High Resolution Neuro-MRI

描述(由申请人提供)：该项目将开发和制造一个现实的护理点神经磁共振扫描仪，具有新的架构，专门为成像人类的大脑和C-脊柱基于现代低成本磁铁，具有操作容易和低运营成本的特点。一旦扫描仪的功能得到演示，除了大脑之外，扫描仪还可以用来对头部的其他部分进行成像。此外，我们建议的扫描仪具有通孔，允许对大部分公众进行全身扫描，并向农村地区和服务不足地区的公众提供核磁共振扫描。我们打算开发的扫描仪将在任何有电的地方工作。 公共卫生相关性：根据NIH/NIBIB网站的说法，“迫切需要为经历中风和头部损伤等神经紧急情况的患者开发改进的快速诊断信息。”NIBIB将低成本成像列为需要开发护理点技术的四个领域之一。该项目将开发和制造一种逼真的护理点神经MRI扫描仪，该扫描仪具有基于现代低成本磁铁的专门为人脑和C-脊柱成像而设计的新颖架构，具有操作简单和运营成本低的特点。我们称这种B0磁体为现实的原因是：i)在第一阶段的工作中，我们展示了这种磁体的所有关键元素；ii)整个B0磁体及其制冷机和压缩机的重量不到500公斤；iii)拟议的无冷媒磁共振磁体的开发是基于经过验证和可靠的低温超导体，而不是一直在开发的超导体。我们的技术现在就在这里。

DESCRIPTION (provided by applicant): This program will develop and manufacture a realistic Point-of-Care Neurological MRIScanner with a novel architecture specifically designed for imaging a human brain and C-spine based on a modern low cost magnet, which features ease of operation and low operating cost. Once the functionality of the scanner is demonstrated, the scanner can be used to image other parts of the head in addition to the brain. Also, the scanner that we propose has a through bore and allows whole-body scanning on a large fraction of the human public and offers MRI scans to the public in the rural locations as well as under-served areas. The scanner we intend to develop will work wherever there can be electricity. PUBLIC HEALTH RELEVANCE: According to NIH/NIBIB website, "There is a critical need for developing improved and rapid diagnostic information for patients experiencing neurological emergencies such as stroke and head injury." NIBIB lists low-cost imaging as one of the four areas that are in need of Point-of-Care technology development. This program will develop and manufacture a realistic Point-of-Care Neurological MRI Scanner with a novel architecture specifically designed for imaging a human brain and C-spine based on a modern low cost magnet, which features ease of operation and low operating cost. The reasons we refer to this B0 magnet as realistic are: i) In the Phase I work we demonstrated all the key elements of such a magnet, ii) the entire B0 magnet with its cryocooler and compressor weighs less than 500 kg, and iii) development of the proposed cryogen-free MRI magnet is based on proven and reliable low temperature superconductors, and not on superconductors that have been under development. Our technology is here now.