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中文摘要
翻译
NEI视觉研究核心助学金的总体目标是促进申请 在结构、功能和疾病分析中的重要技术 影响视觉系统的机制。调查人员的长期目标是 这笔赠款用于预防失明和恢复视力。为此,我们将制定 一系列核心模块,将提供最先进的仪器和 视觉研究所需的技术。这三个核心模块是:(1)眼科 成像模块;(2)功能视觉模块;(3)分子信息学模块。 这些模块包含将由高技能人员维护和操作的设备 由R01资助的现有调查人员监督的技术人员。正在巩固 这些模块中的这些技术使我们能够将这些技术和技能带给所有人 我们计划中的潜在用户,我们预计这将提高用户的工作效率 实验室,避免设备和工作的重复。这些项目的成功运作 三个模块将把这些最好的技术带到每个NEI RO1 支持该机构的实验室。我们还设想这些核心模块将 加强和维持协作的科学环境,这是 由这些模块支持的课题组。这些模块还将增强 提高工作效率,增加参与调查人员之间的协作。这些 模块还将允许初级调查人员获得服务和研究 有助于生成初步数据以支持新RO1应用的策略。
英文摘要
The overall aim of this NEI Core Grant for Vision Research is to facilitate the application of important technologies in the analysis of the structure, function and disease mechanisms that affect the visual system. The long-term goal of the investigators served by this grant is to preventing blindness and restoring vision. To this end we will develop a series of core modules that will provide state-of-the-art instrumentation and technologies required for vision research. The three core modules are: (1) Ocular Imaging Module; (2) Functional Vision Module; and (3) Molecular Informatics Module. These modules contain equipment that will be maintained and operated by highly skilled technicians that are supervised by established R01 funded investigators. Consolidating these technologies into these modules allow us to bring these techniques and skills to all potential users in our program, which we anticipate will increase productivity in the user laboratories and avoid duplication of equipment and effort. Successful operation of these three modules will bring the best of these technologies to each of the NEI RO1 supported laboratories in this institution. We also envision that these core modules will enhance and sustain the collaborative scientific environment that is a strong feature of the research group supported by these modules. The modules will also enhance productivity and increase collaboration among the participating investigators. These modules will also allow junior investigators to have access to services and research strategies that will help generate preliminary data to support new RO1 application.
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Regulation of Choroidal Neovascularization in Sorsby's Fundus Dystrophy
  • 批准号:
    9900004
  • 项目类别:
  • 资助金额:
    $39.63万
  • 财政年份:
    2017
  • 负责人:
    BELA ANAND-APTE
  • 依托单位:
FGF and hyaluronan-mediated alterations in epithelial-mesenchymal transition and metabolism of RPE cells in Sorsby Fundus Dystrophy.
  • 批准号:
    10408757
  • 项目类别:
  • 资助金额:
    $62.17万
  • 财政年份:
    2017
  • 负责人:
    BELA ANAND-APTE
  • 依托单位:
FGF and hyaluronan-mediated alterations in epithelial-mesenchymal transition and metabolism of RPE cells in Sorsby Fundus Dystrophy.
  • 批准号:
    10636830
  • 项目类别:
  • 资助金额:
    $61.01万
  • 财政年份:
    2017
  • 负责人:
    BELA ANAND-APTE
  • 依托单位:
Role of Retinoic Acid in the Regulation of the Blood-Retinal Barrier.
  • 批准号:
    9769753
  • 项目类别:
  • 资助金额:
    $41.3万
  • 财政年份:
    2016
  • 负责人:
    BELA ANAND-APTE
  • 依托单位:
海外基金