Bioinformatics Studies of Human Viruses
Bioinformatics Studies of Human Viruses
批准号:
10007524
负责人:
John Spouge
金额:
$59.42万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
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英文摘要
Having studied the statistics of the specific signature residues in the Env protein for SIV infection, and having determined by computation that the founder viruses of the SIV infection differ significantly from the typical virions in the stock inoculum, we examined the changes in the Nef gene and its RNA during the North American HIV epidemic. Using clinical sequence data, Dr Manzourolajdad discovered that the Nef gene had systematically evolved and increased the possibility of alternative folds in Nef RNA. Consequently, we developed general computational tools for identifying alternative folds in riboswitches, to aid in the identification of switches and the corresponding RNA substructures.
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Bioinformatics Studies of Human Viruses
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批准号:10471119
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项目类别:
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资助金额:$16.98万
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财政年份:--
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负责人:John Spouge
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依托单位:
Taxonomics Methods Using DNA
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批准号:10471121
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项目类别:
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资助金额:$7.49万
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财政年份:--
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负责人:John Spouge
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依托单位:
Quantitation Of Viral Reproduction
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批准号:7969216
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项目类别:
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资助金额:$2.76万
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财政年份:--
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负责人:John Spouge
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依托单位:
Global Alignment of Protein Sequences with Position-Specific Scoring Matrices.
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批准号:8558118
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项目类别:
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资助金额:$6.51万
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财政年份:--
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负责人:John Spouge
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依托单位:
Statistics and Algorithms in Evolution
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批准号:9160939
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项目类别:
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资助金额:$2.05万
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财政年份:--
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负责人:John Spouge
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依托单位:
The Statistics of Repeats
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批准号:7735090
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项目类别:
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资助金额:$1.72万
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财政年份:--
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负责人:John Spouge
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依托单位:
The Statistics of Repeats
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批准号:7969248
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项目类别:
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资助金额:$3.87万
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财政年份:--
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负责人:John Spouge
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依托单位:
Analysis of the Performance of Putative Plant Barcodes
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批准号:7969250
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项目类别:
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资助金额:$7.37万
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财政年份:--
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负责人:John Spouge
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依托单位:
Mathematically Rigorous Results In Sequence Matching.
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批准号:10007523
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项目类别:
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资助金额:$2.38万
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财政年份:--
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负责人:John Spouge
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依托单位:
Bioinformatics Studies of Human Viruses
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批准号:8558093
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项目类别:
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资助金额:$23.86万
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财政年份:--
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负责人:John Spouge
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依托单位:
The Statistical Evaluation Of Retrieval Efficiency From A Database.
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批准号:8558108
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项目类别:
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资助金额:$2.17万
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财政年份:--
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负责人:John Spouge
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依托单位:
Statistics and Algorithms in Evolution
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批准号:8149616
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项目类别:
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资助金额:$7.83万
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财政年份:--
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负责人:John Spouge
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依托单位:
Global Alignment of Protein Sequences with Position-Specific Scoring Matrices.
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批准号:8344961
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项目类别:
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资助金额:$9.99万
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财政年份:--
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负责人:John Spouge
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依托单位:
The Statistics of Repeats
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批准号:8943245
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项目类别:
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资助金额:$32.24万
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财政年份:--
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负责人:John Spouge
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依托单位:
Statistics and Algorithms in Evolution
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批准号:8943248
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项目类别:
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资助金额:$23.92万
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财政年份:--
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负责人:John Spouge
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依托单位:
Analysis of the Performance of Putative Barcodes
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批准号:9796766
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项目类别:
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资助金额:$1.13万
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财政年份:--
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负责人:John Spouge
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依托单位:
The Analysis of Signal Elements in Promoter Sequences.
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批准号:8558116
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项目类别:
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资助金额:$30.37万
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财政年份:--
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负责人:John Spouge
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依托单位:
Bioinformatics Studies of Human Viruses
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批准号:10927045
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项目类别:
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资助金额:$41.5万
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财政年份:--
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负责人:John Spouge
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依托单位:
Statistics and Algorithms in Evolution
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批准号:10007527
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项目类别:
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资助金额:$3.57万
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财政年份:--
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负责人:John Spouge
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依托单位:
Mathematically Rigorous Results In Sequence Matching.
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批准号:10261218
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项目类别:
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资助金额:$0.24万
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财政年份:--
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负责人:John Spouge
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依托单位:
海外基金