High Resolution Neuro-MRI

描述（由申请人提供）：该项目将开发和制造一种现实的即时神经mri扫描仪，该扫描仪具有新颖的结构，专门设计用于基于现代低成本磁铁的人脑和颈椎成像，其特点是易于操作和低操作成本。一旦扫描仪的功能被证明，除了大脑，扫描仪还可以用来对头部的其他部位进行成像。此外，我们建议的扫描仪有一个通孔，可以对大部分公众进行全身扫描，并为农村地区和服务不足地区的公众提供核磁共振扫描。我们打算开发的扫描仪将在任何有电的地方工作。

DESCRIPTION (provided by applicant): This program will develop and manufacture a realistic Point-of-Care Neurological MRIScanner with a novel architecture specifically designed for imaging a human brain and C-spine based on a modern low cost magnet, which features ease of operation and low operating cost. Once the functionality of the scanner is demonstrated, the scanner can be used to image other parts of the head in addition to the brain. Also, the scanner that we propose has a through bore and allows whole-body scanning on a large fraction of the human public and offers MRI scans to the public in the rural locations as well as under-served areas. The scanner we intend to develop will work wherever there can be electricity. PUBLIC HEALTH RELEVANCE: According to NIH/NIBIB website, "There is a critical need for developing improved and rapid diagnostic information for patients experiencing neurological emergencies such as stroke and head injury." NIBIB lists low-cost imaging as one of the four areas that are in need of Point-of-Care technology development. This program will develop and manufacture a realistic Point-of-Care Neurological MRI Scanner with a novel architecture specifically designed for imaging a human brain and C-spine based on a modern low cost magnet, which features ease of operation and low operating cost. The reasons we refer to this B0 magnet as realistic are: i) In the Phase I work we demonstrated all the key elements of such a magnet, ii) the entire B0 magnet with its cryocooler and compressor weighs less than 500 kg, and iii) development of the proposed cryogen-free MRI magnet is based on proven and reliable low temperature superconductors, and not on superconductors that have been under development. Our technology is here now.