Core C: Translational Neurosciences Core
核心 C:转化神经科学核心
基本信息
- 批准号:10085554
- 负责人:
- 金额:$ 22.73万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-08-06 至 2025-05-31
- 项目状态:未结题
- 来源:
- 关键词:Academic Medical CentersAddressAffectAlgorithmsAreaBehavioralBig DataBiological MarkersCaregiversCategoriesChildClinicalCommunitiesDataData AnalysesData CollectionData SetDatabasesDevelopmentDisciplineDiseaseDown SyndromeEducationElectroencephalogramEnsureEvent-Related PotentialsExperimental DesignsFacultyFundingGoalsHigh Performance ComputingHumanImageIndividualInfantInstitutesIntellectual InterestIntellectual and Developmental Disabilities Research CentersIntellectual functioning disabilityLeadMachine LearningMagnetic ResonanceMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMeasuresMethodsMissionModalityMorphologic artifactsMotionMovementPopulationPreventionProtocols documentationPsychophysiologyResearchResearch DesignResearch PersonnelResourcesScanningScienceScientistServicesSiteSourceTechnical ExpertiseTechniquesTestingTimeTranslationsUniversitiesWorkanalysis pipelineautism spectrum disorderbasebig-data sciencecluster computingcost effectivecost efficientdata acquisitiondata de-identificationdata managementdata pipelinedata warehousedesigndisabilityimage processingimaging capabilitiesimprovedindividualized medicineinnovationinterdisciplinary collaborationmembermouse modelnamed groupneuroimagingneurophysiologynovelprogramspublic health relevancerelating to nervous systemrepositorytargeted treatmenttooltranslational neurosciencevisual tracking
项目摘要
The Translational Neuroscience Core will: 1) provide IDDRC investigators with facilities and services to support
their individual human neuroimaging and psychophysiological research programs in the area of intellectual and
developmental disabilities (IDD); 2) continue to develop trans-species methods for acquiring neuroimaging and
psychophysiological measures in humans with IDD and IDD mouse models; 3) utilize repositories of ‘big data’
at Vanderbilt to develop new tools and discoveries for IDD; 4) facilitate interdisciplinary collaborations among
IDDRC investigators who may or may not have neuroimaging expertise; and 5) ensure that the services
provided are timely, highest quality, and cost-effective. The Translational Neuroscience Core C will support
P50 users in the above areas for magnetic resonance (MR) neuroimaging as well as psychophysiological
measures. The Core’s services can be broadly construed into two different categories: (1) those that are
responsive to investigators’ needs and (2) those that are generative, and provide new directions in IDD
for investigators to leverage. Investigator need-based services provided include assistance in (a) experimental
design, including selecting appropriate tasks for magnetic resonance imaging (MRI) or electroencephalogram
(EEG)/event-related potentials (ERP), (b) identification of the optimal modalities of MR imaging or
EEG/ERP/eye tracking acquisition parameters (c) implementation of MRI and EEG/ERP data collection with
special populations (individuals with various IDDs, especially infants and children), and (d) management and
analysis of MRI and EEG/ERP/eye tracking data. The generative and innovative component of the
Translational Neuroscience Core C focuses on key areas that are of particular interest for IDD researchers:
design of novel experimental paradigms optimized for IDDs, expanding trans-species imaging capabilities,
implementing and augmenting novel data acquisition and analysis methods for measuring neural biomarkers of
IDD, developing robust image processing techniques to handle challenging data (e.g., movement artifacts),
and providing tools to enable optimal establishment, usage, and analysis of ‘big data’ repositories such as
ImageVU. While expertise and resources in neuroimaging, advanced computing, and data management tools
are available at Vanderbilt University, none are tailored for the special needs of those who study IDDs.
The Aims and services in Core C all have the central goal: facilitate cost-efficient discovery that leads to the
prevention and/or amelioration of IDD. Each member of the Core has strong ties to the larger Vanderbilt
community, thus enabling seamless linkages between entities at Vanderbilt that are critical for the Core. The
Core will serve 22 funded IDD research-related projects.
转化神经科学核心将:1)为IDDRC研究人员提供设施和服务支持
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Laurie E Cutting其他文献
Laurie E Cutting的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Laurie E Cutting', 18)}}的其他基金
Neural Correlates of Discourse Processing in Adolescents
青少年话语处理的神经相关性
- 批准号:
10687822 - 财政年份:2022
- 资助金额:
$ 22.73万 - 项目类别:
Neurobiology and Treatment of Reading Disability in NF1
神经生物学和 NF1 阅读障碍的治疗
- 批准号:
10628742 - 财政年份:2022
- 资助金额:
$ 22.73万 - 项目类别:
6/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium Vanderbilt
6/6 六溴环十二烷产前经历和纵向发展 (PRELUDE) 联盟范德比尔特
- 批准号:
10494153 - 财政年份:2021
- 资助金额:
$ 22.73万 - 项目类别:
6/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium Vanderbilt
6/6 六溴环十二烷产前经历和纵向发展 (PRELUDE) 联盟范德比尔特
- 批准号:
10661775 - 财政年份:2021
- 资助金额:
$ 22.73万 - 项目类别:
Early Academic Achievement and Intervention Response: Role of Executive Function
早期学业成就和干预反应:执行功能的作用
- 批准号:
10329261 - 财政年份:2021
- 资助金额:
$ 22.73万 - 项目类别:
6/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium Vanderbilt
6/6 六溴环十二烷产前经历和纵向发展 (PRELUDE) 联盟范德比尔特
- 批准号:
10380490 - 财政年份:2021
- 资助金额:
$ 22.73万 - 项目类别:
6/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium Vanderbilt
6/6 六溴环十二烷产前经历和纵向发展 (PRELUDE) 联盟范德比尔特
- 批准号:
10748148 - 财政年份:2021
- 资助金额:
$ 22.73万 - 项目类别:
相似海外基金
Rational design of rapidly translatable, highly antigenic and novel recombinant immunogens to address deficiencies of current snakebite treatments
合理设计可快速翻译、高抗原性和新型重组免疫原,以解决当前蛇咬伤治疗的缺陷
- 批准号:
MR/S03398X/2 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Fellowship
Re-thinking drug nanocrystals as highly loaded vectors to address key unmet therapeutic challenges
重新思考药物纳米晶体作为高负载载体以解决关键的未满足的治疗挑战
- 批准号:
EP/Y001486/1 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Research Grant
CAREER: FEAST (Food Ecosystems And circularity for Sustainable Transformation) framework to address Hidden Hunger
职业:FEAST(食品生态系统和可持续转型循环)框架解决隐性饥饿
- 批准号:
2338423 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Continuing Grant
Metrology to address ion suppression in multimodal mass spectrometry imaging with application in oncology
计量学解决多模态质谱成像中的离子抑制问题及其在肿瘤学中的应用
- 批准号:
MR/X03657X/1 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Fellowship
CRII: SHF: A Novel Address Translation Architecture for Virtualized Clouds
CRII:SHF:一种用于虚拟化云的新型地址转换架构
- 批准号:
2348066 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Standard Grant
BIORETS: Convergence Research Experiences for Teachers in Synthetic and Systems Biology to Address Challenges in Food, Health, Energy, and Environment
BIORETS:合成和系统生物学教师的融合研究经验,以应对食品、健康、能源和环境方面的挑战
- 批准号:
2341402 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Standard Grant
The Abundance Project: Enhancing Cultural & Green Inclusion in Social Prescribing in Southwest London to Address Ethnic Inequalities in Mental Health
丰富项目:增强文化
- 批准号:
AH/Z505481/1 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Research Grant
ERAMET - Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
ERAMET - 快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10107647 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
EU-Funded
Ecosystem for rapid adoption of modelling and simulation METhods to address regulatory needs in the development of orphan and paediatric medicines
快速采用建模和模拟方法的生态系统,以满足孤儿药和儿科药物开发中的监管需求
- 批准号:
10106221 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
EU-Funded
Recite: Building Research by Communities to Address Inequities through Expression
背诵:社区开展研究,通过表达解决不平等问题
- 批准号:
AH/Z505341/1 - 财政年份:2024
- 资助金额:
$ 22.73万 - 项目类别:
Research Grant