ADHD heterogeneity, mechanisms, and risk profile
ADHD 异质性、机制和风险状况
基本信息
- 批准号:10083596
- 负责人:
- 金额:$ 11.14万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-03-17 至 2021-12-31
- 项目状态:已结题
- 来源:
- 关键词:19 year oldAffectAlgorithmsAttention deficit hyperactivity disorderCaringCharacteristicsChildClinicalDataDevelopmentDevelopmental CourseEmotionalFamilyHeterogeneityImpairmentInformal Social ControlInstructionInterventionKnowledgeLongitudinal StudiesLongterm Follow-upMeasuresOutcomePopulationPublic HealthQuality of lifeRiskSchoolsSyndromeTranslatingadvanced analyticsclinical careclinical decision-makingclinical practiceclinical predictorsclinical translationcognitive controlcomputerized toolsemotion regulationfollow-upimprovednext generation
项目摘要
ADHD remains a serious public health concern particularly in relation to long-term outcome, with recent
follow up data from other projects, such as the MTA study, suggesting that current assessment and
sustained treatment practices do not much alter clinical course. In addition, societal and clinical concerns
remain about mis-identification of children with ADHD who need care, because some children seem to
improve developmentally, while others have poor outcomes. While a great deal is known about the
correlates of developmental course, little of this knowledge has translated to clinical practice, and in
particular to clinical prediction—essentially, deciding whether a child, presenting with ADHD, requires
intervention or for whom a clinician can afford to wait and observed. We have previously made progress
here by re-conceptualizing ADHD as a problem in self-regulation involving cognitive control as well as
emotion regulation and emotionality. This has helped us find new and valid sub-profiles that are clinically
predictive. We follow that up here and add new effort to use advanced computational tools to predict
clinical course over a developmental period from 7-19 years of age, using a range of measures at different
levels of analysis, and thus to develop algorithms that could point the way toward next-generation clinical
translation from longitudinal studies.
RELEVANCE (See instructions):
ADHD continues to be a serious and impairing syndrome for millions of children, affecting families, schools,
and life quality. While a great deal is known about the correlates of ADHD, this information has not
translated sufficiently into more efficient clinical decision-making that recognizes the variety of children
within this population. This project seeks to use advanced analytics and long-term follow up data to identify
better ways to identify groups of children with ADHD with characteristic profiles to improve clinical care.
多动症仍然是一个严重的公共卫生问题,特别是与长期结果有关
项目成果
期刊论文数量(0)
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{{ truncateString('JOEL T NIGG', 18)}}的其他基金
Developmental origins and early detection of ADHD and dysregulatory psychopathology
ADHD 和失调性精神病理学的发育起源和早期发现
- 批准号:
10537406 - 财政年份:2022
- 资助金额:
$ 11.14万 - 项目类别:
Developmental origins and early detection of ADHD and dysregulatory psychopathology
ADHD 和失调性精神病理学的发育起源和早期发现
- 批准号:
10320345 - 财政年份:2021
- 资助金额:
$ 11.14万 - 项目类别:
Developmental origins and early detection of ADHD and dysregulatory psychopathology
ADHD 和失调性精神病理学的发育起源和早期发现
- 批准号:
10733853 - 财政年份:2021
- 资助金额:
$ 11.14万 - 项目类别:
Developmental origins and early detection of ADHD and dysregulatory psychopathology
ADHD 和失调性精神病理学的发育起源和早期发现
- 批准号:
10095671 - 财政年份:2021
- 资助金额:
$ 11.14万 - 项目类别:
Developmental origins and early detection of ADHD and dysregulatory psychopathology
ADHD 和失调性精神病理学的发育起源和早期发现
- 批准号:
10517283 - 财政年份:2021
- 资助金额:
$ 11.14万 - 项目类别:
The Impact of Maternal Obesity and Poor Antenatal Nutrition on Offspring RDoC Dimensions and Risk for Neurodevelopmental Disorders
母亲肥胖和产前营养不良对后代 RDoC 维度和神经发育障碍风险的影响
- 批准号:
10176597 - 财政年份:2018
- 资助金额:
$ 11.14万 - 项目类别:
The Impact of Maternal Obesity and Poor Antenatal Nutrition on Offspring RDoC Dimensions and Risk for Neurodevelopmental Disorders
母亲肥胖和产前营养不良对后代 RDoC 维度和神经发育障碍风险的影响
- 批准号:
9762210 - 财政年份:2018
- 资助金额:
$ 11.14万 - 项目类别:
The Impact of Maternal Obesity and Poor Antenatal Nutrition on Offspring RDoC Dimensions and Risk for Neurodevelopmental Disorders
母亲肥胖和产前营养不良对后代 RDoC 维度和神经发育障碍风险的影响
- 批准号:
10407484 - 财政年份:2018
- 资助金额:
$ 11.14万 - 项目类别:
The Impact of Maternal Obesity and Poor Antenatal Nutrition on Offspring RDoC Dimensions and Risk for Neurodevelopmental Disorders
母亲肥胖和产前营养不良对后代 RDoC 维度和神经发育障碍风险的影响
- 批准号:
10700421 - 财政年份:2018
- 资助金额:
$ 11.14万 - 项目类别:
ADHD biotypes using genetic and imaging approaches
使用遗传和成像方法进行多动症生物型
- 批准号:
8706969 - 财政年份:2013
- 资助金额:
$ 11.14万 - 项目类别:
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