HIV IMPAACT RELATED STUDIES

艾滋病毒影响相关研究

• 批准号: 10021517
• 负责人: BARBARA DRIVER
• 金额: $ 525.86万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-12-01 至 2020-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10021517
• 关键词: AIDS clinical trial group; AIDS/HIV problem; Adolescent; Anti-Retroviral Agents; Charge; Child; Childhood; Clinical; Clinical Trials; Clinical Trials Network; Collaborations; Communicable Diseases; Conduct Clinical Trials; Diagnosis; Disease; Epidemiology; Funding; Grant; HIV; HIV Infections; HIV therapy; Infant; Institution; International; International Aspects; International Maternal Pediatric Adolescent AIDS Clinical Trials Group; Intervention; Leadership; Maternal Health; National Institute of Allergy and Infectious Disease; National Institute of Child Health and Human Development; Opportunistic Infections; Population; Pregnant Women; Prevention; Preventive Intervention; Protocols documentation; Research; Research Personnel; Site; Support Contracts; Symptoms; Therapeutic Agents; U-Series Cooperative Agreements; Vaccines; Vertical Disease Transmission; adolescent health; co-infection; interest; patient population; perinatal HIV; prevent; targeted treatment; transmission process; young woman

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks to support clinical activities for international and domestic pediatric and maternal HIV and other high priority infectious diseases. NICHD provides clinical trial sites to some other clinical trial networks such as the International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) The IMPAACT network and its leadership group are in charge of the creation of all their studies, protocols, and clinical trials. These activities are funded through Grants/Cooperative agreements sponsored by the National Institute of Allergy and Infectious Diseases (NIAID). The IMPAACT Network is a cooperative group of institutions, investigators, and other collaborators mainly focused on evaluating potential therapies for HIV infection and its related symptoms and co-infections in infants, children, adolescents and pregnant women for maternal health. This includes clinical trials of HIV/AIDS interventions for the prevention of mother to child transmission. In 1990 the NICHD began collaborating with the Pediatric AIDS Clinical Trials Group, (PACTG) to expand clinical trial availability at NICHD clinical trial centers/sites. This collaboration made possible to conduct clinical trials by the IMPAACT Network to further evaluate antiretroviral therapeutic agents, other therapies targeted at opportunistic infections, and interventions to prevent perinatal HIV transmission. In recent years, the collaboration is expanding to evaluate potential HIV cure approaches and vaccines. The NICHD will continue providing this Coordinating Center Contract support to the IMPAACT Network providing access to sites and the clinical populations of interest. Scope To perform clinical trials according to the IMPAACT Related protocols maintaining a multi-site network of domestic and international clinical centers to conduct the research on treatment, prevention, diagnosis, epidemiology of HIV infection and disease and its infectious and non-infectious complications in pediatric, adolescent, and maternal patient populations.

尤尼斯·肯尼迪·施赖弗国家儿童健康与人类发展研究所 (NICHD) 寻求支持国际和国内儿科和孕产妇艾滋病毒临床活动 和其他高度优先的传染病。 NICHD 向其他一些临床试验网络提供临床试验站点，例如 国际孕产妇儿科青少年艾滋病临床试验组 (IMPAACT) IMPAACT 网络及其领导小组负责所有研究的创建， 方案和临床试验。这些活动通过赠款/合作协议资助 由国家过敏和传染病研究所 (NIAID) 赞助。这 IMPAACT Network 是一个由机构、研究人员和其他人员组成的合作团体 合作者主要致力于评估艾滋病毒感染的潜在疗法及其 婴儿、儿童、青少年和孕妇的相关症状和合并感染，以促进孕产妇健康。 这包括预防母婴感染艾滋病毒/艾滋病干预措施的临床试验 传播。 1990 年，NICHD 开始与儿科艾滋病临床试验小组合作， (PACTG) 扩大 NICHD 临床试验中心/场所的临床试验可用性。这 合作使得通过 IMPAACT 网络进行临床试验成为可能，以进一步 评估抗逆转录病毒治疗剂、其他针对机会性感染的疗法， 以及预防围产期艾滋病毒传播的干预措施。近年来，双方的合作 扩大评估潜在的艾滋病毒治疗方法和疫苗。 NICHD 将 继续向 IMPAACT 网络提供协调中心合同支持 提供对感兴趣的地点和临床人群的访问。 范围 根据 IMPAACT 相关协议进行临床试验，维护多站点网络 国内外临床中心开展治疗、预防、诊断、 HIV感染和疾病及其感染性和非感染性并发症的流行病学 儿科、青少年和孕产妇患者群体。