Ambient air pollution exposure during pregnancy and longitudinal fetal growth

怀孕期间和胎儿纵向生长期间的环境空气污染暴露

• 批准号: 10266563
• 负责人: Pauline Mendola
• 金额: $ 2.78万
• 依托单位: EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10266563
• 关键词: 3-Dimensional; Abdomen; Acute; Address; Air; Air Pollutants; Air Pollution; Arteries; Biological; Biometry; Birth; Blood Pressure; Body Composition; Caliber; Chronic; Clinic; Clinical; Code; Cohort Studies; Collection; Data; Environmental Exposure; Exposure to; Fatty acid glycerol esters; Femur; Fetal Growth; Fetal Weight; Goals; Head circumference; Hour; Length; Maryland; Maternal Exposure; Measurement; Measures; Modeling; Monitor; National Institute of Child Health and Human Development; Obesity; Organ; Ozone; Particulate Matter; Pregnancy; Radial; Site; Temperature; Thinness; Twin Multiple Birth; Ultrasonography; Universities; Uterus; Visit; ambient air pollution; base; fetal; humerus; insight; prenatal; prenatal exposure; subcutaneous

This project was approved and collection of maternal residential zip code is ongoing. Clinic addresses have been geocoded and preliminary data on ozone, particulate matter <2.5 microns have been assembled from the US EPA CMAQ downscaler model and calculated based on distance to the nearest air quality monitor (radius 10 km and 5 km). Daily exposures are available from the EPA model and hourly exposures were calculated based on monitor data. We are currently working with colleagues at the University of Maryland to retrieve hourly data from air pollution models for the clinical visits. Initial analyses of uterine artery and umbilical doppler results in relation to air pollutants have begun.

该项目已获批准，正在收集产妇居住地的邮政编码。 对诊所地址进行了地理编码，并从美国环保局CMAQ降尺度模型中收集了关于臭氧和<2.5微米颗粒物的初步数据，并根据与最近空气质量监测器的距离（半径10公里和5公里）进行了计算。 每日暴露量可从EPA模型中获得，每小时暴露量根据监测数据计算。 我们目前正在与马里兰州大学的同事合作，从空气污染模型中检索每小时的数据，用于临床访问。 对子宫动脉和脐部多普勒结果与空气污染物关系的初步分析已经开始。