Institute for Integration of Medicine & Science: A Partnership to Improve Health

医学整合研究所

• 批准号: 10704865
• 负责人: ROBERT A CLARK
• 金额: $ 563.56万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-25 至 2030-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10704865
• 关键词: Acceleration; Address; Area; Automation; COVID-19 pandemic; Cities; Clinical Research; Clinical Sciences; Clinical effectiveness; Collaborations; Communities; Community Health Aides; Creativeness; Data; Discipline; Disease; Dissemination and Implementation; Education and Outreach; Effectiveness; Elements; Emergency Situation; Emergency response; Evaluation; Faculty; Fostering; Funding; Future; Goals; Growth; Health; Health Priorities; Health Sciences; Healthcare; Healthcare Systems; Hispanic; Hispanic Populations; Home; Human; Human Resources; Inequity; Informatics; Infrastructure; Institution; Intervention; Knowledge; Latino; Leadership; Learning; Measurable; Medicine; Methods; Mexico; Military Personnel; Minority; Mission; Outcome; Patients; Personal Satisfaction; Population; Process; Program Development; Public Health Informatics; Research; Research Infrastructure; Research Priority; Resources; Rural Population; Science; Services; South Texas; Testing; Texas; Training; Training Support; Translating; Translational Research; Translations; Vision; Work; Workforce Development; austin; care outcomes; clinical practice; clinical translation; data quality; demographics; disparity reduction; dissemination science; diversity and inclusion; evidence base; flexibility; health disparity; health equity; implementation science; improved; innovation; military veteran; novel; opioid epidemic; outcome disparities; population based; process improvement; programs; rapid growth; resilience; response; rural counties; success; synergism; translational barrier

Project Summary-Abstract South-Central Texas is home to San Antonio and Austin, both among the nation’s fastest growing cities. San Antonio, the gateway to South Texas, is the 7th largest city and the largest minority- majority Hispanic/Latino city in the US, whereas Austin is 11th largest. The region also includes many rural counties and several on the US-Mexico border. Given our demographics and rapid growth, our area foreshadows future challenges facing US healthcare, underscoring the national applicability of solutions devised by our hub. In 2006, UT Health Science Center San Antonio established the Institute for Integration of Medicine & Science (IIMS) as the academic home for translational research initiatives, training the translational science workforce, formalizing key strategic partnerships, and creating a community of scholars within a learning healthcare system. Building upon our optimized clinical and translational research infrastructure, IIMS now proposes a 4th cycle of CTSA support in response to PAR-21-293. Our hub seeks to be exceptional in solving clinical and translational science (CTS) roadblocks, translating discoveries into reduced disparities and improved healthcare outcomes across our multi-cultural population. We strive to make our vision a reality through robust strategies for supporting CTS across institutional partners and collaborating organizations, catalyzing successes for transdisciplinary research teams, and implementing programs that produce a creative, collaborative, and culturally diverse translational science workforce. We will achieve our goals through the strategic deployment of resources and expertise developed during 3 cycles of CTSA funding. Our proposal leverages optimized strengths across the spectrum of clinical and translational research to establish the capacity and infrastructure required for high-impact CTS programs. Thus, IIMS will pivot from the study of specific targets/diseases (i.e., clinical translational research) to the discovery of generalizable principles that apply to many targets/diseases (CTS), addressing rate-limiting steps and transforming translation from an empirical process into a predictive science. This guiding tenet is embedded within each Element and Module of this proposal, as well as across our pipeline of training and workforce development programs. We posit that synergies across hub partners will yield CTS innovations and contribute meaningfully to the National CTSA Consortium. Our over-arching Specific Aims are: 1. Catalyze the acceleration of CTS discovery and health disparities impact within a vibrant academic home synergistically integrated with our strategic partners and actively engaged with our diverse communities 2. Capitalize on our extraordinary Hispanic and military/veteran population base to diversify and enhance our interdisciplinary clinical and translational science workforce 3. Implement innovative strategies for evaluation and continuous improvement across all IIMS programs 4. Focus strategically on dissemination and implementation of evidence-based CTS advances with high potential for advancing health equity, both regionally and across the National CTSA Consortium

项目摘要-摘要 得克萨斯州中南部是圣安东尼奥和奥斯汀的所在地，这两个城市都是美国最大的城市之一。 增长最快的城市圣安东尼奥是南德克萨斯州的门户，是第七大城市，也是最大的少数民族城市- 奥斯汀是美国西班牙裔/拉丁裔人口占多数的城市，而奥斯汀是第11大城市。该地区还包括许多农村 县和几个在美国和墨西哥边境。鉴于我们的人口和快速增长，我们的地区预示着 美国医疗保健面临的未来挑战，强调了我们中心设计的解决方案的全国适用性。 2006年，UT健康科学中心圣安东尼奥成立了医学与医学整合研究所。 科学（IIMS）作为转化研究倡议的学术家园，培养转化科学 劳动力，正式确定关键的战略伙伴关系，并在学习中创建学者社区 医疗保健系统。基于我们优化的临床和转化研究基础设施，IIMS现在 根据PAR-21-293，建议第四轮CTSA支持。我们的中心寻求在解决 临床和转化科学（CTS）障碍，将发现转化为减少差异并改善 我们的多元文化人口的医疗保健结果。我们致力于通过强大的 支持跨机构合作伙伴和协作组织的CTS的战略， 为跨学科的研究团队，并实施计划，产生一个创造性的，协作的， 文化多样的翻译科学工作者。我们将通过以下战略部署来实现我们的目标： 在CTSA的3个供资周期中开发的资源和专业知识。我们的方案利用优化的优势 跨临床和转化研究的范围，以建立所需的能力和基础设施， 高影响力的CTS项目因此，IIMS将从特定目标/疾病的研究（即，临床 转化研究）到发现适用于许多靶点/疾病的可推广原则（CTS）， 解决限速步骤，并将翻译从经验过程转变为预测科学。 这一指导原则嵌入在本提案的每个元素和模块中，并贯穿我们的管道 培训和劳动力发展计划。我们认为，跨中心合作伙伴的协同效应将产生CTS 创新并为国家CTSA联盟做出有意义的贡献。我们的具体目标是： 1.在一个充满活力的学术家庭中加速CTS的发现和健康差异的影响 与我们的战略合作伙伴协同整合，并积极参与我们的多元化社区 2.利用我们非凡的西班牙裔和军人/退伍军人人口基础， 我们的跨学科临床和转化科学团队 3.在所有IIMS项目中实施创新的评估和持续改进战略 4.战略重点是传播和实施以证据为基础的CTS进展， 在区域和全国CTSA联盟范围内推进卫生公平的潜力