NEI CENTER CORE GRANT FOR VISION RESEARCH

NEI 中心视觉研究核心资助

• 批准号: 9336307
• 负责人: BELA ANAND-APTE
• 金额: $ 63.4万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9336307
• 关键词: Affect; Anterior; Basic Science; Blindness; Center Core Grants; Cilia; Clinic; Collaborations; Conflict (Psychology); Core Grant; Cornea; Data; Development; Disease; Ectopia Lentis; Eligibility Determination; Environment; Epithelial; Equipment; Event; Extracellular Matrix; Eye; Faculty; Fostering; Funding; Generations; Goals; Grant; Health Services Accessibility; Health Services Research; Image; Immunity; Individual; Informatics; Institutes; Institution; Keratin; Keratitis; Laboratories; Liver; Molecular; Patients; Performance; Photoreceptors; Productivity; Research; Research Infrastructure; Research Personnel; Research Support; Resolution; Resources; Retina; Role; Scientist; Series; Services; Structure; Supervision; Support Groups; Techniques; Technology; Translational Research; Vision; Vision research; Visual system structure; base; cost; cost effective; data acquisition; elastography; equipment acquisition; human disease; instrumentation; models and simulation; mouse model; new technology; operation; prevent; programs; ranpirnase; retina blood vessel structure; skills

The overall aim of this NEI Core Grant for Vision Research is to facilitate the application of important technologies in the analysis of the structure, function and disease mechanisms that affect the visual system. The long-term goal of the investigators served by this grant is to preventing blindness and restoring vision. To this end we will develop a series of core modules that will provide state-of-the-art instrumentation and technologies required for vision research. The three core modules are: (1) Ocular Imaging Module; (2) Functional Vision Module; and (3) Molecular Informatics Module. These modules contain equipment that will be maintained and operated by highly skilled technicians that are supervised by established R01 funded investigators. Consolidating these technologies into these modules allow us to bring these techniques and skills to all potential users in our program, which we anticipate will increase productivity in the user laboratories and avoid duplication of equipment and effort. Successful operation of these three modules will bring the best of these technologies to each of the NEI RO1 supported laboratories in this institution. We also envision that these core modules will enhance and sustain the collaborative scientific environment that is a strong feature of the research group supported by these modules. The modules will also enhance productivity and increase collaboration among the participating investigators. These modules will also allow junior investigators to have access to services and research strategies that will help generate preliminary data to support new RO1 application.

这个NEI视觉研究核心补助金的总体目标是促进申请 在结构、功能和疾病分析中的重要技术 影响视觉系统的机制。调查人员的长期目标是 这项拨款的目的是预防失明和恢复视力。为此，我们将开发 一系列核心模块，将提供最先进的仪器， 视觉研究所需的技术。三个核心模块是：（1）眼 成像模块;（2）功能视觉模块;和（3）分子信息学模块。 这些模块包含将由高技能人员维护和操作的设备 由R 01资助的研究人员监督的技术人员。巩固 这些模块中的技术使我们能够将这些技术和技能带给所有人， 潜在用户在我们的计划，我们预计将提高生产力的用户 实验室和避免重复的设备和努力。这些成功的操作 三个模块将把这些技术中最好的技术带到每一个NEI RO 1中 支持实验室在这个机构。我们还设想，这些核心模块将 加强和维持合作的科学环境，这是一个强大的特点， 这些模块支持的研究小组。这些模块还将增强 提高生产力，并加强参与调查人员之间的合作。这些 这些单元还将使初级调查员能够获得服务和研究 这些战略将有助于生成初步数据，以支持新的RO 1应用。