Institute for Integration of Medicine & Science: A Partnership to Improve Health

圣安东尼奥是南德克萨斯州的门户，是美国第7大城市，也是最大的都会区 西班牙裔人口占多数（63%）。南德克萨斯州的面积和俄亥俄州差不多， 贫穷的西班牙裔人口，糖尿病和肥胖症的发病率不成比例， 由于缺乏医疗保险和难以获得医疗保健而加剧。该地区还包括 许多美国军事设施、现役军人和退伍军人通常有特殊的健康状况， 这些问题包括创伤后应激障碍和创伤的风险增加。不幸的是， 无论是更好地获得保健还是改进保健服务，都无法消除健康差距， 复杂的需求。此外，需要跨整个T1至T4平移谱的研究以消除在T1至T4平移谱中的不确定性。 知识差距，并建立真正的有效性，改善我们人民的保健。 2006年，UTHSCSA成立了医学与科学整合研究所（IIMS），以提高 通过加速科学发现和全面应用， 翻译研究谱例如，IIMS扩大了临床研究单位的数量， 从1到7延伸到德克萨斯州-墨西哥边境，并大大增加了参与者获得临床和 转化科学我们将基于实践的研究网络从2个增加到6个，重点是 不同的流动人口。过去5-10年为满足转化科学劳动力需求所做的努力 多年来，已有100名临床研究硕士毕业，支持了19名成功的KL 2学者， 并建立了新的联合翻译科学博士和证书课程。在本提案中，我们提供 战略，以刺激临床和转化科学的发展，催化研究团队，并实施 培养具有创造性、协作性和文化多样性的科学家的计划。我们的具体目标是： 1.加速临床和转化研究创新和有效的团队科学沿着 整个11到T4的研究范围，提供一个与我们的战略整合的学术家园 伙伴机构。 扩大，多样化，并加强跨学科翻译生物医学的劳动力 科学家 实施有效的方法，不断评估和优化服务， 提高效率，改善流程，降低所有IIMS计划的成本。 相关性（参见说明）： 基于我们通过加速科学发现和改善南德克萨斯州健康状况的愿景， 公共卫生应用，我们将部署战略资源，重点放在我们的普遍挑战， 地区，包括：1）我们服务不足的西班牙裔人口的健康需求，2）特殊的健康问题 面对现役军人和退伍军人群体，以及3）转化科学劳动力的局限性 需要填补关键的知识空白，改善南德克萨斯州和美国的健康状况。

San Antonio, the gateway to South Texas, is the 7^ largest city in the US and the largest metropolitan area with a majority Hispanic population (63%). South Texas is about the size of Ohio, and comprises an impoverished and largely Hispanic population with disproportionate rates of diabetes and obesity, exacerbated by a lack of health insurance and poor access to health care. This region also contains numerous US military installations, and active-duty service members and veterans often have special health issues, including increased risk for post-traumatic stress disorder and traumatic injuries. Unfortunately, neither better access to care nor improved care delivery can eliminate health disparities and meet these complex needs. In addition, research across the full T l to T4 translational spectrum is required to eliminate knowledge gaps and establish real-wortd effectiveness that improves health care for our populations. In 2006, UTHSCSA established the Institute for Integration of Medicine and Science (IIMS) to improve health and reduce disparities by accelerating scientific discoveries and applications across the full translational research spectrum. For example, IIMS expanded the number of clinical research units that extend to the Texas-Mexico border from 1 to 7, and dramatically increasing participant access to clinical and translational science. We increased, from 2 to 6, the Practice-Based Research Networks that focus on diverse ambulatory populations. Efforts to address translational science workforce needs over the past 5-10 years have graduated 100 Masters Clinical Investigation students, supported 19 successful KL2 Scholars, and established new joint Translational Science PhD and Certificate programs. In this proposal, we provide strategies to spur clinical and translational science evolution, catalyze research teams, and implement programs that produce creative, collaborative, and culturally diverse scientists. Our Specific Aims will: 1. Accelerate clinical and translational research innovation and effective team science along the entire 11 to T4 research spectrum by providing an academic home integrated with our strategic partner institutions. Expand, diversify, and enhance the workforce of interdisciplinary translational biomedical scientists. Implement effective methods to continuously evaluate and optimize services, increase efficiencies, improve processes, and reduce costs across all IIMS programs. RELEVANCE (See instructions): Based on our vision of improving the health status of South Texas by accelerating scientific discoveries and public health applications, we will deploy strategic resources that focus on prevalent challenges in our region, including: 1) the health needs of our underserved Hispanic population, 2) the special health issues facing active-duty military and veteran populations, and 3) limitations in the translational science workforce required to fill in critical knowledge gaps and improve health in South Texas and the US.