Training Core

抽象训练核心 今天，与科学和健康相关的研究比以往任何时候都更有前途。一个人几乎跟不上 基因组学、转录组学、蛋白质组学和代谢组学的所有最新发现。新医学 发现和医疗改革的速度远远超出了我们目前的转换能力 在不断发展的临床环境中进行新的测试和治疗。因此，在进行技能培训的同时 板凳到床边的转换所需的仍然是基本的，也迫切需要扩大 一批能够在系统生物学、流行病学/等跨学科领域工作的科学家 将科学发现转化为日常工作所需的卫生服务和实施研究 临床实践。密歇根大学肾脏、泌尿外科和血液学研究的目标 培训网络(UM Kuhr)TL1旨在为早期、学术倾向的科学家和 具有翻译研究领域所需技能和经验的医生 弥合基础科学发现、临床实践和人群健康之间的长期差距。 拟议的培训计划由两个主要部分组成：1)教学课程与 专注于基础科学、生物信息学、临床试验、流行病学、卫生服务研究或 实施科学；2)在构思、实施、 以及传播精心设计的研究项目。为了适应医疗保健的需要 市场，该计划将有广泛的标准来录取博士后和博士后实习生 正在攻读医学博士学位或拥有医学博士学位。在他们项目教员的指导下，实习生将 指导研究背后的哲学、伦理学和理论，以及衍生的方法论技术 来自广泛的基础、临床和公共卫生科学。项目负责人将承担 本计划的管理，虽然进度将由计划学院的P接收器持续监测， 选拔和指导委员会每季度发布一次。学员将被要求将他们的工作报告给 在地方和国家科学会议和UM Kuhr年度会议上的遴选和指导委员会 区域研究休养生息。到培训计划结束时，学员将完成 对高级研究学位和指导研究项目的要求，包括出版他们的 同行评议文献中的发现。根据我们过去的记录，我们机构培训的毕业生 项目处于有利地位，可以建立一个纵向研究议程，并追求一个独立的 学术医学研究生涯。

ABSTRACT – TRAINING CORE Science and health related research is more promising today than ever before. One can scarcely keep up with all the latest discoveries in genomics, transcriptomics, proteomics, and metabolomics. New medical discoveries and health care reforms are emerging at a pace that far exceeds our current capacity to translate new tests and treatments into an ever-evolving clinical environment. As such, while training in the skills required for bench to bedside translation remains fundamental, there is also a compelling need to expand the pool of scientists capable of performing cross-disciplinary areas such as the systems biology, epidemiology/ health services and implementation research necessary to translate scientific discoveries into day-to-day clinical practice. The objectives of the University of Michigan Kidney, Urology and Hematology Research Training Network (UM KUHR) TL1 are to provide early-stage, academically inclined scientists and physicians with the requisite skills and experience across the translational research spectrum to bridge the persistent gaps between basic scientific discovery, clinical practice, and population health. The proposed training program consists of two principal components: 1) Didactic course work with concentrations in basic science, bioinformatics, clinical trials, epidemiology, health services research or implementation science; and 2) Concurrent applied in-depth research experience in the conception, execution, and dissemination of a well-designed research project. In order to adapt to the needs of the healthcare marketplace, the program will have broad criteria to matriculate both predoctoral and postdoctoral trainees who are pursing or have either an MD and/or PhD. Guided by their program faculty preceptor, trainees will be instructed in the philosophy, ethics, and theory behind research, as well as methodological techniques derived from a broad array of basic, clinical, and public health sciences. The Programs Leads will undertake administration of this program while progress will be monitored continuously by Program Faculty Preceptors, and quarterly by the Selection and Mentoring Committee. Trainees will be expected to present their work to the Selection and Mentoring Committee, at local and national scientific conferences and the UM KUHR Annual Regional Research Retreat. By the end of the training program, trainees will have completed both the requirements for an advanced research degree and a mentored research project, including publication of their findings in the peer-reviewed literature. Based on our past records, graduates of our institution’s training programs are well-positioned to establish a longitudinal research agenda and to pursue an independent research career in academic medicine.