Ambient air pollution exposure during pregnancy and longitudinal fetal growth

怀孕期间和胎儿纵向生长期间的环境空气污染暴露

• 批准号: 10003761
• 负责人: Pauline Mendola
• 金额: $ 12.73万
• 依托单位: EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10003761
• 关键词: 3-Dimensional; Abdomen; Acute; Address; Air; Air Pollutants; Air Pollution; Arteries; Biological; Biometry; Birth; Blood Pressure; Body Composition; Caliber; Chronic; Clinic; Clinical; Code; Cohort Studies; Collection; Data; Environmental Exposure; Exposure to; Fatty acid glycerol esters; Femur; Fetal Growth; Fetal Weight; Goals; Head circumference; Hour; Length; Maryland; Maternal Exposure; Measurement; Measures; Modeling; Monitor; National Institute of Child Health and Human Development; Obesity; Organ; Ozone; Particulate Matter; Pregnancy; Radial; Site; Temperature; Thinness; Twin Multiple Birth; Ultrasonography; Universities; Uterus; Visit; ambient air pollution; base; fetal; humerus; insight; prenatal; prenatal exposure; subcutaneous

This project was approved and collection of maternal residential zip code is ongoing. Clinic addresses have been geocoded and preliminary data on ozone, particulate matter <2.5 microns have been assembled from the US EPA CMAQ downscaler model and calculated based on distance to the nearest air quality monitor (radius 10 km and 5 km). Daily exposures are available from the EPA model and hourly exposures were calculated based on monitor data. We are currently working with colleagues at the University of Maryland to retrieve hourly data from air pollution models for the clinical visits. Initial analyses of uterine artery and umbilical doppler results in relation to air pollutants have begun.

本项目已获批，孕产妇居住地邮编正在收集中。诊所地址已进行地理编码，臭氧、<2.5微米颗粒物的初步数据已从美国环保局CMAQ缩小模型中收集，并根据与最近的空气质量监测仪的距离（半径10公里和5公里）进行计算。EPA模型提供了每日暴露量，每小时暴露量是根据监测数据计算的。目前，我们正在与马里兰大学的同事合作，从空气污染模型中检索每小时的数据，用于临床就诊。子宫动脉和脐多普勒结果与空气污染物的关系的初步分析已经开始。