Training Core

摘要-培训核心 与科学和健康相关的研究今天比以往任何时候都更有前途。一个人几乎无法跟上 基因组学、转录组学、蛋白质组学和代谢组学的所有最新发现。新的医疗 新发现和医疗改革的速度远远超过了我们目前的翻译能力 新的测试和治疗方法融入不断发展的临床环境。因此，在培训技能的同时， 虽然从工作台到床边的翻译所需的服务仍然是基本的，但也迫切需要扩大 一批能够从事系统生物学、流行病学/医学等跨学科领域工作的科学家 将科学发现转化为日常生活所需的卫生服务和实施研究 临床实践密歇根大学肾脏、泌尿学和血液学研究的目标 培训网络（UM KUHR）TL 1旨在提供早期、有学术倾向的科学家和 具有跨转化研究领域所需技能和经验的医生， 弥合基础科学发现、临床实践和人口健康之间持续存在的差距。 拟议的培训方案包括两个主要组成部分：1）教学课程工作， 在基础科学，生物信息学，临床试验，流行病学，卫生服务研究或 实施科学;和2）同时应用在概念，执行， 和传播一个精心设计的研究项目。为了适应医疗保健的需要， 市场，该计划将有广泛的标准录取博士前和博士后学员谁 正在追求或拥有医学博士和/或博士学位。在他们的项目教师导师的指导下，学员将 指导哲学，伦理学和研究背后的理论，以及方法技术派生 从基础，临床和公共卫生科学的广泛阵列。项目负责人将承担 本计划的管理，而进度将不断监测由计划教师预测， 并由甄选和指导委员会每季度进行一次。受训人员将向以下人员介绍他们的工作： 遴选和指导委员会，在地方和国家科学会议和UM KUHR年度 区域研究撤退。在培训计划结束时，学员将完成 高级研究学位和指导研究项目的要求，包括其出版物 同行评审文献中的发现。根据我们过去的记录，我们机构培训的毕业生 项目处于有利地位，可以建立纵向研究议程并追求独立研究 学术医学的研究生涯。

ABSTRACT – TRAINING CORE Science and health related research is more promising today than ever before. One can scarcely keep up with all the latest discoveries in genomics, transcriptomics, proteomics, and metabolomics. New medical discoveries and health care reforms are emerging at a pace that far exceeds our current capacity to translate new tests and treatments into an ever-evolving clinical environment. As such, while training in the skills required for bench to bedside translation remains fundamental, there is also a compelling need to expand the pool of scientists capable of performing cross-disciplinary areas such as the systems biology, epidemiology/ health services and implementation research necessary to translate scientific discoveries into day-to-day clinical practice. The objectives of the University of Michigan Kidney, Urology and Hematology Research Training Network (UM KUHR) TL1 are to provide early-stage, academically inclined scientists and physicians with the requisite skills and experience across the translational research spectrum to bridge the persistent gaps between basic scientific discovery, clinical practice, and population health. The proposed training program consists of two principal components: 1) Didactic course work with concentrations in basic science, bioinformatics, clinical trials, epidemiology, health services research or implementation science; and 2) Concurrent applied in-depth research experience in the conception, execution, and dissemination of a well-designed research project. In order to adapt to the needs of the healthcare marketplace, the program will have broad criteria to matriculate both predoctoral and postdoctoral trainees who are pursing or have either an MD and/or PhD. Guided by their program faculty preceptor, trainees will be instructed in the philosophy, ethics, and theory behind research, as well as methodological techniques derived from a broad array of basic, clinical, and public health sciences. The Programs Leads will undertake administration of this program while progress will be monitored continuously by Program Faculty Preceptors, and quarterly by the Selection and Mentoring Committee. Trainees will be expected to present their work to the Selection and Mentoring Committee, at local and national scientific conferences and the UM KUHR Annual Regional Research Retreat. By the end of the training program, trainees will have completed both the requirements for an advanced research degree and a mentored research project, including publication of their findings in the peer-reviewed literature. Based on our past records, graduates of our institution’s training programs are well-positioned to establish a longitudinal research agenda and to pursue an independent research career in academic medicine.