Career Enhancement Program

项目摘要 梅奥诊所乳腺癌孢子职业提升计划(CEP)致力于识别 并指导最有潜力开发独立翻译项目的初级教师 乳腺癌研究。这是通过一个严格的审查过程来实现的，旨在确定最 有才华和有前途的候选人，紧随其后的是密集、严格和有效的指导计划。这个 指导计划的基础是多学科指导的建立和最佳运作 由一名高级研究员领导的委员会，具有科学专长并致力于开发下一代 一代转化型乳腺癌研究人员。多学科指导委员会将 由主要导师和补充的临床和/或基础研究人员组成 全面的辅导计划，外加一名统计学家。它被认为是获奖者成功的关键 指导是持续进行的，而且是强有力的。这将通过CEP主任的密切监督来完成 指导过程和获奖者的进展情况。CEP主任将向孢子公司报告- 董事，然后向孢子执行委员会报告。这一密集的监督过程是 成立是因为坚信孢子联席董事的独立发展 研究人员和转化型乳腺癌研究是孢子任务的核心。显性的 预期获奖者将利用向他们提供的资源来发展 独立研究计划和获得乳腺癌研究的独立资金。我们是 要求每年50,000美元(直接成本)来支持该计划。此外，还将追加5万美元。 (直接成本)梅奥诊所癌症中心的支持。每年将颁发100,000美元的奖金，这可以 用于支付工资、技术人员支持和用品。每年将支持一名获奖者，并给予 获奖者可获得最长两年的支持，前提是取得令人满意的进展。到目前为止 CEP是成功的，因为三名CEP获奖者卓有成效，并成功地 在孢子的全部项目中竞争成为项目联合负责人。

Project Summary The Career Enhancement Program (CEP) of the Mayo Clinic Breast Cancer SPORE is committed to identifying and mentoring junior faculty with the greatest potential of developing independent programs in translational breast cancer research. This is accomplished through a rigorous review process aimed at identifying the most talented and promising candidates followed by an intensive, rigorous and effective mentoring program. The mentoring program is based on the establishment and optimal functioning of a Multidisciplinary Mentoring Committee led by a senior investigator with the scientific expertise and commitment to developing the next generation of translational breast cancer researchers. The Multidisciplinary Mentoring Committee will be composed of the primary mentor and the complementary clinical and/or basic investigator necessary for a comprehensive mentoring program plus a statistician. It is viewed as crucial to the success of the awardee that the mentoring be ongoing and robust. This will be accomplished by close oversight by the Director of the CEP of the mentoring process and progress of the awardee. The Director of the CEP will report to the SPORE Co- Directors who, in turn, report to the SPORE Executive Committee. This intensive oversight process was established because of the firm conviction of the SPORE Co-Directors that the development of independent investigators and translational breast cancer research is central to the SPORE mission. The explicit expectation is that the awardees will utilize the resources made available to them for the development of independent research programs and acquisition of independent funding in breast cancer research. We are requesting $50,000 per year (direct costs) to support this program. This will be supplemented by $50,000 (direct costs) of Mayo Clinic Cancer Center support. One award of $100,000 per year will be made, which can be used for salary, technician support, and supplies. One awardee will be supported per year and a given awardee can be supported for up to two years providing satisfactory progress is demonstrated. To date the CEP has been successful in that three CEP awardees have been highly productive and have successfully competed to become Project Co-Leaders in full Projects of the SPORE.