课题基金 / 基金详情

Bioinformatics Studies of Human Viruses

Bioinformatics Studies of Human Viruses
人类病毒的生物信息学研究
批准号:
10007524
负责人:
John Spouge
金额:
$59.42万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:

项目摘要

项目成果

John Spouge的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Having studied the statistics of the specific signature residues in the Env protein for SIV infection, and having determined by computation that the founder viruses of the SIV infection differ significantly from the typical virions in the stock inoculum, we examined the changes in the Nef gene and its RNA during the North American HIV epidemic. Using clinical sequence data, Dr Manzourolajdad discovered that the Nef gene had systematically evolved and increased the possibility of alternative folds in Nef RNA. Consequently, we developed general computational tools for identifying alternative folds in riboswitches, to aid in the identification of switches and the corresponding RNA substructures.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Bioinformatics Studies of Human Viruses
  • 批准号:
    10471119
  • 项目类别:
  • 资助金额:
    $16.98万
  • 财政年份:
    --
  • 负责人:
    John Spouge
  • 依托单位:
Taxonomics Methods Using DNA
  • 批准号:
    10471121
  • 项目类别:
  • 资助金额:
    $7.49万
  • 财政年份:
    --
  • 负责人:
    John Spouge
  • 依托单位:
Quantitation Of Viral Reproduction
  • 批准号:
    7969216
  • 项目类别:
  • 资助金额:
    $2.76万
  • 财政年份:
    --
  • 负责人:
    John Spouge
  • 依托单位:
Global Alignment of Protein Sequences with Position-Specific Scoring Matrices.
  • 批准号:
    8558118
  • 项目类别:
  • 资助金额:
    $6.51万
  • 财政年份:
    --
  • 负责人:
    John Spouge
  • 依托单位:
海外基金