Reducing the Size and Cost of MRI by Using a Zero-He Moderate-Field MRI Magnet Integrated with a Cryocooled RF Coil

通过使用与低温冷却射频线圈集成的零氦中场 MRI 磁体来减小 MRI 的尺寸和成本

• 批准号: 10081755
• 负责人: Shahin Pourrahimi
• 金额: $ 25.21万
• 依托单位: SUPERCONDUCTING SYSTEMS, INC
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10081755
• 关键词: Adopted; Advanced Development; Ambulances; Applications Grants; Architecture; Beds; Devices; Economics; Funding; Goals; Head; Heart; International; Intervention; Limb structure; Magnetic Resonance Imaging; Manufacturer Name; Measurement; Measures; Medical Device; Noise; Operating Rooms; Performance; Phase; RF coil; Research; Resistance; Scanning; Ships; Signal Transduction; Small Business Innovation Research Grant; Sports; System; Technology; Temperature; Testing; Time; Work; cost; cryostat; design; innovation; point of care; programs; trend

Abstract: This application proposes to demonstrate that the more economic cryogen-free magnets operating at moderate fields of 0.5T-1T, and integrated with cryocooled RF coils, can produce signal to noise ratios (SNR) that are potentially comparable to those of 1.5 T MRI scanners with conventional RF coils. This project paves the way towards high-performance, smaller size, and lower cost MRI scanners suited to the emerging interventional and point-of-care applications. It is well established that reducing the RF coil resistance by cooling is advantageous for either small coils or low fields. Because the required scan time decreases in proportion to the square of SNR, even modest improvements in SNR are highly advantageous, especially in interventional and point-of-care situations. The first Aim of the Phase I effort is to demonstrate the feasibility of obtaining significantly higher SNR by conduction-cooling of RF receive coils, and establish the tradeoffs between field strength, magnet size (cost), and SNR gained by cryocooling of the RF receive coil. The second Aim of Phase I is to use results of this tradeoff study to design a practical cryogen-free magnet for head-MRI that includes an integrated cryocooled RF receive coil that will be built in Phase II of this work. The addition of cryocooled RF receive coils (higher SNR) to the magnet is provided at a small incremental cost to the magnet system. SSI, the applicant, has a proven record in the development of advanced cryogen-free MRI magnets under SBIR funding, and several international medical device companies have adopted (licensed) SSI’s MRI cryogen-free magnet technology.

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