HIV CO-INFECTIONS IN UGANDAAdministrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional)

背景：了解研究伦理原则及其实际应用， 在卫生学科培训的课程要求中没有一贯地纳入理论。 在资源有限的环境中对艾滋病毒感染者（PLWH）进行的研究可能会造成 此外，生物伦理学方面的挑战，培训生必须接触研究 开展研究活动前的生物伦理培训 瞄准我们计划开发一个培训计划，采用课堂培训， 制定角色扮演和案例情景，以及基于网络的模块，以弥补差距， 使马凯雷雷大学医学院的学员掌握伦理知识 与PLWH研究的原则。 具体目标1.了解研究生在研究生物伦理学方面的培训需求， 艾滋病毒和合并感染领域。2.发展短期培训课程，包括课堂培训， 包括角色扮演和案例情景以及网上培训单元， 医学院3.对开发的培训进行试点和评估，完善和完善 教材和内容。在授予结束时，这些内容将正式移交给 医学院和课程将每年提供（后奖）作为学校的一部分 医学培训。 方法 我们计划进行一个形成阶段，包括对学员的调查和深入访谈， 并与导师协调培训材料和培训的实施。 调查结果将指导培训材料和内容的制定，重点是复杂的 以及艾滋病毒携带者中未充分研究的人群，如儿童、青少年、孕妇和哺乳期妇女 妇女、感染艾滋病毒的老年人、“高危人群”（例如商业性工作者， 性少数男性、变性人、吸毒者）和重病住院患者。 我们将组织一个试点培训班，然后进行正式评估，包括调查和 与学员的面谈。根据反馈意见，培训计划将得到完善， 最后定稿，并将纳入医学院的教学单元

Background: Knowledge of research ethics principles and their practical application and ethical theory are not consistently integrated in curriculum requirements in health disciplines training. Research in people living with HIV (PLWH) in resource limited settings (RLS) may pose additionally bioethical challenges for which it is imperative that trainees are exposed to research bioethical training before carrying out research activities Aim. We plan to develop a training program with a blended approach of class training, development of role-plays and case scenarios, and web-based modules to address gaps and equip trainees of the School of Medicine at Makerere University with knowledge in ethics principles in research with PLWH. Specific objectives 1. To understands the training needs in research bioethics for trainees in the area of HIV and co-infections. 2.To develop a short training curriculum comprising class training, including role plays and case scenarios and web-based modules for online training for trainees at the School of Medicine. 3.To pilot and evaluate the developed training, refine and complete the teaching material and content. At the end of the grant this content will be officially handed over to the School of Medicine and the course will be offered annually (post award) as part of the School of medicine training. Methods We plan to conduct a formative phase consisting in a survey of trainees, and in depth interviews, and coordinate the training material with the mentors and the implementation of the training. The findings will guide the development of the training material and content, focusing on complex and understudied populations within PLWH, such as children, adolescents, pregnant and lactating women, elderly people living with HIV, “most at risk population” (e.g. commercial sex workers, sexual minority men, transgender individuals, drug users), and very sick hospitalized patients. We will organize a pilot training course followed by a formal evaluation consisting of a survey and interviews with the trainees. Based on the feedback the training program will be refined and finalized and will be integrated in the teaching modules of the School of Medicine