，以 测试较高水平的某些类型的幸福感是否可以缓解 行动不便与认知功能减退之间的关系。本副刊还将讨论 鲁尔女士的职业培训目标，包括量化方法、科学手稿和 授予写作，以及认知老化和残疾研究方面的专业知识。这份副刊的目的 解决美国国立卫生研究院促进科学研究多样性的目标，并将大力加强MS。 规则在该领域内的职业发展。

Project Summary This administrative supplement will provide an 18-month postbaccalaureate research training and mentorship program for Ms. Payton Rule under the parent project R00AG071838: Well- being as a Protective Factor against Cognitive Decline and Dementia (PI: Dr. Willlroth). Ms. Rule received her undergraduate degree in Philosophy-Neuroscience-Psychology at Washington University in St. Louis in May of 2022 and has been working with Dr. Willroth and Dr. Patrick Hill as a part-time lab manager since then. Ms. Rule’s ultimate goal is to study well- being and resilience among people aging with disability/chronic illness. In line with her career goals to investigate well-being and resilience in people with disabilities, Ms. Rule will examine well-being as a protective factor that disrupts bidirectional associations between mobility disability and cognitive decline. The supplement aims will be addressed by examining two datasets, Rush MAP and MARS, which both address mobility disability utilizing the Rosow- Breslau scale. Similar to the parent R00, multiple longitudinal structural equation models will be employed to to examine potential bidirectional associations between mobility disability and cognitive decline. Furthermore, various types of well-being will be introduced as moderators to test whether higher levels of certain types of well-being may mitigate the strength of the association between mobility disability and cognitive decline. This supplement will also address career training goals for Ms. Rule, including quantitative methods, scientific manuscript and grant writing, and expertise in cognitive aging and disability studies. The aims of the supplement address the NIH goals of promoting diversity in scientific research and will strongly enhance Ms. Rule’s career development within the field.